Science Quiz / Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Score 0/43 Timer 20:00
Microbe that moves from cell to cell without going extracellular
Microbe that inhibits phagolysosome fusion
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Inhibits cyclosporine by binding FKBP
Expresses sialic acid which inhibits C3 and C5 convertases
Chimeric mAb
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Anti-TNF with chimeric receptor
Inhibits purine synthesis
Humanized mAb
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
Inhibits DHFR, lowers purine levels
Capsular polysaccharide inhibits phagocytosis
Anti-CD20 chimeric monoclonal antibody
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Microbe that crosses the placenta and can cause meningitis in newborns
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Virus that inhibits antigen presentation by interfering with TAP transporter
Inhibits mTOR and prevents T cells from making proteins for proliferation
Monoclonal antibody indicated for B lymphomas
Inhibits IL-10 synthesis, good for tx EBV
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Human antibody
Tx of methotrexate toxicity
Mouse mAb
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Tx of acrolein toxicity
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
SAP protein in XLP cannot bind this molecule
Chimeric anti-TNF monoclonal antibody
Inhibits IMP dehydrogenase, lowers dGTP levels
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Immunosuppressant that inhibits T-independent B cell activation
Lowers pyrimidine nucleotide levels
M protein blocks C3 binding to organism and C3b binding to complement receptors
Fully human monoclonal antibody against TNF
Produces catalase, resisting ROS in phagocytes
Synthesizes modified LPS that resists peptide antibiotics
Expresses NK inhibitor factor and blocks killing by NK cells
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin

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