Science Quiz / Transplantation & Tumor Immunology

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HintAnswerExtra
Antibodies present in blood group B
Women suffering from this immunodeficiency cannot give birth
Endothelium expresses class II MHC and sometimes B7 and starts to behave like a lymph node in what type of graft rejection?
Immunosuppressive cytokine that can be secreted by tumors to promote angiogenic environment
Mechanism in acute humoral rejection in which the system stops reacting and tissue survives
What type of cell is critical in pregnancy to suppress alloreactivity to the fetus?
Class II MHC molecule that helps NK cells convert to NK2 phenotype (pro-angiogenic, non-cytolytic)
Half-life of a kidney even with immunosuppressants
Antibodies in the recipient that are reactive with the foreign tissue or against MHC molecules of the graft is likely to cause what type of graft rejection?
Alloantibodies (and production of new antibodies against the graft) and host CTLs against major and minor alloantigens cause what type of graft rejection?
HintAnswerExtra
Tx in acute humoral rejection to remove anti-donor antibodies
Human antibody
Antibodies present in blood group AB
Antibodies present in blood group O
Chimeric mAb
Prophylactic tx of hemolytic disease of newborn
Antibodies present in blood group A
Humanized mAb
Inhibitor of acute humoral rejection
Mouse mAb

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