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Neurotransmitter DECREASED in Alzheimer's, Huntington's, and REM sleep
MCC of multiple intracranial mass in AIDS
Parieto-occipital demyelination
Connects mammillary bodies with anterior thalamus
Bilateral loss of pain and thermal sense at that level
Drug-induced Parkinsonism
Cholinesterase inhibitor to treat Alzheimer's
Pituitary tumor causes this visual defect
Neural tube defects are detectable by
Duchenne and Becker's muscular dystrophies have x-linked recessive defect in
Dementia, myoclonus, periodic EEG, rapid progression
Lesion here causes internuclear ophthalmoplegia
Linked to von Hippel Lindau disease
Huntington's disease chromosome
Global loss of cortex
Lidocaine, mepivacaine, bupivacaine are what type of esters?
Distal subararachnoid hemorrhage
Seizure of stiffening
MCC of fungal meningitis
Lesion here causes nonfluent aphasia with intact comprehesion
Treatment of ALD
Nucleus that synthesizes 5HT
Integrative center that controls homeostasis
CD20 stains B-cells in this tumor
Reversible, acute confusion, nystagmus, ataxia
Lesion of both Broca's and Wernicke's areas causes
Can cause watershed zone stroke between territories, usually from cardiopulmonary arrest or severe shock
In closed/narrow angle glaucoma, what should you NOT give to the pt?
Cause of stroke in young people
Increase in ICP, elevated optic disk w/ blurred margins, bigger blindspot
Huntington's drug, dopamine receptor antagonist
ALD genetics
Lateral geniculate nucleus input
Huntington's chorea result of loss of what neurotransmitter?
Psammoma bodies
Destructive, hemorrhagic lesions in temporal and frontal lobes
Procaine, cocaine, tetracaine are what type of anesthetics?
Nemaline myopathy autosomal dominant form mutation
Acute, painless monocular loss of vision; pale retina and cherry-red macula
MCC of bacterial meningitis in adults
Butterfly endothelial proliferation, pleiomorphism, necrosis, astrocytic hypercellularity
MC fungal infxn found at autopsy
Retinoic acid analog, teratogenic
MLD enzyme
Appearance of increased CSF in atrophy
Many small gyri that only have 2 layers
Neurofibromatosis type I mutation
Lewy body protein
Diffuse petechial hemorrhages in white matter
Lesion here causes ipsilateral limb ataxia, falling to side of lesion
Axons get incorporated into this tumor, usually on peripheral nerves and roots
Fluctuating cognitive ability, visual hallucinations, extrapyramidal signs
Cowdry A inclusions
Lesion here causes truncal ataxia, dysarthria
Nucleus that synthesizes ACh
Lesion here causes fluent aphasia with impaired comprehension
Co-deletion of 1p19q linked to survival of 120 months (vs. 12)
Autosomal recessive defect in frataxin
Hairlike astrocytic processes
Friedrich's ataxia patients have poor handling of what?
Amorphous exudate around microvessels
Focal loss of previously formed cortex
Epilepsy drug that auto-induces its own metabolism
Loss of bilateral pupillary constriction when light is shone in affected eye, due to optic nerve damage or retinal detachment
CSF: Increased lymphocytes, increased pressure, slightly increased protein. What kind of meningitis?
Kayser-Fleischer rings
NMDA blocker to treat Alzheimer's
Nemaline myopathy autosomal recessive form mutation
Lesion of the arcuate fasciculus causes
Parkinson's drug that selectively inhibits MAO-B
First histological feature of ischemic brain disease
Lesion of the subthalamic nucleus results in
Treatment of Wilson's disease
Ipsi loss of fine touch/position, ipsi spastic paresis, contra loss of pain/temp, ipsi flaccid paresis at level of lesion
Carbon monoxide causes bilateral necrosis of the
Commonly found at gray-white junction
Protein inclusions in Parkinson's disease
Paraventricular nucleus makes
Tumor of endothelial precursors
Verocay body
Seizure of quick, repetitive jerks
Defects in gyral formation
Neurotransmitter INCREASED in schizophrenia, DECREASED in Parkinson's and depression
Connects amygdala with hypothalamus, mammillary body
Painless, bilateral opacification of the lens, loss of vision
Lesion here causes eyes to look toward lesion
Cowdry B inclusions
Extracellular beta-amyloid plaques and secondary intracellular tau tangles
Neurotransmitter synthesized by the arcuate nucleus
MLD genetics
Lesion here results in reduced levels of arousal and wakefulness (e.g. coma)
Can compress optic chiasm or cavernous sinus, cause hyperprolactinemia
Proximal muscle weakness, pain
Nucleus of visceral sensory information (e.g. taste, baroreceptors, gut distention)
Lateral geniculate nucleus output
Nucleus that synthesizes NE
Vacuolar myelopathy, looks like B12 deficiency
Causes thiamine deficiency, hepatic failure, hyponatremia, central pontine myelonecrosis, cerebellar degeneration, necrosis of corpus callosum
Can cause Wernicke-Korsakoff syndrome
Internal nuclei at biopsy
Multinuclear macrophage (globoid cell)
Guillain-Barre of the CNS
Replicates in skeletal muscle and ascends to CNS via retrograde transport
Pleiomorphism, but no angiogenesis
Knife-edge gyri, disinhibition, dementia
Lesion here causes eyes to look away from side of lesion
From embryonal stem cells, arises from Rathke's pouch
MCC of bacterial meningitis in children
Methanol causes necrosis of the
Mickey Mouse midbrain
Floppy infant, nonprogressive weakness, normal serum muscle enzymes
Permanent memory disturbance and confabulation
MCC sporadic encephalitis
Synuclein inclusions of PSP found where?
Impaired muscle relaxation, distal wasting, frontal bald hatchet face, and endocrine abnormalities
Dorsal columns damage, loss of fine touch and position sense
Photopigment present in ganglion cells in the retina whose axons transmit info to the suprachiasmatic nucleus
Krabbe's disease accumulation
Drug used to treat malignant hyperthermia
Large, often wedge shaped, large caliber atrial and venous channels, gliotic and hemosider-stained tissue between channels
Periventricular plaques and lymphocytes
ALS treatment
Lesion here causes Wernicke-Korsakoff syndrome (confusion, ophthalmoplegia, memory loss, confabulation)
Causes retinal edema and ganglion cell degeneration, blindness
Connects hippocampus with hypothalamus, mammillary body
Supranuclear ophthalmoparesis, rigidity, gait disturbance
Lesion here causes alexia and agraphia
Complex malformation of anterior and posterior neuropores
Neurotransmitter DECREASED in anxiety, depression
Hemorrhagic necrosis on crests of cortical surface
Neurotransmitter DECREASED in anxiety, Huntington's
Treatment of thrombotic focal ischemia
Parkinsonism, ataxia, autonomic dysfunction
Tumor that occurs in the ventricles
Paralysis of vertical gaze, absence of convergence, pupillary disturbance, non-communicating hydrocephalus
Distal muscle weakness, NO pain
Ground glass inclusions, pleimorphic astrocytes
Alzheimer type II astrocytes, Opalski cells
GI complaints, cutaneous features, Mees' lines on the nails, severe axonal neuropathy
Lesion here causes anterograde amnesia
Lobar intracerebral hemorrhage
Wilson's disease genetics
Proximal subarachnoid hemorrhage
Neurotransmitter INCREASED in anxiety, DECREASED in depression
Destruction of a piece of germinal matrix causing part of the cortex to fail to develop
Central pontine myelonecrosis caused by rapid correction of
Connects brainstem nuclei (aminergic) and hypothalamus, PFC
Area between ACA/MCA, PCA/MCA; damaged in severe hypotension causing 'man in a barrel' syndrome
Seizure of alternating stiffening and movement
Area in the brain where Alzheimer's usually begins
Alzheimer's is associated with what chromosome?
Binds endothelial enzymes and disrupts BBB
Supraoptic nucleus makes
Medial geniculate nucleus output
Lesion here causes left hemineglect
Defects in prosencephalic cleavage
Wilson's disease patients have defect of handling what?
CSF: Elevated PMNs, low glucose, elevated protein. What kind of meningitis?
Meningioma may have deletion of what chromosome?
Medial geniculate nucleus input
Degeneration of dorsal and lateral white matter columns with demyelination, macrophage infiltration and axonal loss
Lesion here causes disinhibition and deficits in concentration, orientation, judgment, may have re-emergence of primitive reflexes
Cerebellum receives contralateral cortical input via the
Separation of neurosensory layer of retina from pigment epithelium, degeneration of photoreceptors, vision loss
Treatment of Guillain-Barre
Tumor lined with ciliated cells
Part of the hypothalamus responsible for thermoregulation
Lymphocytic perivascular cuffing. What kind of meningitis?
Output nerve fiber of the cerebellum
Globose tau tangles
Rosenthal fibers
Cerebellum receives ipsilateral proprioceptive information via the
Center of conjugate vertical gaze
'Drop' seizure, commonly mistaken for fainting
Varying caliber vessels without intervening neural parenchyma, oozes blood
Pick's body protein
Lateral medullary syndrome, PICA occluded
MC intracranial PNET
Hypertension causes thickening but paradoxical weakening of perforating areas
Band of grey matter underneath the white
Soap bubble cysts
Obligate intracellular, calcified granulomas
Floppy infant, normal enzymes
Primary CNS lymphoma
Homer Wright rosettes
Nucleus that synthesizes GABA
Caseating granulomata along vessels in meninges and brain parenchyma
Lesion here causes Kl├╝ver-Bucy syndrome (hyperorality, hypersexuality, disinhibited behavior)

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Created Jun 19, 2012ReportNominate
Tags:extra, review, term

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