Science Quiz / Generations of Cephalosporins

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Can you name the Cephalosporin?

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Crosses BBB
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
First generation oral surgical prophylaxis
Fourth generation cephalosporin for pseudomonas
Active against MRSA
Second generation for otitis media and bacterial bronchitis
Only third generation good for penicillin resistant pneumococci
HintType
Third generation cephalosporin for pseudomonas
Binds PBP 2' (2a)
Intra-abdominal surgery prophylaxis
Intramuscular surgical prophylaxis
Widely used at the Texas Medical Center
Establishes good levels in CSF relative to concentrations need to inhibit or kill

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