Science Quiz / BS Drugs

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Side effects hypertensive crisis with tyramine-containing foods, OTC weight loss drugs, decongestants, DA drugs
Side effect possible liver failure
SSRI good for patients on multiple drugs
Drug class of Citalopram
Trade name: Paxil
Side effect priapism
What antidepressant should you avoid giving anxiety pt because it can cause agitation and increase anxiety?
Antihistamine side effects, good for cancer pts
2nd generation Haldol
Atypical antidepressant
Trade name: Lexapro
Trade name: Effexor
Trade name: Clozaril
Trade name: Seroquel
Trade name: Invega
High-potency typical antipsychotic
Start slowly and titrate
Drug class of Atomoxetine
Drug class of Duloxetine
Trade name: Cymbalta
2-3 day+ half life, also weekly formulation
No monitoring required
Trade name: Adderall
Treatment resistant depression
Suicide prevention
Trade name: Remeron
Drug class of Sertraline
Side effect toxic epidermal necrolysis
Trade name: Prozac
BZD receptor --> enhances GABA effect --> hyperpolarize
Serotonin PRESYNAPTIC reuptake inhibitor
Side effects agitation, akathisia, less sedating
Low-potency typical antipsychotic
Block 5HT, NE reuptake; block a1/H1/mACh
5HT1A partial agonist
Trade name: Zoloft
Trade name: Straterra
Anxiolytic in pregnancy category D (do not use)
Trade name: Tofranil
Trade name: Lamictal
Off-label treats mania
Trade name: Tegretol
Trade name: Haldol
Tx anxiety, alcohol withdrawal, insomnia, seizures
Trade name: Depakote
TCA for panic disorder
Trade name: Celexa
Not approved for depression
Drug class of Paroxetine
Mood stabilizer
Drug class of Mirtazapine
Drug class gold standard for tx of anxiety disorders
Historic for depression, current for pain management
a2 antagonist --> disinhibit NE release, increase 5HT
Drug class of Venlafaxine
Antipsychotic approved for peds
Inhibits 5HT reuptake, a1 and 5HT2A/C antagonist
Low dose: atypical antipsychotic; High dose: typical antipsychotic
Drug class of Clonidine and Guanfacine
Side effect SA node interference
Trade name: Pristiq
Trade name: Luvox
Contraindicated in porphyria
Dose-related increased BP
Contraindicated in seizure, electrolyte disorders
Trade name: Zyprexa
Mechanism of antipsychotics w/ long term side effect of tardive dyskinesia
Trade name: Anafranil
Interactions w/ Warfarin, phenytoin, valproic acid
Very sedating (short term), very high weight gain (long term) atypical antipsychotic
Dopamine activity may be useful in brain injury
GABA receptor agonist --> increase chloride ion conductance --> hyperpolarize
High doses can cause EPS, increased prolactin
3rd generation Haldol
Drug class of Fluoxetine
Emergency antipsychotic
Side effects rash (--> SJS), agranulocytosis, hyponatremia
Best SNRI for pts with hypertension
Trade name: Risperdal
Trade name: Focalin
Trade name: Geodon
Trade name: Vyvanse
Trade name: Abilify
Trade name: Wellbutrin
Side effects increased QTc, ↓ weight gain/ cardiometabolic risk
Very lethal in overdose, increased QT interval
Trade name: Dexedrine
Atypical antipsychotic w/ no EPS or prolactin side effects
Trade name: Serzone
D2 partial agonist, 5HT2A antagonist
Trade name: Thorazine
Trade name: Ritalin, Concerta
Tx for panic disorder, OCD
Historical use for anxiety, replaced by benzos
Anticonvulsant that inhibits voltage-gated Na+ channels, glutamate release, ?Ca2+ channels?
Antipsychotic w/ agranulocytosis as short-term side effect
Serotonin agonist and reuptake inhibitor (SARI)
Lorazepam, Oxazepam, Temazepam are the preferred benzos because they do not require what?
Trade name: Buspar

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