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QUIZ: Can you name the drug?

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Trade name: Effexor
Trade name: Depakote
Trade name: Prozac
Treatment resistant depression
Anticonvulsant that inhibits voltage-gated Na+ channels, glutamate release, ?Ca2+ channels?
Very lethal in overdose, increased QT interval
Trade name: Dexedrine
Trade name: Paxil
Trade name: Adderall
Atypical antipsychotic w/ no EPS or prolactin side effects
Antipsychotic w/ agranulocytosis as short-term side effect
Historic for depression, current for pain management
Drug class of Sertraline
Trade name: Abilify
Dose-related increased BP
Antihistamine side effects, good for cancer pts
Mood stabilizer
Anxiolytic in pregnancy category D (do not use)
Drug class of Citalopram
Antipsychotic approved for peds
GABA receptor agonist --> increase chloride ion conductance --> hyperpolarize
3rd generation Haldol
Tx for panic disorder, OCD
Trade name: Remeron
Suicide prevention
Side effect possible liver failure
Side effects rash (--> SJS), agranulocytosis, hyponatremia
5HT1A partial agonist
SSRI good for patients on multiple drugs
Low dose: atypical antipsychotic; High dose: typical antipsychotic
Start slowly and titrate
Drug class of Fluoxetine
What antidepressant should you avoid giving anxiety pt because it can cause agitation and increase anxiety?
Off-label treats mania
Drug class gold standard for tx of anxiety disorders
No monitoring required
Drug class of Atomoxetine
Drug class of Mirtazapine
Trade name: Invega
Trade name: Serzone
Trade name: Cymbalta
Trade name: Celexa
Trade name: Thorazine
Trade name: Haldol
Serotonin PRESYNAPTIC reuptake inhibitor
High-potency typical antipsychotic
2nd generation Haldol
Historical use for anxiety, replaced by benzos
High doses can cause EPS, increased prolactin
Side effect priapism
Interactions w/ Warfarin, phenytoin, valproic acid
Drug class of Duloxetine
TCA for panic disorder
Trade name: Clozaril
Inhibits 5HT reuptake, a1 and 5HT2A/C antagonist
Block 5HT, NE reuptake; block a1/H1/mACh
Trade name: Tofranil
D2 partial agonist, 5HT2A antagonist
Trade name: Lexapro
Atypical antidepressant
Trade name: Luvox
Low-potency typical antipsychotic
Tx anxiety, alcohol withdrawal, insomnia, seizures
Trade name: Zoloft
Side effect SA node interference
Side effects agitation, akathisia, less sedating
2-3 day+ half life, also weekly formulation
Dopamine activity may be useful in brain injury
Trade name: Wellbutrin
Trade name: Geodon
Contraindicated in porphyria
Serotonin agonist and reuptake inhibitor (SARI)
Best SNRI for pts with hypertension
Trade name: Vyvanse
Trade name: Straterra
Not approved for depression
a2 antagonist --> disinhibit NE release, increase 5HT
Drug class of Paroxetine
Trade name: Zyprexa
Very sedating (short term), very high weight gain (long term) atypical antipsychotic
Lorazepam, Oxazepam, Temazepam are the preferred benzos because they do not require what?
Trade name: Focalin
Side effects increased QTc, ↓ weight gain/ cardiometabolic risk
BZD receptor --> enhances GABA effect --> hyperpolarize
Side effect toxic epidermal necrolysis
Trade name: Ritalin, Concerta
Drug class of Clonidine and Guanfacine
Trade name: Buspar
Contraindicated in seizure, electrolyte disorders
Mechanism of antipsychotics w/ long term side effect of tardive dyskinesia
Trade name: Tegretol
Trade name: Seroquel
Drug class of Venlafaxine
Trade name: Risperdal
Emergency antipsychotic
Trade name: Anafranil
Trade name: Pristiq
Trade name: Lamictal
Side effects hypertensive crisis with tyramine-containing foods, OTC weight loss drugs, decongestants, DA drugs

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