Science Quiz / MVST1B BOD Pathology Viruses

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QUIZ: Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
causes bronchitis, recent talk of vaccine
subtype of herpes causing cold sores
associated with cervical cancer
can cause congenital malformation thus vaccinated against
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
causes membrane modification
Used to deliver smallpox vaccine
a toga/flavi virus causing acute and chronic hepatitis
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
Retrovirus
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
causes common cold and susceptibility to secondary infection
dsDNA virus replicating cytosolicly as contains transcription materials in virion
encephalitis causing toga/flavi virus
Generally infectious as M-tropic, mutating to T-tropic later
zoonotic systemic and cns infection, high morbidity
causes acute enteric infection and myelitis in the CNS
Codes ribonucleotide reducing enzymes (produces dNTP)
bullet shaped helical capsid
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
A corona virus
Can induce cell transformation
persistent infection causing common warts or genital warts or genital warts
a rhabdo virus
a paramyxo virus
subtype of herpes causing genital herpes
causes contagious neoplastic disease in chickens
Enter best matching virusVirus
Toga/flavi virus, classical version of recent pandemic
related to measles and resp syncytial virus, entering via resp tract
causes Kaposi's sarcoma
Successfully targetted by interferon therapy
codes Fc receptor molecules to evade antibody response
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
a picorna virus
targetted by tamiflu
causes burkitt's lymphoma and glandular fever
acute in b cells and latent in memory b cells
a reo virus - causes infantile diarrhoea, superficial and acute
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
targetted by a sialic acid analogue
Codes soluble interferon receptors
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
Codes a viral EGF for cell stimulation
faeco-oral transmitted infection targetted by a killed vaccine
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
papova virus causing experimental rodent tumors
systemic infection spread along blood/lymph/nerve tracts
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
A hepadna virus
A calci virus, responsible for winter vomiting disease
Main example of an orthomyxovirus
targetted by aciclovir/acyclovir
causes a highly lytic hepatitis, picornavirus
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.

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