Science Quiz / MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
A corona virus
a paramyxo virus
A hepadna virus
targetted by tamiflu
causes acute enteric infection and myelitis in the CNS
Used to deliver smallpox vaccine
subtype of herpes causing genital herpes
dsDNA virus replicating cytosolicly as contains transcription materials in virion
Codes a viral EGF for cell stimulation
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
a picorna virus
associated with cervical cancer
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
targetted by aciclovir/acyclovir
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
Successfully targetted by interferon therapy
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
Main example of an orthomyxovirus
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
codes Fc receptor molecules to evade antibody response
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
causes contagious neoplastic disease in chickens
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
causes common cold and susceptibility to secondary infection
persistent infection causing common warts or genital warts or genital warts
faeco-oral transmitted infection targetted by a killed vaccine
related to measles and resp syncytial virus, entering via resp tract
Enter best matching virusVirus
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
causes bronchitis, recent talk of vaccine
causes membrane modification
Codes ribonucleotide reducing enzymes (produces dNTP)
targetted by a sialic acid analogue
causes burkitt's lymphoma and glandular fever
acute in b cells and latent in memory b cells
causes a highly lytic hepatitis, picornavirus
papova virus causing experimental rodent tumors
systemic infection spread along blood/lymph/nerve tracts
Toga/flavi virus, classical version of recent pandemic
subtype of herpes causing cold sores
Generally infectious as M-tropic, mutating to T-tropic later
Codes soluble interferon receptors
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
encephalitis causing toga/flavi virus
a rhabdo virus
causes Kaposi's sarcoma
can cause congenital malformation thus vaccinated against
zoonotic systemic and cns infection, high morbidity
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
Can induce cell transformation
A calci virus, responsible for winter vomiting disease
a reo virus - causes infantile diarrhoea, superficial and acute
bullet shaped helical capsid
a toga/flavi virus causing acute and chronic hepatitis

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