Science Quiz / MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
persistent infection causing common warts or genital warts or genital warts
causes membrane modification
faeco-oral transmitted infection targetted by a killed vaccine
A calci virus, responsible for winter vomiting disease
encephalitis causing toga/flavi virus
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
a toga/flavi virus causing acute and chronic hepatitis
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
related to measles and resp syncytial virus, entering via resp tract
subtype of herpes causing genital herpes
acute in b cells and latent in memory b cells
targetted by a sialic acid analogue
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
Retrovirus
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
A hepadna virus
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
dsDNA virus replicating cytosolicly as contains transcription materials in virion
associated with cervical cancer
causes acute enteric infection and myelitis in the CNS
Codes ribonucleotide reducing enzymes (produces dNTP)
a picorna virus
Codes soluble interferon receptors
a rhabdo virus
Used to deliver smallpox vaccine
Enter best matching virusVirus
causes common cold and susceptibility to secondary infection
causes bronchitis, recent talk of vaccine
a paramyxo virus
causes contagious neoplastic disease in chickens
Main example of an orthomyxovirus
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
codes Fc receptor molecules to evade antibody response
Successfully targetted by interferon therapy
causes Kaposi's sarcoma
papova virus causing experimental rodent tumors
causes burkitt's lymphoma and glandular fever
systemic infection spread along blood/lymph/nerve tracts
Codes a viral EGF for cell stimulation
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
A corona virus
causes a highly lytic hepatitis, picornavirus
bullet shaped helical capsid
targetted by tamiflu
targetted by aciclovir/acyclovir
Toga/flavi virus, classical version of recent pandemic
zoonotic systemic and cns infection, high morbidity
a reo virus - causes infantile diarrhoea, superficial and acute
Can induce cell transformation
Generally infectious as M-tropic, mutating to T-tropic later
subtype of herpes causing cold sores
can cause congenital malformation thus vaccinated against

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