Science Quiz / MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
A hepadna virus
causes bronchitis, recent talk of vaccine
papova virus causing experimental rodent tumors
persistent infection causing common warts or genital warts or genital warts
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
causes a highly lytic hepatitis, picornavirus
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
bullet shaped helical capsid
related to measles and resp syncytial virus, entering via resp tract
Retrovirus
subtype of herpes causing genital herpes
a picorna virus
a paramyxo virus
faeco-oral transmitted infection targetted by a killed vaccine
Generally infectious as M-tropic, mutating to T-tropic later
causes acute enteric infection and myelitis in the CNS
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
Codes ribonucleotide reducing enzymes (produces dNTP)
acute in b cells and latent in memory b cells
can cause congenital malformation thus vaccinated against
A corona virus
targetted by aciclovir/acyclovir
causes contagious neoplastic disease in chickens
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
dsDNA virus replicating cytosolicly as contains transcription materials in virion
causes Kaposi's sarcoma
Codes soluble interferon receptors
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
Enter best matching virusVirus
associated with cervical cancer
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
targetted by a sialic acid analogue
subtype of herpes causing cold sores
Toga/flavi virus, classical version of recent pandemic
causes burkitt's lymphoma and glandular fever
codes Fc receptor molecules to evade antibody response
causes membrane modification
Used to deliver smallpox vaccine
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
Successfully targetted by interferon therapy
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
causes common cold and susceptibility to secondary infection
a toga/flavi virus causing acute and chronic hepatitis
a reo virus - causes infantile diarrhoea, superficial and acute
targetted by tamiflu
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
systemic infection spread along blood/lymph/nerve tracts
encephalitis causing toga/flavi virus
zoonotic systemic and cns infection, high morbidity
Codes a viral EGF for cell stimulation
a rhabdo virus
A calci virus, responsible for winter vomiting disease
Main example of an orthomyxovirus
Can induce cell transformation
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)

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