Science Quiz / Medical Microbiology Drugs (Antibacterial)

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Can you name the Medical Microbiology Drugs?

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HintAnswerExtra Info.
Penicillins are in which class of drugs?These are inhibitors of cell wall synthesis.
What are penicillins used to treat?Staph. and Strep. are examples.
Name a natural penicillin
Name an amino penicillin
Name one penicillin that is penicillinase resistant
Name an anti-Pseudomonal penicillin
Cephalosporins are in which class of drugs?These are inhibitors of cell wall synthesis.
How many generations of cephalosporins are there?
Which generation treats most Gram negatives, Pseudomonas aeruginosa, and Gram positive cocci?
Carbapenems are in which class of drugs?These are inhibitors of cell wall synthesis.
Which carbapenem is a substrate for DHP-1?Must be given with a DHP-1 inhibitor
Name a carbapenem that is not DHP-1 sensitive?
Monobactams are in which class of drugs?These are inhibitors of cell wall synthesis.
What is the only commercially-available monobactam?
Which beta-lactam class is used for cephalosporin-resistant Enterobacteriaceae, polymicrobial infections, and anaerobes?
Which beta-lactam class is not active against anaerobes or Gram positive organisms?
Vancomycin and Teicoplanin are in which class of drugs?These are inhibitors of cell wall synthesis.
What are Vancomycin and Teicoplanin used to treat?Used as a drug of last resort (MRSA and pseudomembranous colitis)
Bacitracin is in which class of drugs?These are inhibitors of cell wall synthesis.
Bacitracin is a topical antibacterial against what?
Which topical bacitracin-containing product is mentioned in the notes?
Which step of protein synthesis do aminoglycosides block?
Name a natural aminoglycoside
Aminoglycosides block the formation of what specifically?
What is gentimicin used to treat?
What is streptomycin used to treat?
What is spectinomycin used to treat?
What are aminoglycosides used for in general?
HintAnswerExtra Info.
Which aminoglycoside is used topically?Used in triple antibiotic ointment
Which step of protein synthesis do oxazolidinones block?
Name one thing that oxazolidinones are used to treat
Which step of protein synthesis do tetracyclines block?
Which tetracycline is short-acting?
Which tetracycline is active against most tetracycline-resistant strains?
Name a long-acting tetracycline that is not active against tetracycline-resistant strains
Tetracyclines are not bacteriocidal, but rather _____________Inhibits growth
What are tetracyclines used to treat?Broadest spectrum of all antibiotics
Tetracyclines are contraindicated in pregnant women and children under what age?Stains teeth brown/Harms fetal bone development
Which step of protein synthesis does chloramphenicol block?
What is chloramphenicol used to treat?Second-line therapy, Bacteriostatic
What is chloramphenicol used to treat in areas of poverty?
Which step of protein synthesis do macrolides prevent?
Which macrolide has a 14 member lactone ring?
Which macrolide has a 15 member lactone ring?
How do macrolides stimulate dissociation of peptidyl tRNA?
What are macrolides used to treat?Alternative to penicillin
Which macrolide causes the most GI upset?
Which macrolide is more active against Gram negative enterics?
Which macrolide is more active against Gram positives?
Which step of protein synthesis do lincosamides prevent?
What are lincosamides modified to for oral delivery?
Name one thing that clindamycin is used to treatPseudomembranous colitis is a possible complication
Which step of protein synthesis do ketolides prevent?
What is the only ketolide mentioned in the notes?
Do ketolides bind with higher or lower affinity than macrolides?
What are ketolides used to treat?Not used against enterics
HintAnswerExtra Info.
Which step of protein synthesis do streptogramins prevent?
Which streptogramin blocks peptide transfer?Synergistic with Type B streptogramins
Which streptogramin increases dissociation of peptidyl-tRNA?Synergistic with Type A streptogramins
Are streptogramins active against Gram positive bacteria?
Are streptogramins active against some, none, or all Gram negatives?Also used for vancomycin resistant Enterococcus faecium and bone and joint MRSA infections
Which class of drugs blocks DNA replicationInhibitor of nucleic acid synthesis
Name a quinolone
Quinolones block DNA gyrase. What does DNA gyrase cause?
Name a Gram negative agent that quinolones are active againstAlso treats Staph. and Strep., intracellular, wall-less, and anaerobes.
Which class of drugs blocks RNA transcription?Inhibitor of nucleic acid synthesis
Name one type of meningitis that rifamycins treatAlso treats Gram positive bacteria
What else do rifamycins treat?Also treats Gram positive bacteria
What do sulfonamides block?
Which sulfonamide is short-acting?Used with erythromycin for UTI's
Which sulfonamide is medium-acting?Used with trimethoprim for UTI's
Which sulfonamide is long-acting?Used with pyrimethamine for Plasmodium falciparum
Which sulfonamide is GI tract-limited?Used for ulcerative colitis
Which sulfonamide is used topically?Used for conjunctivitis
What does trimethoprim block?
What is trimethoprim used for?NOT Pseudomonas aeruginosa
Which drug is often used with trimethoprim?
Lipopeptides inhibit what?
Lipopeptides are used to treat organisms resistant to what?
Polymycins inhibit what?
What are polymycins used to treat?If resistant to multiple drugs
What is methenamine used against?Prophylaxis
 

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