Science Quiz / Drugs used for GI diseases

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Can you name the Drugs used for GI diseases?

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HintDrugcategory
Inhibits DHFR, treats Crohn's diseaseInflammatory bowel disease
Aminosalicylate, sulfapyridine is a breakdown product by bacteria that contributes to the drug's side effectsInflammatory bowel disease
PGE1 analogue, increases chloride rich fluid which promotes bowel movementProkinetic
Irreversibly inactivates H+/K+ ATPase of the parietal cells, side effects: decreased vit B12, increased serum gastrinPeptic ulcer
Competitively inhibits the parietal histamine (H2) receptor, side effects: gynecomastia, impotence, galactorrheaPeptic ulcer
Serotonin 5-HT receptor agonistLaxative
Most potent histamine receptor (H2) blockerPeptic ulcer
Absorbant of bacteria, toxins, and fluid, naturally occuring Mg Al silicateAntidiarrheal agent
Binds to and activates GABA receptorAntiemetic
Bulk forming, synthetic fibersLaxative
Simulates motilin receptors, macolideProkinetic
Stool surfactant agent (softener)Laxative
Dopamine receptor antagonistAntiemetic
Dissolves gallstonesTherapy for gallstones
Histamine (H1) antagonistAntiemetic
Coats ulcers and erosions, side effect: black stoolMucosal protective agent
Opioid receptor agonist, does not cross BBBAntidiarrheal agent
Cholinomimetic, directly stimulates M3 receptorsProkinetic
Cholinomimetic, cholinesterase inhibitorProkinetic
Forms a viscous paste that selectively binds to ulcers or erosionsMucosal protective agent
Analog of somatostatinAntidiarrheal agent
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, diarrheaPeptic ulcer
GlucocorticoidsInflammatory bowel disease
HintDrugcategory
Antipsychotic, inhibits dopamine and muscarinic receptors with antihistamine activityAntiemetic
Anti-tnf monoclonal antibody, side effects: infection, hepatic failureInflammatory bowel disease
Purine analog, low TPMT enzyme increases risk of bone marrow suppressionInflammatory bowel disease
Neurokinin receptor antagonistAntiemetic
PGE1 analogue, inhibitor of histamine, side effect: abortifacantMucosal protective agent
Analog of THC from marijuanaAntiemetic
AnticholinergicIrritable bowel syndrome
Osmotic laxative, increases stool liquiditiyLaxative
Blocks dopamine (D2) receptor, can cross BBB, side effects: high prolactin, extrapyramidal effectsProkinetic
Blocks dopamine (D2) receptor, does not cross BBBProkinetic
Stimulant laxative, anthraquinone derivative, chronic use leads to melanosis coli (brown colon)Laxative
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, constipationPeptic ulcer
Osmotic laxative, used for complete colon cleansingLaxative
Stimulant laxative, hydrolyzed in upper intestine to ricinoleic acidLaxative
Inhibits 5-HT3 receptor, used for diarrhea-predominant IBSIrritable bowel syndrome
Antipsychotic, central dopaminergic blockateAntiemetic
Absorbant of bacteria, toxins, and fluid, from applesAntidiarrheal agent
Opioid receptor agonist, crosses BBBAntidiarrheal agent
Bile salt binding resinAntidiarrheal agent
Bulk forming, natural plant productLaxative
5-HT3 receptor antagonist, used for chemotherapy induced nauseaAntiemetic
Muscarinic receptor antagonistAntiemetic

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