Science Quiz / Drugs used for GI diseases

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Can you name the Drugs used for GI diseases?

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HintDrugcategory
Muscarinic receptor antagonistAntiemetic
Bile salt binding resinAntidiarrheal agent
Antipsychotic, inhibits dopamine and muscarinic receptors with antihistamine activityAntiemetic
Antipsychotic, central dopaminergic blockateAntiemetic
Anti-tnf monoclonal antibody, side effects: infection, hepatic failureInflammatory bowel disease
Simulates motilin receptors, macolideProkinetic
Blocks dopamine (D2) receptor, can cross BBB, side effects: high prolactin, extrapyramidal effectsProkinetic
Purine analog, low TPMT enzyme increases risk of bone marrow suppressionInflammatory bowel disease
Dissolves gallstonesTherapy for gallstones
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, constipationPeptic ulcer
Competitively inhibits the parietal histamine (H2) receptor, side effects: gynecomastia, impotence, galactorrheaPeptic ulcer
Coats ulcers and erosions, side effect: black stoolMucosal protective agent
Dopamine receptor antagonistAntiemetic
Inhibits 5-HT3 receptor, used for diarrhea-predominant IBSIrritable bowel syndrome
Bulk forming, synthetic fibersLaxative
Stimulant laxative, hydrolyzed in upper intestine to ricinoleic acidLaxative
Bulk forming, natural plant productLaxative
Absorbant of bacteria, toxins, and fluid, from applesAntidiarrheal agent
AnticholinergicIrritable bowel syndrome
Binds to and activates GABA receptorAntiemetic
Analog of THC from marijuanaAntiemetic
Cholinomimetic, directly stimulates M3 receptorsProkinetic
Aminosalicylate, sulfapyridine is a breakdown product by bacteria that contributes to the drug's side effectsInflammatory bowel disease
HintDrugcategory
Osmotic laxative, increases stool liquiditiyLaxative
PGE1 analogue, inhibitor of histamine, side effect: abortifacantMucosal protective agent
GlucocorticoidsInflammatory bowel disease
Opioid receptor agonist, crosses BBBAntidiarrheal agent
Stimulant laxative, anthraquinone derivative, chronic use leads to melanosis coli (brown colon)Laxative
Inhibits DHFR, treats Crohn's diseaseInflammatory bowel disease
Most potent histamine receptor (H2) blockerPeptic ulcer
Blocks dopamine (D2) receptor, does not cross BBBProkinetic
Histamine (H1) antagonistAntiemetic
Opioid receptor agonist, does not cross BBBAntidiarrheal agent
Absorbant of bacteria, toxins, and fluid, naturally occuring Mg Al silicateAntidiarrheal agent
Cholinomimetic, cholinesterase inhibitorProkinetic
Analog of somatostatinAntidiarrheal agent
Forms a viscous paste that selectively binds to ulcers or erosionsMucosal protective agent
Irreversibly inactivates H+/K+ ATPase of the parietal cells, side effects: decreased vit B12, increased serum gastrinPeptic ulcer
Neurokinin receptor antagonistAntiemetic
5-HT3 receptor antagonist, used for chemotherapy induced nauseaAntiemetic
Serotonin 5-HT receptor agonistLaxative
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, diarrheaPeptic ulcer
PGE1 analogue, increases chloride rich fluid which promotes bowel movementProkinetic
Stool surfactant agent (softener)Laxative
Osmotic laxative, used for complete colon cleansingLaxative

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