Science Quiz / Drugs used for GI diseases

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Can you name the Drugs used for GI diseases?

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HintDrugcategory
Most potent histamine receptor (H2) blockerPeptic ulcer
Serotonin 5-HT receptor agonistLaxative
AnticholinergicIrritable bowel syndrome
Simulates motilin receptors, macolideProkinetic
Muscarinic receptor antagonistAntiemetic
Competitively inhibits the parietal histamine (H2) receptor, side effects: gynecomastia, impotence, galactorrheaPeptic ulcer
Bile salt binding resinAntidiarrheal agent
Opioid receptor agonist, does not cross BBBAntidiarrheal agent
5-HT3 receptor antagonist, used for chemotherapy induced nauseaAntiemetic
Bulk forming, synthetic fibersLaxative
Dissolves gallstonesTherapy for gallstones
Blocks dopamine (D2) receptor, can cross BBB, side effects: high prolactin, extrapyramidal effectsProkinetic
Coats ulcers and erosions, side effect: black stoolMucosal protective agent
Purine analog, low TPMT enzyme increases risk of bone marrow suppressionInflammatory bowel disease
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, constipationPeptic ulcer
Irreversibly inactivates H+/K+ ATPase of the parietal cells, side effects: decreased vit B12, increased serum gastrinPeptic ulcer
Absorbant of bacteria, toxins, and fluid, from applesAntidiarrheal agent
Inhibits DHFR, treats Crohn's diseaseInflammatory bowel disease
Cholinomimetic, directly stimulates M3 receptorsProkinetic
Cholinomimetic, cholinesterase inhibitorProkinetic
Anti-tnf monoclonal antibody, side effects: infection, hepatic failureInflammatory bowel disease
Opioid receptor agonist, crosses BBBAntidiarrheal agent
GlucocorticoidsInflammatory bowel disease
HintDrugcategory
Antipsychotic, central dopaminergic blockateAntiemetic
Aminosalicylate, sulfapyridine is a breakdown product by bacteria that contributes to the drug's side effectsInflammatory bowel disease
Analog of THC from marijuanaAntiemetic
PGE1 analogue, inhibitor of histamine, side effect: abortifacantMucosal protective agent
Neurokinin receptor antagonistAntiemetic
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, diarrheaPeptic ulcer
Stool surfactant agent (softener)Laxative
Stimulant laxative, hydrolyzed in upper intestine to ricinoleic acidLaxative
Inhibits 5-HT3 receptor, used for diarrhea-predominant IBSIrritable bowel syndrome
Absorbant of bacteria, toxins, and fluid, naturally occuring Mg Al silicateAntidiarrheal agent
Stimulant laxative, anthraquinone derivative, chronic use leads to melanosis coli (brown colon)Laxative
Binds to and activates GABA receptorAntiemetic
Blocks dopamine (D2) receptor, does not cross BBBProkinetic
Dopamine receptor antagonistAntiemetic
Osmotic laxative, increases stool liquiditiyLaxative
Forms a viscous paste that selectively binds to ulcers or erosionsMucosal protective agent
Analog of somatostatinAntidiarrheal agent
Histamine (H1) antagonistAntiemetic
Osmotic laxative, used for complete colon cleansingLaxative
Antipsychotic, inhibits dopamine and muscarinic receptors with antihistamine activityAntiemetic
PGE1 analogue, increases chloride rich fluid which promotes bowel movementProkinetic
Bulk forming, natural plant productLaxative

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Created Feb 11, 2012ReportNominate
Tags:drug, medication, medicine, usmle

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