Science Quiz / Drugs used for GI diseases

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Can you name the Drugs used for GI diseases?

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Stimulant laxative, anthraquinone derivative, chronic use leads to melanosis coli (brown colon)Laxative
Dissolves gallstonesTherapy for gallstones
Bulk forming, synthetic fibersLaxative
Muscarinic receptor antagonistAntiemetic
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, constipationPeptic ulcer
PGE1 analogue, increases chloride rich fluid which promotes bowel movementProkinetic
Forms a viscous paste that selectively binds to ulcers or erosionsMucosal protective agent
Most potent histamine receptor (H2) blockerPeptic ulcer
Opioid receptor agonist, does not cross BBBAntidiarrheal agent
Histamine (H1) antagonistAntiemetic
5-HT3 receptor antagonist, used for chemotherapy induced nauseaAntiemetic
Blocks dopamine (D2) receptor, can cross BBB, side effects: high prolactin, extrapyramidal effectsProkinetic
Neurokinin receptor antagonistAntiemetic
Opioid receptor agonist, crosses BBBAntidiarrheal agent
Anti-tnf monoclonal antibody, side effects: infection, hepatic failureInflammatory bowel disease
Inhibits 5-HT3 receptor, used for diarrhea-predominant IBSIrritable bowel syndrome
Competitively inhibits the parietal histamine (H2) receptor, side effects: gynecomastia, impotence, galactorrheaPeptic ulcer
Coats ulcers and erosions, side effect: black stoolMucosal protective agent
Inhibits DHFR, treats Crohn's diseaseInflammatory bowel disease
Analog of somatostatinAntidiarrheal agent
Antipsychotic, inhibits dopamine and muscarinic receptors with antihistamine activityAntiemetic
Bulk forming, natural plant productLaxative
Blocks dopamine (D2) receptor, does not cross BBBProkinetic
Purine analog, low TPMT enzyme increases risk of bone marrow suppressionInflammatory bowel disease
Stool surfactant agent (softener)Laxative
Aminosalicylate, sulfapyridine is a breakdown product by bacteria that contributes to the drug's side effectsInflammatory bowel disease
Bile salt binding resinAntidiarrheal agent
Osmotic laxative, increases stool liquiditiyLaxative
Absorbant of bacteria, toxins, and fluid, from applesAntidiarrheal agent
PGE1 analogue, inhibitor of histamine, side effect: abortifacantMucosal protective agent
Irreversibly inactivates H+/K+ ATPase of the parietal cells, side effects: decreased vit B12, increased serum gastrinPeptic ulcer
Cholinomimetic, cholinesterase inhibitorProkinetic
Cholinomimetic, directly stimulates M3 receptorsProkinetic
Antipsychotic, central dopaminergic blockateAntiemetic
GlucocorticoidsInflammatory bowel disease
Dopamine receptor antagonistAntiemetic
Stimulant laxative, hydrolyzed in upper intestine to ricinoleic acidLaxative
Serotonin 5-HT receptor agonistLaxative
Binds to and activates GABA receptorAntiemetic
AnticholinergicIrritable bowel syndrome
Absorbant of bacteria, toxins, and fluid, naturally occuring Mg Al silicateAntidiarrheal agent
Osmotic laxative, used for complete colon cleansingLaxative
Decreases intragastric acidity by reacting with HCl, side effects: belching, alkalosis, diarrheaPeptic ulcer
Simulates motilin receptors, macolideProkinetic
Analog of THC from marijuanaAntiemetic

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