Science Quiz / Anti HIV agents

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Can you name the Anti HIV drugs?

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Score 0/19 Timer 10:00
Given to pregnant womenPI
Blocks CCR5 co-receptorEntry inhibitor
Adverse reaction: skin rash; drug interactions: inhibits cyp3A4 and cyp2C9NNRTI
Adverse reactions: GI discomfort, rhinitis. Given once dailyPI
Blocks DNA strand transfer from viral to host genomeIntegrase inhibitor
Can cause severe, potentially fatal hepatotoxicityNNRTI
Inhibits and induces cyp3A4; adverse reactions: CNS toxicity, Gi intolerance, skin rashNNRTI
Avoid in patients with PKU, adverse reactions: pancreatitis, retinal changesNRTI
Most potent cyp3A4 inhibitor of the protease inhibitors. Used to prolong half life of other PIsPI
Contraindicated in patients with allergies to sulfanomidesPI
NucleoTIDE analogueNRTI
Prevents vertical transmission, adverse reactions: myelosuppression, gi intolerance, hematologic toxicity when given with ganciclovir or ribavirinNRTI
binds to and inhibits gp41 of HIVFusion inhibitor
Contraindicated in children, adverse reactions: hypersensitivity of palmsNRTI
Co-administration with TMP-SMZ increases bioavailabilityNRTI
Adverse reactions: jaundice, increased QT intervalPI
Adverse reaction: nephrolithiasis, patient must be adequately hydratedPI
Adverse reactions: hypersensitivity, increased risk of CVDNRTI
Adverse reaction: peripheral neuropathyNRTI

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