__, __, and __ that stay in the endomembrane compartment are made on the RER
__ occurs when molecules are placed into vesicles and discharged from the cell only when the cell receives a specific stimulus (signal).
SRP binding temporarily stops any further ___ ___
The SER is extensively developed in __, __, and __
Once the complex of __ binds to the ER, the SRP detaches from the SRP receptor.
_ and _ have signal sequences that allow the nascent peptides to enter the lumen of the RER for transport via vesicles to membrane-bound organelles and the plasma membrane.
The _ is a protein-lined channel in the ER membrane through which the nascent peptide can pass
Proteins that are going to be _ proteins or _ proteins are going to be made on the RER and enter into the _ of the RER
The RER is characterized by having __ on its surface.
The first few __ being made from the mRNA decide that proteins will be made on free ribosomes or on RER
_ and _ are inserted into new membranes as they are being formed inthe Er and then are used to form _ for virtually all of the sub-cellular organelles.
Glycosyltransferases transfer a specific sugar from a _ sugar to the growing end of the _ chain
As the integral membrane is made, it passes into the _
Encompasses those subcellular structures that are membrane bound and participate in production and delivery of materials within the cell and to the exterior of the cells.
The RER is highly secretory cells is located at the __ level near the blood supply andthe secretory vesicles at the __ end where they can release their contents extracellularly.
The __ lies just above the RER
The signal sequence contains _ to _ hydrophobic amino acids
The signal sequence of the nascent peptide inserts into the _ and the pore opens
The SRP binds to a SRP receptor and the ribosome binds to a _.
When oligosaccharides are attached to the modified, _ of the glucoses are removed
Phospholipids can be transported through the cytoplasm by _ to other organelles
Once the oligosaccharides are attached to the polypeptide, they get _
The __ moves stuff out of the cell.
The ___ is associated with the production of proteins, carbohydrates and lipids and encompasses various pathways taking materials to the plasma membrane, and to the Golgi complex,
Phospholipids of one membrane are transferred to another membrane by _ proteins
Movements of __ in the cytoplasm are targeted to go to specific sites.
Glycosylated protein have a total of _ glucoses removed and when this happens _ are released
If you look at the two lipid bilayers, the phospholipids are _. This is established in the _
Phospholipid heads are modified enzymatically in the _
Answer
Question
O-linked oligosaccharides are put in the _
Newly made phospholipids are carried to the _ _ in 'budded' vesicles
Completed oligosaccharide is transferred as a block to the _ while the nascent protein is entering the _
When the _ region of the polypeptide gets into the translocon, it can move _ in the lipid bilayer through a _ gate inthe side of the translocon
If glycosylation continuously fails, degradation of protein is called _
Folding of the polypeptide and formation of disulfide bonds through the cysteine residues completes the _ structure of the polypeptide
_ is critical for intermolecular interactions and for proper folding of proteins
Phospholipids of one type can concentrate in the area where a _ will form
The main intracellular pathways in cells include the ___ and an ____
RER is a network of __, or flattened sacs and is continuous with the __ which also has ribosomes on its cytoplasmic side.
The SRP binds to the signal sequence of the _ polypeptide and to the _
Sugars and their order and accomplished by a family of membrane-bound enzymes called
Polypeptides in RER may have _ residues in the reduced state
If a protein does not pass inspection from chaperones, a glucose is (added/removed) to the oligosaccharide, and reinspection occurs
Phospholipids are made on the _ side of the ER by _ proteins
The orientation of transmembrane proteins is for the more positive end of the polypeptide to be exposed to the _
A ___ moves to an ___, fuses with it and transfers its cargo
The SRP binds to the _ side of the RER
_ are modified as they move from the ER to other parts of the cell.
Materials are shunted from one membrane compartment to another on tracks and are moved by ____.
List 5 cystolic proteins made on free ribosomes floating around in the cytosol
_ and _ get completed in the Golgi complex
When the translocon is inactive there is a small __ plugging it, inhibiting passage of calcium and other ions between the _ and the _ of the ER.
Highly secretory have (more/less) RER than non-secretory cells
Ribosomes on the RER produce _ and _
Sequence of adding sugards for N-linked oligosaccharides
All __ are essentially identical and can be used to make cystolic proteins or proteins made on the RER
The ___ is highly curved and tubular and traverses the cytoplasm.
The _ side of the membrane buds will be found on the _ of the target membrane.
Answer
Question
Only _ linked oligosaccharides are placed on polypeptides in the RER
Disulfide bonds are made between the _ by the enzyme _.
Most of the time the signal sequence is at the _ terminus of the nasenct peptide but sometimes it can be near the _ of the growing polypeptide
In the lumen of the RER there are numerous _ and _
_ molecules examine glycosylated protein for quality control
RER and SER are __ with each other.
RER is especially well developed in cells that are highly __.
Almost all proteins made on the RER become _
The __ of the ER is seperated fromthe cytosol by the ER membranes and contains very different materials than in the cytosol.
For multiple spanning transmembrane proteins, the first _ transmembrane section will determine how it is orientated and subsequent transmembrane sections will oreint at _ degree an
In the translocon, there are _(#)_ (hydrophilic/hydrophobic) amino acids located at its narrowest point.
In producing the oligosaccharides to put on a polypeptide, the oligosaccharide is first constructed on a lipid molecule called _, which is embedded in the lipid bilayer
The kinds of sugars and their order is precise on _.
__ happens continuously, taking molecules to the plasma membrane.
Once the polypeptide formation is complete and the polypeptide is in the _ of the RER, the pore is _ .
A sequence of amino acids, called __ that, when being made as a nascent polypeptide, direct the ribosome to attach to the ER.
To be an integral membrane protein it has to have a _ region
Most _ _ are made entirely in the _
Some phospholipids are destined for the inner leaflet and are flipped by enzymes called
When the signal sequence is produced, it is recognized by a __ which is made up of six distinct poplypeptides and a small __ molecule of RNA.
When the _ terminus of the nascent peptide enters the _ of the RER, the signal is removed by the enzyme _ and _ are added to the polypeptide by the enzyme _
The arrangement of the sugars is dependent on the _ _ of the enzymes
_ have enzymes in them that can convert one phospholipid to another
All membranes arise from _ membranes
Ribosomes in the cytoplasm produce _, _, and _
Once attached, the signal sequences pass through the RER into the __ of the RER through a small channel
The __ moves stuff into the cell to various compartments.
Transport vesicles have 'addresses' and receive sorting signals that are located in the __ of the vesicles.
You're not logged in!
Compare scores with friends on all Sporcle quizzes.
Get the best of Sporcle when you Go Orange. This ad-free experience offers
more features, more stats, and more fun while also helping to support Sporcle. Thank you for
becoming a member.
In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.
Show Comments