Science Quiz / CNS Biochem

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Can you name the CNS Biochem

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HintAnswer
Huntington's disease/ area
Gene?
Chromosome?
What's wrong with the gene?
Inheritance pattern?
Morphological feature? /Huntington
MS/ full name?
Gene?
Pathogenesis?
Macrophage feature?
Charcot's Triad? 1?
2?
3?
Humanized monoclonal antibodies treatment?
Immunomodulatory treatment?/MS
ALS/ Full name?
Aka?
Gene?
Pathogensesis
Treatment?
HintAnswer
Bulbar onset percentage?
Spinal onset percentage?
Any cognitive impairment?
Who got this disease? /ALS
Parkinson's/ Area
Gene? (2)
Parkin work with another enzyme called?
Alpha-synuclein locus?
Alpha-synuclein normal function?
Alpha-synuclein inclusion bodies? /Parkinson's
AD/ Full name?
Precursor to Beta-amyloid?
What turns the precursor into beta-amyloid?
What breaks down beta-amyloid?
Which ApoE isoform is the weakest in breaking beta- amyloid?
What is the gene affecting gamma-secretase
Beta-amyloid forms?
Postmortem staging concerning Tau fragment/ Neurofibrillary tangles extensiveness
Amyloid plaque can cause intracranial haemorrhage by?
Down syndrome is related to which gene?

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