Science Quiz / Cholinergic agonists

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Can you name the Cholinergic agonists?

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Clinical UseAdverse effects/Other
Treats flaccid abdomen, urinary retention; direct actingIncreases parasympathetics (bronchoconstriction, excessive sweating, drooling)
Treats acute glaucoma (constricts pupil); direct actingIncreases parasympathetics (bronchoconstriction, excessive sweating, drooling)
Used for smoking cessation; direct actingAt high doses, inhibits nicotinic receptors via depolarizing blockage
Treatment for Alzheihmer's; indirect, reversible
Used to distinguish cholingeric crisis vs. myasthenia gravis; indirect, reversibleVery short acting, lasts 5-10 minutes
Treats Myasthenia Gravis; indirect, reversibleMedium acting, 3-6 hours, doesn't cross BBB
Treats Myasthenia Gravis, antidote for tubocurarine (NMJ blocker) overdose; indirect, reversibleMedium acting, 3-6 hours, doesn't cross BBB
Antidote for Atropine overdose; indirect, reversiblecrosses BBB
Treats chronic glaucoma, decreases secretions; indirect, irreversibleCan cause cholinergic crisis, long acting (8 days)
Antidote to echothiophate cholinergic crisismust be initiated within first hour
N/ACan cause convulsions, coma, respiratory arrest

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