Science Quiz / Hematology

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Hematology

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Most common causes of schistocytes on the PBS?
 
 
 
 
Most common cause of normocytic anemia?
 
 
 
 
 
 
Most common cause of macrocytic anemia?
 
 
 
Most common causes of microcytic anemia?
 
 
 
 
 
What is polycythemia? What is the differential?
 
 
 
 
 
 
What are the causes of thrombocytosis?
 
 
 
 
What is the classic triad and pentad of HUS and TTP, respectiely?
 
 
 
 
 
What is the pathogenesis of TTP/HUS?
 
Treatment for HUS
 
Microcytic + Target Cells =
 
Normocytic + Target Cells =
 
Macrocytic + Target Cells =
 
Most common cause of Echinocytes(burr cells) on PBS?
 
 
Normal Serum Fe, Normal TIBC, Increased BM Fe
 
Bright red skin + Hb of 20 =
 
Long-term effects of B12 deficiency
 
What structure is affected from this disease?
 
What helminth can cause this disease?
 
Bone marrow expansion is seen with:
 
Which type of cancer are patients w/ pernicious anemia at increased risk for?
 
What is the CP of ALL?
 
 
 
Most common childhood cancer?
 
Loss of 3 alpha genes?
 
Loss of 4 alpha genes?
 
Causes of coarse basophilic stippling? (TAIL)
 
 
 
 
DIC(Increased, Increased, Increased, Decreased)
 
 
 
 
Increased HbF
 
Increased HbA2
 
Primary poycythemia rubra vera(Increased, Decreased, Mutation)
 
 
 
Decreased Serum Fe, Decreased TIBC, Increased BM Fe
 
Secondary polycythemia rubra vera(Increased, Increased)
 
 
Reactive/relative polycythemia
 
Neutropenia(#, susceptible...)
 
 
 
 
Neutrophilia(#, caused by)
 
 
Lymphocytosis(#, caused by)
 
 
Eosinophilia(#, caused by...)
 
 
 
 
 
Monocytosis(#, caused by...)
 
 
 
Basophilia(#, disease caused)
 
 
Dohle Bodies(toxic granules in PMNs)
 
Bad DNA repair mechanism -> congenital abnormalities(no thumb/radii)
 
Reactive Lymphocytes
 
< 15 yo
 
15 - 40
 
40 - 60
 
> 60
 
 
 
 
Myeloperoxidase stain for:
 
Terminal deoxynucleotide transferase (Tdt) stain for:
 
CD 1-8
 
CD 19-23
 
Massive Splenomegaly
 
 
 
Leukocytosis from stress/infection
 
t(8;14)
 
t(9;22)
 
t(11;14):Cyclin D1
 
t(14;18)
 
t(15;17)
 
Treatment of AML M3(Vitamin A)
 
AML M5 major symptom
 
Ringed sideroblasts(what, where, stain)
 
 
 
JAK2 mutation
 
 
 
Burkitts lymphoma genes
 
 
Primary myelofibrosis symptoms
 
 
 
Hairy Cell Leukemia (HCL) symptoms(OPS)
 
 
 
Multiple Myeloma symptoms
 
 
Decreased Serum Fe, Increased TIBC, No BM Fe
 
Bence-Jones proteinuria(Most to least)
 
 
 
Multiple Myeloma PBS
 
Free Ig light chain deposited in tissue
 
Lymphoma in teens/20s
 
Most common form of non-Hodgkin's lymphoma
 
Starry sky node pattern(dx, stars, sky)
 
 
 
Floret lymphocytes
 
Pautrier micro-abscesses
 
Reed-Sternberg Cells
 
Bone marrow Tdt(+) in kids
 
Increased Serum Fe, Decreased TIBC, Increased BM Fe
 
CD15 and CD30
 
Anisocytosis(Thal minor) = different
 
Poikilocytosis(Thal minor) = different
 
Howell-Jolly bodies
 
Pappenheimer bodies(lysosome)
 
Heinz bodies(what, caused by...)
 
 
 
Codocytes
 
Drepanocytes
 
Hypersegmented neutrophils
 
Pernicious Anemia
 
 
Duodenum
 
Jejunum
 
Ilium
 
Iron deficiency until proven otherwise
 
Iron deficiency anemia(Decreased, Increased)
 
 
Pure red cell aplasia
 
Hereditary spherocytosis defect in:
 
 
PNH
 
 
PNH Presents as:
 
 
G6PD cells on PBS
 
 
Sickle cell mutation
 
Koionychias
 
HbC
 
 
 
Multiple Myeloma top 2 causes of death
 
 

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