Science Quiz / Dermatologic Diseases- FA 2017

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Can you name the Dermatologic Diseases- FA 2017?

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Benign capillary hemangioma of infancy, appears, grows rapidly and regresses by 5-8
Flat, greasy, pigmented epihtelial proliferation with keratin filled cysts (horn cysts)
Target lesions (target with multiple rings and dusky center w/ epithelial destruction)
Benign, painful, red blue tumor under fingernails, from modified smooth muscle cells of thermoregulatory body
Abnormal keratinocyte desquamation, propionibacterium acnes, colonization, comedomes
Raised inflammatory lesions of subcutaenous fat (panniculitis), anterior shins, idiopathic
Melanoma w/ dominant early radial phase
'herald patch' followed with scaly erythematous plaque in chirstmas tree distribution on trunk; collarette scale; self resolve in 6-8 weeks
Serum IgE, atopic disease
Melanoma w/ early vertical phase, pushes epidermis upward
Wickham striae (reticular white lines), hypergranulosis; Sawtooth infiltrate of lymphocytes at dermal-epidermal junction; 6P
6Ps are
Irregular, white, painless plaques on lateral tongue
Stevens Johnson w/ > 30%
Type IV HSN, exposure to allergen
Umbilicated papules; contagious
Koilocytosis, soft, tan colored, cauliflower like papules
Upper dermis and superficial lymphatic crusting; well demarcated
Endothelial malignancy of skin/mouth/GI/respiratory, HIV associated, lymphocytic infiltrate
S100 tumor marker; BRAF V600E Activating mutation; dpt depth of tumor; dysplastic nevi
Cavernous lymphangioma of neck, associated with Turners
Erythematous papule/pustule, no comedones, associated with flushing, potential scattered telangiectasias
IgG against desmoglein, acantholysis, row of tombstones, oral mucosa involved, Nikolsky+
Associated with infections, drugs, cancers, autoimmune disease (mycoplasma, HSV, phenytoin, sulfa drugs, beta lactams); macules, papules, vesicles
Associated with HepC
HintAnswer
SCC Variant that grows rapidly (4-6wks) and may regress spontaneously over months
Lesar Trelat sign
Benign capillary hemangioma of elderly, does not regress
Epidermal hyperplasia, hyperpigmented thickening of skin, esp in axilla/neck; associated with insulin resistance/visceral malignancy
Benign capillary skin papule in AIDS, neutrophilic infiltrate
Stratum granulosum attachment destruction, fever, erythematous rash, sloughing of upper layers, Nikolsky sign+
Melanoma along epi-derm junction
Herpetic whitlow
Polypoid lobulated capillary hemangioma that can ulcerate and bled, trauma and pregnancy
Small, rough, erythematous or brownish papules/plaques; inc SCC risk
Sloughing of skin at dermal epidermal junction; targetoid skin lesion; bullae and necrosis (10-30%)
Superficial skin infection, highly contagious, honey colored crusting
Melanoma of palm/sole; not associated with UV exposure
Excessive UV irradiation
Keratin pearls; Lower lip/face/ears/hands, locally invasive, ulcerative red lesions with frequent scale
Deeper dermis, subcutaneous tissue, break in skin/trauma
Blood vessel malignancy of head/neck/breast, associated with vinyl chloride, arsenic exposure, radiation therapy. Aggressive
Pruritic papules, vesicles, and bullae; deposits of IgA at dermal papillae
Pruritic wheals, superficial dermal edema and lymphatic channel dilation
Firm, hyperpigmented papules and pustules that are painful/pruritic, cheeks/jawline, neck
Deeper tissue injury from anaerobic bacteria, out of proportion pain, crepitus
Collection of pus in walled off infection
Upper lip; waxy pink pearly nodule; telangiectasias; rolled borders with central crusting/ulceration; palisading nuclei
Parakeratotic scaling with acanthosis, dec granulosum, munro microabcesses, Auspitz sign
IgG against hemidesmosomes, tense blisters w/ eosinophils, spare oral mucosa, linear pattern, Nikolsky-

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