Science Quiz / Dermatologic Diseases- FA 2017

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Can you name the Dermatologic Diseases- FA 2017?

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Flat, greasy, pigmented epihtelial proliferation with keratin filled cysts (horn cysts)
Endothelial malignancy of skin/mouth/GI/respiratory, HIV associated, lymphocytic infiltrate
Collection of pus in walled off infection
Pruritic wheals, superficial dermal edema and lymphatic channel dilation
Serum IgE, atopic disease
Benign, painful, red blue tumor under fingernails, from modified smooth muscle cells of thermoregulatory body
Firm, hyperpigmented papules and pustules that are painful/pruritic, cheeks/jawline, neck
Benign capillary skin papule in AIDS, neutrophilic infiltrate
Melanoma along epi-derm junction
Melanoma w/ early vertical phase, pushes epidermis upward
Melanoma w/ dominant early radial phase
Keratin pearls; Lower lip/face/ears/hands, locally invasive, ulcerative red lesions with frequent scale
Herpetic whitlow
Upper lip; waxy pink pearly nodule; telangiectasias; rolled borders with central crusting/ulceration; palisading nuclei
Upper dermis and superficial lymphatic crusting; well demarcated
Deeper tissue injury from anaerobic bacteria, out of proportion pain, crepitus
Lesar Trelat sign
Blood vessel malignancy of head/neck/breast, associated with vinyl chloride, arsenic exposure, radiation therapy. Aggressive
Benign capillary hemangioma of infancy, appears, grows rapidly and regresses by 5-8
Wickham striae (reticular white lines), hypergranulosis; Sawtooth infiltrate of lymphocytes at dermal-epidermal junction; 6P
S100 tumor marker; BRAF V600E Activating mutation; dpt depth of tumor; dysplastic nevi
Target lesions (target with multiple rings and dusky center w/ epithelial destruction)
Superficial skin infection, highly contagious, honey colored crusting
Stevens Johnson w/ > 30%
Parakeratotic scaling with acanthosis, dec granulosum, munro microabcesses, Auspitz sign
HintAnswer
Irregular, white, painless plaques on lateral tongue
Raised inflammatory lesions of subcutaenous fat (panniculitis), anterior shins, idiopathic
Type IV HSN, exposure to allergen
IgG against hemidesmosomes, tense blisters w/ eosinophils, spare oral mucosa, linear pattern, Nikolsky-
Melanoma of palm/sole; not associated with UV exposure
IgG against desmoglein, acantholysis, row of tombstones, oral mucosa involved, Nikolsky+
Sloughing of skin at dermal epidermal junction; targetoid skin lesion; bullae and necrosis (10-30%)
Koilocytosis, soft, tan colored, cauliflower like papules
Erythematous papule/pustule, no comedones, associated with flushing, potential scattered telangiectasias
Associated with HepC
Excessive UV irradiation
Abnormal keratinocyte desquamation, propionibacterium acnes, colonization, comedomes
Polypoid lobulated capillary hemangioma that can ulcerate and bled, trauma and pregnancy
Cavernous lymphangioma of neck, associated with Turners
Small, rough, erythematous or brownish papules/plaques; inc SCC risk
Pruritic papules, vesicles, and bullae; deposits of IgA at dermal papillae
Deeper dermis, subcutaneous tissue, break in skin/trauma
Benign capillary hemangioma of elderly, does not regress
Associated with infections, drugs, cancers, autoimmune disease (mycoplasma, HSV, phenytoin, sulfa drugs, beta lactams); macules, papules, vesicles
Stratum granulosum attachment destruction, fever, erythematous rash, sloughing of upper layers, Nikolsky sign+
6Ps are
Epidermal hyperplasia, hyperpigmented thickening of skin, esp in axilla/neck; associated with insulin resistance/visceral malignancy
Umbilicated papules; contagious
SCC Variant that grows rapidly (4-6wks) and may regress spontaneously over months
'herald patch' followed with scaly erythematous plaque in chirstmas tree distribution on trunk; collarette scale; self resolve in 6-8 weeks

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