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Lipid-Lowering Drugs - Statins Quiz Stats

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Hint Answer % Correct
Examples include __Atorvastatin, pravastatin & simvastatin
82.6%
Statins are __HMG CoA reductase inhibitors
56.5%
Statins reversibly inhibit the enzyme __HMG CoA reductase
56.5%
This catalyses the __ step in the synthesis of cholesterolRate-limiting
47.8%
HMG CoA becomes __, which becomes cholesterolMevalonic acid
34.8%
The decrease in cholesterol synthesis also increases the number of __, thus decreasing LDL levelsLDL receptors
34.8%
ContraindicationsPregnancy, breastfeeding, liver disease
26.1%
They can reduce the risk of dying from a coronary event by up to nearly __50%
17.4%
Adverse effectsReversible myositis (rare), constipation or diarrhoea, abdo pain, flatulence, nausea, headache, fatigue, insomnia, rash
17.4%
These have been shown to reduce blood cholesterol by up to __ in some patients35%
13%
Used for hyperlipidaemia resistant to dietary control, as part of secondary prevention in patients with serum cholesterol __Over 5.5
4.3%

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Created Dec 10, 2014ReportNominate
Tags:drug, station

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