Science Quiz / CSIM - Haemolytic anaemias

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Can you name the CSIM - Haemolytic anaemias

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HintAnswer
This is anaemia due to increased __
They occur when __ lifespan is reduced
Erythropoiesis can be increased __
Therefore __ may be compensated & not cause anaemia
Reduced red cell lifespan can be caused by __ or __ defects
It can occur within the circulation or be __
Extravascular haemolysis is the route by which red cells are normally broken down & occurs in the __ of the spleen, bone marrow & liver
HintAnswer
__ is the destruction of red cells within the circulation
It is characterised by the features of extravascular haemolysis as well as __ (Hb is released into the bloodstream)
Also absence of plasma __
__ (the Hb concencentration exceeds the tubular reabsorptive capacity & Hb is therefore excreted in the urine
__ (proximal tubule cells containing intracellular deposits of haemosiderin derived from the Hb reabsorbed in the kidneys are shed in the urine
__ (some of the Hb is oxidised & binds to albumin
__ (erythrocyte precursors enter the blood (also found in extravascular haemolysis

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