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Combination of coagultive and liquefaction necrosis
Cells that regenerate throughout life; ex, skin, mucosa, hematopoietic stem cells;
Don’t continuously divide but can when necessary; ex, prox. renal tubule, hepatocytes;
Very resistant to radiation, low levels of replicative capacity
Combined term of a mass of capillaries and fibroblasts;
masses seen in cirrhosis representing accumulation of intermediate prekeratin filaments;
Healing when there is little tissue damage and proximal wound edges
Healing where there is large tissue defects and the edges of the wound are not in contact
What degrades collagen?
Cells that contract to pull the edges of a wound together;
Macrophages present in the brain;
Seen with tissue damage characterized by broad/wide zones of basophilia;
Prominent scar that is localized to the wound
Characterized by excessive scar tissue beyond the edges of the wound
Can be administered to prevent expansion of fibrosis;
Necrosis generally the result of heterolytic digestion
Apoptotic hyaline masses among liver cells in acute massive hepatic necrosis;
IFN-γ transforms macrophages into an...
Multinucleated giant cell with haphazard arrangement of nuclei
Multinucleated giant cell with peripheral arrangement of nuclei
Clear area around representative of a large Golgi;
Name given to mast cells present in tissue
Granulated cell with a bi-lobed nucleus
Characterized by fine basophilic stippling around small blood vessels
IL-1, IL-8, and TNF are secreted by...
Produced by platelets and vascular endothelium;
Produced by vascular endothelium;
Deficiency of NADPH oxidase
Produces HOCl needed for bacterial killing
Defect in chemotaxis, giant granules present;
No enzymatic degradation of fat but release of fat from cells;
B4, IL-8, and C5a are important...
Defined as the increase number of cells in an organ or tissue
Hormonal or compensatory
Caused by excessive hormonal stimulation or GF acting on target cells
Defined as an increase in the size of cells
Caused by volume overload in the heart
Caused by pressure overload in the heart
Defined as shrinkage in size of cells, may lead to shrinkage of entire organ
A reversible change in which one adult cell type is replaced by another
Undigestible material
Most common cause of cell injury
Spherical hyaline masses within plasma cells;
Special tissue reaction in which the connective tissue stains highly eosinophilic like fibrin
Characterized by increased turgor and fine cytoplasmic vacuolization without nuclear displacement
Characterized by decreased turgor and large vacuoles with peripheral displacement of nuclei
Degeneration and condensation of nuclear chromatin
Nuclear fragmentation
Nuclear dissolution
Necrosis resulting from hypoxia/ischemia; predominantly autolytic
