Science Quiz / Plasma Glucose Regulation

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QuestionAnswer
percentage of alpha cells in the pancreas
These drugs act on the ATP dependent K channel to activate insulin secretion
insulin dependent transporter
T/F: Proinsulin is composed of 2 subunits.
insulin independent diabetes
T/F: Insulin's response to persistent hyperglycemia is characterized by a sharp initial increase in insulin secretion, then a fall and gradual rise in insulin (due to increase in i
insulin dependent diabetes
used as a measure of insulin secretion
these cells of the pancreas make glucagon
What other 2 molecules can be found in mature insulin granules besides insulin?
How much oral glucose is administered during a glucose tolerance test? (grams)
T/F: Insulin receptor is a tyrosine kinase receptor thats acts to autophosphorylate itself.
production of glucose from non-carbohydrate sources
low levels of glucose stimulates the release of _____.
Dr. Benting won the nobel prize for insulin in ____.
T/F: Acute hypoglycemia cause neurological problems, coma, and death because the brain is dependent upon glucose as a source of energy.
percentage of delta cells in the pancreas
T/F: Insulin is protein hormone and is synthesized from pro-insulin.
T/F: Glucose enters the cell via active transport.
This protein is important for the activation of glucose transport and it is phophorylated by the B subunit of the insulin receptor.
these cells of the pancreas make somatostatin
T/F: C peptide has no biological funtion.
GI hormones that are released in response to a meal containing glucose
QuestionAnswer
persistent hyperglycemia causes perisistent _______.
IRS mediates the translaocation of what glucose transporter to the cellular membrane?
Major targets of insulin include liver, _____ and _____
T/F: 98% of the pancreas has endocrine function.
insulin independent transporter
T/F: Chronic hyperinsulinemia causes a downregulation of insulin receptors due to an imbalance of receptor internalization and recycling.
percentage of beta cells in the pancreas
Muscle and adipocytes contain GLUT4.
Blood glucose levels must be maintained at ___mg/ 100ml.
T/F: Norepinephrine and epinephrine act to inhibit insulin release.
insulin deficiency causes a (an) _____ in plasma glucose
The B subunit of the insulin receptor acts to bind and recognize insulin.
The liver degrades ___% of the insulin released.
these cells of the pancreas make insulin
T/F: Hepatocytes contain GLUT4 transporters.
Currently used in the treatment of diabetes and they act by binding to their G-protein coupled receptor to increase intracellular Ca activating insulin release.
Normal blood glucose levels are ___mg/ dl
acetylcholine acts to _____ insulin secretion
T/F: Basal glucose levels in a diabetic patient are equivalent to non-diabetic patient.
In liver, glucose stimulates which enzyme?
T/F: Influx of glucose in a hepatocyte activates glucokinase which increase ATP levels, activating ATP dependent K channel. This causes a depolarization of the cell causing an incr
T/F: An increase in sympathetic activity, increases production and synthesis of insulin.

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Created Feb 27, 2012ReportNominate
Tags:concept, regulation

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