Science Quiz / GI Nervous System & Motility

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Can you name the GI Nervous System & Motility?

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QuestionAnswer
T/F: Sympathetic modulation of the distal GI tract occurs through the pelvic splanchnic nerves.
this plexus primarily controls the motility of the GI tract
stool frequenct of < 3 times per week
arresting the segmentation of the GI tract is known as what?
T/F: The change in the electrical potential of the interstitial cells of Cajal translate into the change of smooth muscle contraction of the GI tract.
are mesenchymal non-neuronal tissue of origin
has a transit time of 24-48 hours
This disorder is characterized by heartburn. Occurs due to HCl irritation of esophageal lining
T/F: Activation of nicotinic cholinergic receptors on the myenteric plexus enhance smooth muscle activity
cells that acts as mediators to modify motor signals among smooth muscle layers and neurons that control motility (submucosal and myenteric plexuses)
T/F; High fat diet, chocolate, peppermint, alcohol and smoking can cause an increase in occurence oif GERD.
2 inhibitory neurotransmitters that modulate function of the GI tract
During peristalsis, NO and VIP at _____ (upstream or downstream) of bolus to initiate contraction.
T/F: Substance P and acetylcholine act to modulate GI function by inducing hyperpolarization in the post-synaptic cells of the GI.
emesis =
Which 2 nervous controls are important for gastric accommodation?
this division of the CNS projects to the GI tract from the medulla and the sacral spinal cord
T/F: The Lower esophageal spincter is voluntarily controlled.
Vagovagal reflex from stomach that tells the small intestine to contract
name the 2 ganglia that have sympathetic control of the lower GI tract
reflex that occurs when there is something in your stomach and efferent signals tell the large intestine to initiate activity
Which hormone is responsible for inducing vomiting?
T/F: Substances move uniformly through the digestive tract,.
upper 3rd of the esophagus is made of ____ muscle
Which plexus is continuous throughout the GI tract?
T/F: Adaptive relaxation accounts for the stomach's ability to accommodate an increase in volume without a change in pressure.
the ____ control of the GI tract arises primarily from the superior cervical ganglion, celiac ganglion, superior and inferior mesenteric ganglia.
QuestionAnswer
sensory input from the stomach upto the emetic center of the brain occurs primarily via the ____ nerve.
Which layer of smooth muscle causes segmentation?
occurs when the lower esophageal sphincter fails to relax normally due to degeneration of the myenteric and/or dorsal motor nucleus or Vagus nerve
The gastrocolic reflex is mediated via which nerve (efferent limb)?
T/F: Rapid segmentation occurs at the distal end of the GI tract.
neurotransmitter of post ganglionic sympathetic fibers
a single continuous electrical wave that sweeps one way distally from the stomach that affects all muscles of the GI tract
T/F: The sympathetic nervous system provides a low tonic inhibition of the GI tract, while the parasympathetic has a large influence on promoting GI activity
parasympathetic control of the upper GI
T/F: The internal anal sphincter receives both sympathetic and parasympathetic innervation
How frequently does the MMC occur in the absence of food?
efferents of the vagus nerve arise from which nucleus
t/F: The esophagus, colon, and migrating motor complex have long peristaltic waves, while most peristaltic waves are short
Where is the MMC initiated?
sphincter important for the initiation of swallowing
Which cells release serotonin to induce vomiting?
neurotransmitter of post ganglionic parasympathetic fibers
When threshold is reached in the interstitial cells of Cajal, voltage gated ___ channels are opened, initiating depolarization, in the smooth muscle.
The signal from the interstitial cells of Cajal propagates to the smooth muscle cells through which intercellular junctions?
T/F the sympathetic nervous system promotes GI function, whereas the parasympathetic nervous system inhibits it.
only occurs in the absence of food
cells that serve as pacemaker cells,which regulate membrane potential of BER
T/F: The vasovagal reflex is important in gastric accommodation.
autonomous nervous sytem within the wall of the GI tract that controls secretions, motor activity, sphincters and blood vessels
the meissner's plexus is located in which layer of the GI tract wall?
Which structure maybe involved in dysphagia
chemoreceptor trigger zone is located in the ___ ventricle
QuestionAnswer
T/F: Although the enteric nervous system can act autonomously, the central nervous system acts to modulate the activity of the GI tract.
difficulty swallowing
Gastroesophageal Reflus disease occurs because of dysfunction to which structure?
Has a transit time of 1 to 5 hours
medical term for inability to swallow
reflex arc that involves vagus as the afferent input to the CNS as well as the output to enteric nervous system
Which receptor for serotonin is involved in the vomiting response?
stool frequency of > 3 times pre day
spinal root levels of the parasympathetic control of the lower GI
located between the circular and longitudinal smooth muscle layers
The pelvic splanchnic nerves cause contraction of the longitudinal smooth muscle layer and relaxtion of the internal anal sphincter through which type of cholinergic receptor?
T/F: activation of the enterochromaffin cells leads to release of serotonin which causes the vomiting reflex
/The hypogastric nerve causes _____ (contraction or relaxation) of the internal anal sphincter through a adrenergic receptors.
During peristalsis, acetylcholine and substance P at _____ (upstream or downstream) of bolus to initiate contraction.
2 excitatory neurotransmitters that modulate function of the GI tract
contraction of this layer of smooth muscle causes a decrease in diameter of the lumen of the GI
What hormone is involved in initiating the MMC?
lower 2/3rds of the esophagus is made of ____ muscle.
plexus primarily controls secretion and blood flow. It also receives sensory information from chemo and mechano receptors
Important for keeping the GI tract clear of harmful bacteria or residual foodstuffs in the absence of food
contraction of this layer of smooth muscle causes a shortening of a segment of the GI tract
t/F: Sensory input from the internal anal sphincter occurs via the pelvic splanchnic nerves.
controls external anal sphincter
T/F:At least 50% of stomach contents are released in 24-48 hours.
T/F: The hypogastric nerve provides inhibitory input (via a adrenergic) to circular smooth muscle layer and stimulatory input to the longitudinal layer of the GI
name the 2 ganglia that are responsible for sympathetic control of the upper GI

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