Science Quiz / Gastric Physiology

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Can you name the Gastric Physiology?

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QuestionAnswer
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
these cells produce pepsinogen and gastric lipase
How does potassium get out of the parietal cell?
Secretin ____ (promotes or inhibits) gastric emptying
what activates pepsinogen?
2 causes of peptic ulcers
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
The gland of the stomach is known an ____ gland.
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
2nd messenger involved in activation of the parietal cell
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
responsible for getting H+ ions into the lumen of the stomach
T/F: Rate of gastric emptying increases with rectal and colonic distention.
T/F: Ghelin is released during fasting which stimulates appetite
T/F: Ileal fat increase gastric emptying.
this hormone acts at the hypothalamus to suppress appetite
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
CCK ____ (promotes or inhibits) gastric emptying
which two products of oxidative phosphorylation are important for the production of stomach acid.
P/D1 cells are located where?
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
these cells produce histamine
Which histamine receptor is found on the basolateral membrane of the parietal cell?
Cl ions are transported into the lumen of the stomach using which type of transport protein?
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
these cells produce somatostatin
QuestionAnswer
P/D1 cells release what hormone?
leptin is release by which type of tissue?
T/F: An increase in pH (basicity) slows gastric emptying.
T/F: Large volumes in the stomach increase gastric emptying
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
enzyme important for the production of protons and bicarbonate in the parietal cell
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
prilosec or omeprazole acts by inhibiting what?
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
T/F: The stomach is the major site for digestion.
these cells produce HCl and intrinsic factor
H2 blockers prevent the binding of ____ to prevent the production of acid.
T/F: ECL cells can be activated by acetylcholine or gastrin
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
made by the I cells of the duodenum
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
essential for binding and absorption of vitamin B12
these cells produce gastrin
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
Cl ions are transported into the parietal cell using which type of transport protein?
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
Hypoglycemia ___ (increase or decreases) gastric emptying.
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
severely delayed gastric emptying or no emptying
made by the S cells of the duodenum
This type of drug inhibits prostaglandin related defense mechanisms within the stomach

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