Science Quiz / Cell Signaling

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Can you name the the HYTQ concepts?

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QuestionAnswer
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
these enzymes remove phosphate groups added by kinases
true or false: intracellular receptors regulate transcription.
G proteins are active when what molecule is bound?
release mechanism for thyroid hormones
which subunit of the G-protein binds GTP and GDP?
cAMP is synthesized by what?
term for signal that stably occupies a receptor
CRE stands for what?
steroid hormones bind which type of receptor? (cell surface or intracellular)
cAMP binds the ______ subunit of protein kinase A (PKA)
these receptors bind to signaling molecules that diffuse into the cell
term for molecules that mimics signal of ligand (e.g., drug)
this type of receptor protein is a channel for ion transport
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
PKA catalytic subunits phosphorylate what?
thyroid hormones bind which type of receptor? (cell surface or intracellular)
QuestionAnswer
release mechanism for steroid hormones
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
this protein activates G proteins by exchanging GDP for GTP
this protein inactivates G protein
hydrophilic molecules generally bind to _____ receptors.
Phosphotyrosines recruit which adaptor protein
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
hydrophobic molecules generally bind to _____ receptors.
Active RTK phosphorylates ______ residues
enzyme that phosphorylates protein target
these receptors bind to signaling molecules that do not diffuse into cell
release mechanism for catecholamine hormones
release mechanism for protein or peptide hormones

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