Science Quiz / Cell Signaling

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Can you name the the HYTQ concepts?

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QuestionAnswer
this protein activates G proteins by exchanging GDP for GTP
Active RTK phosphorylates ______ residues
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
G proteins are active when what molecule is bound?
enzyme that phosphorylates protein target
release mechanism for protein or peptide hormones
this protein inactivates G protein
these enzymes remove phosphate groups added by kinases
which subunit of the G-protein binds GTP and GDP?
release mechanism for steroid hormones
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
PKA catalytic subunits phosphorylate what?
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
term for signal that stably occupies a receptor
these receptors bind to signaling molecules that diffuse into the cell
term for molecules that mimics signal of ligand (e.g., drug)
QuestionAnswer
cAMP is synthesized by what?
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
these receptors bind to signaling molecules that do not diffuse into cell
hydrophilic molecules generally bind to _____ receptors.
Phosphotyrosines recruit which adaptor protein
cAMP binds the ______ subunit of protein kinase A (PKA)
CRE stands for what?
release mechanism for thyroid hormones
thyroid hormones bind which type of receptor? (cell surface or intracellular)
this type of receptor protein is a channel for ion transport
true or false: intracellular receptors regulate transcription.
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
steroid hormones bind which type of receptor? (cell surface or intracellular)
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
hydrophobic molecules generally bind to _____ receptors.
release mechanism for catecholamine hormones

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