Science Quiz / Pediatrics COMAT

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Can you name the Pediatrics COMAT?

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_________ is the most common cyanotic heart disease of childhood.
_____: Examination reveals a continuous 'machinery murmur' at the second left intercostal space at the sternal border, a loud S2, wide pulse pressure, and bounding peripheral pulse
_____ syndrome: A deficiency of alpha-L-iduronidase. Leads to corneal clouding, mental retardation, and gargoylism.
Age ____: 8 words
Age ____: Walks alone. Uses 1-3 words
The most common cause of bowl obstruction in the first 2 years of life. Usually seen between 3 months and 3 years of age. Abdominal pain, vomiting, and bloody mucus in stool 'curra
_____ isolated on a vaginal culture is definitive evidence of sexual abuse.
_____ disease: An absence of hexosaminidase that leads to GM2 ganglioside accumulation. Presents with cherry-red spot but no hepatosplenomegaly
______ is the most common congenital heart condition presenting with cyanosis within the first 24 hours of birth.
Name a cyanotic heart defect
Coarctation of the aorta is associated with ______ syndrome.
Age ____: Hops, copies a cross. Exhibits cooperative play
In most cases of intussusception, an air contrast ____ enema is both diagnostic and therapeutic.
_____ syndrome: A deficiency of iduronate sulfatase. A mild form of Hurler's syndrome with no corneal clouding and mild mental retardation. X-linked recessive.
Name a noncyanotic heart defect
Pneumatosis intestinalis on plain films is pathognomonic for _______ in neonates.
_______ conditions' 'blue babies' - have right to left shunts in which deoxygenated blood is shunted into the systemic circulation
Age ____: Skips, walks backward for long distances, copies a triangle, uses 5-word sentences
Age ____: 1 word, 1 step command
_____ syndrome: Presents with severe mental retardation, rocker-bottom feet, low-set ears, micrognathia, clenched hands, and a prominent occiput. Trisomy 18
______: Drug used to close a Patent Ductus Arteriosus
_____ syndrome: 47, XXY- Presents with testicular atrophy, tall stature, long extremities, gynecomastia, and female hair distribution.
_____ disease: Caused by a deficiency of glucocerebrosidase. Cells have a characteristic 'crinkled paper' appearance.
_____: Most common cause of congenital heart disease.
Age ____: 2-word phrases, 2-step commands
_____ disease: A deficiency of sphingomyelinase. May present with cherry red spot and hepatosplenomegaly.
_____: has a fixed, widely split S2
Age ____: Lifts head or chest when prone
Infants with FTT will fall first off the weight curve, then the height curve, and finally the _____ curve
_____ syndrome: CATCH22- Cardiac abnormalities, abnormal facies, thymic aplasia, cleft palate, hypocalcemia, 22q11 deletion
Age ____: Crawls, pulls to stand
Age ____: Walks up and down steps, 2-word phrases
______ syndrome: 45, XO- Features include short stature, shield chest, webbed neck, coarctation of the aorta.
The definitive diagnosis of Hirschsprung's disease requires a ______ biopsy.
Age ____: Rolls front to back, laughs and squeals
In ______ syndrome, left to right shunt leads to pulmonary hypertension and shunt reversal
Age ____: Rides tricycle. Copies a circle. Uses 3-word sentences.
Age ____: 5 words
_____ disease: Caused by a deficiency of alpha galactosidase. The first sign is severe neuropathic limb pain.
Age ____: Sits unassisted, babbles
_____ stenosis: Nonbilious emesis typically begins around 3 weeks of age and progresses to projectile emesis after most or all feedings. Examination may reveal a palpable olive-sha
_____ syndrome: Presents with severe mental retardation, microphthalmia, microcephaly, cleft lip, holoprosencephaly, polydactyly, and omphalocele.
Age ____: 3-word phrases
_____: A deficiency of arylsulfatase A that leads to accumulation of sulfatide in the brain, kidney, liver, and peripheral nerves.
The most common GI emergency in neonates. Most frequently seen in premature infants, but can occur in full-term infants as well.
Almost all cases of meconium ileus are due to _____
_____ disease: Absence of galactosylceramide and galactoside, leading to accumulation of galactocerebroside in the brain
Signs of _____ include no babbling or gesturing by 12 months, no single words by 16 months, no 2-word phrases by 24 months, failure to make eye contact, and other signs of deficits
_______ conditions - 'pink babies' - have left to right shunts in which oxygenated blood from the lungs is shunted back into the pulmonary circulation
Coarctation is a cause of secondary _______ in children.

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