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Diuretic Agents Quiz Stats

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x x % Correct
Reduces reabsorption of HCO3- in the kidney causing self limited diuresisAcetazolamide
83.6%
Inhibition of Na/K/Cl transporter in the ascending limb of Henle's loop Furosemide
83.6%
MOA: Inhibition of NaCl transporter in the distal convoluted tubuleHydrochlorothiazide
83.6%
Pharmacologic antagonist of aldosteroneSpironolactone
83.6%
Clinical applications: glaucoma, mountain sickness, edema with alkalosisAcetazolamide
81.8%
MOA: Physical osmotic effect on tissue water distribution because it is retained in the vascular compartmentMannitol
81.8%
MOA: Inhibition of the enzyme prevents dehydration of H2CO3 and hydration of CO2Acetazolamide
80%
Toxicities: Ototoxicity, hypovolemia, K wasting, hyperuricemia, hypomagnesemiaFurosemide
80%
Toxicity: Hyperkalemia, gynecomastiaSpironolactone
80%
Like spironolactone, more selective for aldosterone receptorEplerenone
80%
Mechanism like amiloride, much less potent, more toxic Triamterene
80%
MOA: Blocks epithelial sodium channels in collecting tubulesAmiloride
78.2%
x x % Correct
Used for peripheral edema, hypertension, acute hypercalcemia, hyperkalemia, acute renal failure, anion overdoseFurosemide
74.5%
Used for hypertension, mild heart failure, nephrolithiasis, nephrogenic diabetes insipidus Hydrochlorothiazide
70.9%
Toxicities: Hypokalemic metabolic alkalosis, hyperuricemia, hyperglycemia, hyponatremiaHydrochlorothiazide
69.1%
Sulfonamide similar to thiazide Indapamide
67.3%
Not a sulfonamide but has typical loop activity and some uricosuric action loop diureticEthacrynic acid
65.5%
Toxicity: Hyperkalemic metabolic acidosis Amiloride
65.5%
Only parenteral thiazide availableChlorothiazide
60%
Toxicities: metabolic acidosis, renal stones, hyperammonemia in cirrhotics Acetazolamide
58.2%
Toxicity: Nausea, vomiting, headache. May enhance congestive heart failure or cause pulmonary edema.Mannitol
58.2%
Antagonist at V1a and V2 ADH receptors. Reduces water reabsorption and increases plasma Na concentrationConivaptan
52.7%
Popular for use with loop agents for synergistic effectsMetolazone
49.1%
Toxicity: Infusion site reactions Conivaptan
49.1%

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Created Feb 12, 2011ReportNominate
Tags:agent, diuretic

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