Science Quiz / Alcohol = Kosher Wine in Shabbat

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Can you name the Alcohol yay! ?

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Alcohol, phenytoin and aspirin follow _____-order kinetics
_______ causes nausea, facial flushing, dizziness, and headache during alcohol metabolism.
Alcohol is similar to water, thus distributes to all _______ spaces.
Two major neuronal targets of ethanol are increased GABA activity and decreased _______ receptor activity.
_____ receptor is the most extensively researched but may not be the most important ethanol site.
Acute ethanol effect on smooth muscle is vaso_____, smooth muscle relaxation, hypothermia in cold environements.
_____ dependence - need for continued drug exposure to avoid withdrawal symptoms. hyperexcitability, convulsions, toxic psychosis, and delirium tremens (severe cases), symptoms of catecholamine excess
A reduced effect upon repeated exposure to a constant drug dose, or the need for an increased dose to maintain an effect
The compulsive desire to use a drug despite adverse consequences; this craving can exist without drug tolerance or dependenceNucleus Accumbens
There is a __% increased risk of alcoholism if there is a family history.
Type I alcoholic involves the ______ pathway. Less severe, found in both males and females.
Type 2 alcoholic inoves the _______ pathway. It is males only, early onset, and more heritable.
Chronic tolerance of alcohol involves decreased _____ binding and affinity. Cross tolerance.
CAGE- C= cut down, A= annoyed, G= Guilty, E= ______
Long term ethanol exposure increase the number and _____ of enzymes that metabolize ethanol. Long-lasting changes in the abundance and function of those targets affected by acute ethanol exposure
________ Hypothesis: The brain then responds to this disruption by inducing an opposing chemical adaptation that tends to restore the neurochemical balance.
Chronic tolerance of alcohol results in decreased Calcium uptake and increased dihydropyridine binding- channel antagonist that reduce ______ symptoms in animal models. Dihydropyridine = calcium channel blocker
Acute tolerance of alchol results in increased intracellular Calcium and ________ calcium influx. No effect on dihydropyridine binding.
Chronic alcohol tolerance ______ cAMPIncreased cAMP and decreased Ip3 and DAG in acute alcohol tolerance
Chronic alcohol abuse is the number 1 cause of _____ and the need for liver transplant.
Symptoms: opthalmoplegia, gait ataxia and confusion, memory loss. Cause: Vitamin B1 deficiency (thiamin)
Opioid receptor antagonist. Reduces subjective “high” associated with alcohol
Competitive inhibitor of NMDA receptors. Reduces craving in many addictive disorders. More effective when given in combination with naltrexoneSide effects GI distress and rash.
Toxicities of this drug includes visual disturbances, blurred vision, formaldehyde on breath or urine, bradycardia. It is metabolized by alcohol dehydrogenase to formaldehyde. Treat with Fomepizole
_____ neuropathy: The effect observed are weakness, gait ataxia, paresthesia, muscle cramps, numbness and burning dysethesia, which may be produced by nutritional deficiency and by
Heavy alcohol consumption for long durations results in ________ cardiomyopathy. Binge drinking or withdrawal result in ventricular arrythmias. Up-regulation of voltage-dependent Ca++ channels.
Chronic alcohol consumption results in increased risk of mouth, pharynx, larynx, esophagus, and _____ cancer.
Name a permanent effect of Fetal Alcohol Syndrome.
In Fetal Alchohol Syndrome, alcohol may increase neuronal _________.
Management of acute intoxication with alcohol involves rehydration with _____ solutions if the patient is vomiting.
Name a symptom of alcohol withdrawal.
________ are most commonly used to reduce alcohol withdrawal syndrome.
Inhibits Aldehyde dehydrogenase. Toxicities include inhibited metabolism of other drugs and hepatotoxitcity.
_______ poisoning: patient comes in with elevated anion and osmolar gap. Patient has severe acidosis and retinal damage. Absorbed through skin or intestinal tract
Ethylene glycol is converted by alcohol dehydrogenase into _______ acid crystals in renal tubules. Antifreeze, tastes sweet
Alcohol dehydrogenase inhibitor. Used for methanol or ethylene glycol toxicity. Common reactions are headache, nausea, dizziness, rash, metallic taste, abnormal smell

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Created Sep 10, 2011ReportFavoriteNominate
Tags:alcohol, wine, yay

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