Science Quiz / NSAIDs

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Can you name the NSAIDs?

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Has a half life of 1 hour. Toxicity includes allergic IgM related thrombocytopenic purpura
Slight COX I specificity. Toxicity includes Steven-Johnson epidermal necrolysis, thrombocytopenia, and agranulocytosis
Associated with interstitial nephritis.
Has a slight COX2 specificity. Toxicity similar to Ibuprofen
Used for cancer pain. Toxicity includes pseudoporphyria
Has a half life of 57 hours
Available IM and has high analgesic efficacy
Has a half life of 58 hours
Available OTC. Has a half life of 14 hours. Toxicities in rare cases include allergic pneumonitis and pseudoporphyria.
Has a half life of 26 hours. Toxicity includes pseudoporphyria.
GI bleeding is a common toxicity (20%). Has a slight COX 2 selectivity
Available in topical ointment
Less effective than aspirin. Non-acetylated
Popular for rheumatic conditions. Slight COX I specificity. Has more severe NSAID effects including CNS disturbances (hallucinations, confusion, depression)
Contraindicated in pregnancy
Available as ophthalmic drops
Available OTC and also inhibits lipoxygenase. Toxicity similar to Ibuprofen.

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