Science Quiz / USMLE Teratogens

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Can you name the Teratogens, according to First Aid?

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Effect on fetusTeratogen
Inhibition of intestinal folate absorption
Mental retardation, fetal alcohol syndrome
Preterm labor, placental problems, IUGR, ADHD
Placental abruption
Embryotoxic
Risk of spontaneous abortions
Kernicterus
Vaginal clear cell adenocarcinoma
Bone deformities, fetal hemorrhage, abortion
Caudal regression syndrome, transposition of great vessels
Neural tube defects
Recurrent infections, diarrhea
Congenital goiter or hypothyroidism
Triad: PDA (or PA hypoplasia), cataracts, deafness (+/- blueberry muffin rash)
CN VIII toxicity (ototoxicity)
Acute cholestatic hepatitis in mom
Hydrops fetalis
Ebstein's anomaly (atrialized right ventricle)
Effect on fetusTeratogen
Fetal hydantoin syndrome
Absence of digits, multiple anomalies
Mutagenesis
[multiple anomalies]
Notched teeth, saddle nose, short maxilla, saber shins
Cartilage damage
Granulomatosis infantiseptica
Teratogenic antifungal
Necrotizing encephalitis
'Gray baby'
Teratogenic antiviral
Limb defects ('flipper' limbs)
Encephalitis, vesicular lesions
Infx causing spontaneous abortion
Renal damage
Discolored teeth
Hearing loss, seizures
Triad: chorioretinitis, hydrocephalus, intracranial calcifications

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