Science Quiz / USMLE Teratogens

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Can you name the Teratogens, according to First Aid?

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Effect on fetusTeratogen
Mental retardation, fetal alcohol syndrome
'Gray baby'
Risk of spontaneous abortions
[multiple anomalies]
Vaginal clear cell adenocarcinoma
Discolored teeth
Encephalitis, vesicular lesions
CN VIII toxicity (ototoxicity)
Granulomatosis infantiseptica
Fetal hydantoin syndrome
Placental abruption
Absence of digits, multiple anomalies
Triad: chorioretinitis, hydrocephalus, intracranial calcifications
Bone deformities, fetal hemorrhage, abortion
Cartilage damage
Neural tube defects
Effect on fetusTeratogen
Recurrent infections, diarrhea
Renal damage
Hydrops fetalis
Caudal regression syndrome, transposition of great vessels
Preterm labor, placental problems, IUGR, ADHD
Ebstein's anomaly (atrialized right ventricle)
Limb defects ('flipper' limbs)
Acute cholestatic hepatitis in mom
Hearing loss, seizures
Infx causing spontaneous abortion
Teratogenic antiviral
Notched teeth, saddle nose, short maxilla, saber shins
Congenital goiter or hypothyroidism
Inhibition of intestinal folate absorption
Necrotizing encephalitis
Triad: PDA (or PA hypoplasia), cataracts, deafness (+/- blueberry muffin rash)
Teratogenic antifungal

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