Science Quiz / USMLE Teratogens

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Can you name the Teratogens, according to First Aid?

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Effect on fetusTeratogen
Notched teeth, saddle nose, short maxilla, saber shins
Renal damage
Cartilage damage
Hearing loss, seizures
Teratogenic antifungal
Encephalitis, vesicular lesions
Triad: PDA (or PA hypoplasia), cataracts, deafness (+/- blueberry muffin rash)
CN VIII toxicity (ototoxicity)
Infx causing spontaneous abortion
Absence of digits, multiple anomalies
Mutagenesis
Neural tube defects
[multiple anomalies]
Recurrent infections, diarrhea
Kernicterus
Vaginal clear cell adenocarcinoma
Discolored teeth
Hydrops fetalis
Effect on fetusTeratogen
Limb defects ('flipper' limbs)
Mental retardation, fetal alcohol syndrome
Fetal hydantoin syndrome
Granulomatosis infantiseptica
Acute cholestatic hepatitis in mom
Bone deformities, fetal hemorrhage, abortion
Caudal regression syndrome, transposition of great vessels
Congenital goiter or hypothyroidism
Triad: chorioretinitis, hydrocephalus, intracranial calcifications
Placental abruption
Teratogenic antiviral
Inhibition of intestinal folate absorption
Necrotizing encephalitis
Risk of spontaneous abortions
'Gray baby'
Embryotoxic
Ebstein's anomaly (atrialized right ventricle)
Preterm labor, placental problems, IUGR, ADHD

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