| Clue | Answer |
|---|
| This isoform of creatine kinase is found in smooth muscle and brain tissue and makes up only 1% of total CK. | |
| This enzyme combines ornithine and carbamoyl phosphate to make citrulline | |
| The methyl group needed for the conversion of dUMP to dTMP comes from... | |
| Since humans can't store purines we must get rid of them in this form | |
| CTP Synthase aminates UTP with an amino group from where? | |
| The glycine residue at the carboxyl end of ubiquitin attaches to what residue on the target protein? | |
| This enzyme is deficient in histidinemia | |
| This enzyme converts Argininosuccinate to Arginine and Fumarate. | |
| Enzyme that converts deoyuridine to dUMP | |
| What product builds up in ADA deficient SCID that inhibits deoxynucleotide synthesis | |
| Deficient enzyme in maple syrup urine disease | |
| Lacking OMP decarboxylase or orotate phosphoribosyltransferase causes this rare metabolic condition. Patients often have aneamia, leukopenia and retarded development. | |
| Cofactor of all aminotransferase reactions because amino group is first transferred to this molecule. | |
| Presence of creatine kinase in the blood can indicate ___________________. | |
| Aminotransferase put the amino group from alanine on alpha-ketoglutarate to form glutamate and ___________________. | |
| This amino acid is used in the production of melanin | |
| ________________ have a maple/cheesy smell. | |
| Ketogenic amino acids yield which compound(s)? | |
| PRPP synthase is negatively regulated by ________________ | |
| This transaminase enzyme helps the urea cycle by being involved in the recycling of fumarate to aspartate. | |
| Aspartate, Arginine, Leucine, Lysine and Phenylalanine are which type of N-Terminal amino acids? | |
| A deficiency of this enzyme would be indicated by Argininosuccinic Acidemia | |
| People with hyperammonemia are given ________________ so the body uses it for energy of protein | |
| If the CK found in the heart is greater than ______ U/L then an MI is probable. | |
| This enzyme catalyzes the formation of IMP and GMP from Hypoxanthine and Guanine and PRPP | |
| 20% of SCID cases are due to this enzyme deficiency | |
| A muscle cell that is fully charged with CP has a __________:1 ratio of CP:ATP | |
| CPS-II is most sensitive to PRPP during what cell phase? | |
| What immune cell carries out de novo synthesis of nucleotides? | |
| What amino acid is added to IMP to make AMP? | |
| This enzyme catalyzes the conversion of bicarbonate and ammonia (from glutamine) to carbomoyl phosphate, releasing glutamate. | |
| One type of this autosomal recessive disease stems from a deficiency of phenylalanine hydroxylase | |
| A genetic mutation in what enzyme can cause increased de novo synthesis of purines and hyperuricemia | |
| GMP, GDP, GTP, AMP, ADP and ATP all inhibit what enzyme? | |
| Deamination reactions create this highly toxic chemical that must be removed from the body. | |
| Pyrophosphates are the basis of this drug class which is used to treat osteoporosis. | |
| Branched chain ketoacid dehydrogenase requires what cofactor? | |
| This genetic disease is characterized by self-mutilating behavior | |
| Ribose-5-Phostphate is an intermediary in what pathway? | |
| Glycine, arginine and methionine are used to synthesize what? | |
| This molecule allosterically activates CPS-I | |
| What substrate is used to synthesize PRPP? | |
| This enzyme phosphorylates CPS-II to change its allosteric properties making it more easily activated | |
| In a healthy person ketovaline is broken down into ______________> | |
| CPS-II is most sensitive to UTP during the end of which cell phase? | |
| The commited step of de novo purine synthesis is conversion of PRPP to ____________________. | |
| This enzyme converts carbomoyl phosphate to carbomoyl aspartate | |
