Science Quiz / Biochemistry DNA/RNA Terms

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Can you name the Biochemistry DNA/RNA Terms?

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5' splice site sequence
Binds to 5' guanine cap and facilitates binding of 40s ribosomal subunit
-10 Promoter sequence (Pribnow box)
Site on tRNA that amino acid is added
Complex of one mRNA and many ribosomes translating it at one time
Promotes hydrolysis of peptide-tRNA bond at termination of prokaryotic translation
Antibiotic that inhibits peptidyl transferase and blocks aminoacyl-tRNA on 50s subunit
Topoisomerase II Inhibitor that prevents DNA from being resealed after it has been cut
Irinotecan is an inhibitor of this enzyme
Main enzyme that synthesize new DNA strands in eukaryotic DNA replication
3' Splice site sequence
Enzyme that synthesizes new DNA strands in mtDNA replication
DNA Polymerase that can maintain its function at high temperatures
Form of progeria with early onset and characterized by baldness, prominent scalp, eyes, forehead caused by mutation of LMNA gene
Etoposide is an inhibitor of this enzyme
-80 Promoter sequence
Enzyme that catalyzes the methylation of 5' cap on eukaryotic mRNA
-35 Promoter sequence
Antibiotic that inhibits fMet-tRNA from binding to P-site
Mutation characterized by a nucleotide change that changes an amino acid codon to a stop codon
'Housekeeping' sigma factor
Source of methyl group that is added to 5' cap
Initiator protein, binds to origin of replication in DNA replication
Enzyme that adds an amino acid to a tRNA (One enzyme per amino acid)
Enzyme that replaces RNA primer with 5'-3' exonuclease activity and 5'-3' polymerase activity
Prokaryotic RNA Polymerase subunit that binds to promoter (2 of them)
Topotecan is an inhibitor of this enzyme
Type of RNA polymerase that puts primer on template strand for DNA Replication
Disease of the skeleton in which the bone calcium slowly decreases making bones brittle
Area of mRNA that contains signal sequence for polyadenylation
snRNP that binds to the branch sequence
Antibiotic that inhibits translocation of prokaryotic ribosome by binding to 50s subunit
Enzymatic complex that splices introns from hnRNA
Signal sequence for adding Poly(A) tail
-25 Promoter sequence (Hogness box)
DNA mutation characterized by replacement of pyrimadine with a purine or purine with a pyrimadine
Antibiotic that blocks elongation of prokaryotic RNA leading to a number of short non-functional RNA being transcribed
snRNP that binds to the 5' splice site
Protein that separates RNA/DNA duplex and RNA polymerase at termination site
Prokaryotic RNA polymerase subunit that binds to template strand
Peptide that is a potent vasodilator
Primary enzyme responsible for adding nucleotides to the 3' end of the leading and lagging strands in prokaryotic DNA replication
Protein that binds to the TATA box in eukaryotic RNA transcription
Campotechin is an inhibitor of this enzyme
Prokaryotic RNA polymerase subunit that forms phosphodiester bonds during transcription
Sequence of proximal control element at -100 bp
Antibiotic that blocks the A-site on prokaryotic ribosome
Gene library prepared from mRNA in a tissue or cell
Disease characterized by inabilty of the body to remove UV-induced thymine dimers by nucleotide excision repair
Left handed DNA with 12 bp per 360 turn
Chemicals that structurally resemble purines and pyrimadines and may be incorporated into DNA in place of normal bases
Eukaryotic DNA polymerase responsible for DNA repair
Form of eukaryotic RNA Polymerase used to synthesize 28s, 18s and 5.8s rRNA
Starvation/Stationary sigma factor
Form of progeria with onset around puberty, characterized by looking much older than age, common elderly manifestations at early age, mutation of WRN gene
UVr protein that cuts makes cuts to the damaged strand in nucleotide excision repair
Eukaryotic DNA polymerase that acts with primase
Gene library prepared from total DNA in a cell or tissue
DNA sequence that repressor binds to preventing binding to enhancers and thus preventing up-regulation of gene expression
Antibiotic that blocks the beta subunit of RNA polymerase from forming phosphdiester bonds
RNA polymerase subunit responsible for recognizing specific promoter regionson DNA and unwinding DNA helix
The common sickle cell beta globin gene mutation is characterized by this type of mutation
Ribonucleoprotein that can add DNA sequence to linear chromosomes
They bind to ssDNA after it is unwound to keep the two strands apart
Form of alpha thalessemia characterized by loss of all four alpha chain genes
Tandem DNA sequence repeated in telomeres
Enzyme that adds guanosine triphosphate to the 5' end of mRNA
Form of eukaryotic RNA Polymerase used to synthesize 5s rRNA and tRNA
Toxin found in a mushroom that strongly inhibits RNA Polymerase II
Type of mutation caused by insertion or deletion of a nucleotide in DNA
Clinically harmless DNA variation that does not affect the phenotype
Mutation characterized by the replacement of a purine with a purine or pyrimadine with pyrimadine
Thymine analog that can cause an AT base pair to become a CG base pair after 2 rounds of replication
Common name for DNA blots
Hormone that stimulates osteoblasts to deposit calcium in bone, lowering blood calcium
Disease characterized by inability to grow/gain weight, impaired development of nervous system, photosensitivity and premature aging
Most mutagenic form of UV light
Mutation caused by UV light
Hormone that stimulates osteoclasts to break down bone, increasing blood calcium
Antibiotic that Binds to DNA template preventing from being used to make RNA
Common name for RNA blots
Enzymes that recognize specific DNA sequences and cleave both strands of DNA
DNA sequense Hae III recognized
DNA sequence reconized by EcoR1
Uneven end of DNA strands cut by restriction enzymes
Common name for protein blots
Maximum number of times a cell can divide before its telomeres become critically short
Inactive X chromosome in females that is in a highly condensed state
Process used to produce large amounts of DNA
Drug that is a thymine with the open OH group replaced by an N3 group. Used in treatment of HIV

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