Science Quiz / Biochemistry: Amino Acids and Proteins

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Can you name the Biochemistry: Amino Acids and Proteins?

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DefinitionTerms
Phenylalanine (Essential or Non-Essential)
Acidosis can be an indicator for.....
The most important buffer in maintaining pH balance in the blood
pKa=
The concept that upon each binding of an O2 to a heme subunit causes a higher affinity for the next O2 binding is called...
Protein folding is primarily driven by
Asparagine (Essential or Non-Essential)
Pressure at which 50% of hemoglobin is saturated
Adult Hb shifts the O2 binding curve to the...
The lid structure of the E. coli chaperonin system is
Threonine (Essential or Non-Essential)
Co-chaperone for Hsp70
Which hemoglobin state has a lower binding affinity for oxygen?
Drug that inhibits Hsp90 by binding to the ATP binding pocket
Less toxic Hsp90 inhibitor that blocks ATP binding pocket
The E. coli chaperonin system requires ________ ATP
A Hemaglobin structure
Sickle cell doesn't affect which Hb subunit chain?
Drug that induces erythropoesis of gamma-globin
Amino acid that forms covalent bonds between sulfers
When blood pH is above _________ it is considered alkalosis
Low temperature shifts the O2 binding curve....
This type of breathing can cause alkalosis.
Enzyme that assists in the formation, rearrangement and breaking of disulfide bonds
Heat shock protein family that is only involved in protein folding
Hypoventhilation makes the blood
Leucine (Essential or Non-Essential)
Histidine (Essential or Non-Essential)
Blood pH must be maintained around....
High temperature shifts the O2 binding curve...
Removing HCO3- ion (bicarbonate) from the blood by kidneys helps to ____________ pH.
DefinitionTerms
Fetal Hb shifts the O2 binding curve to the....
Normal range of female Hb at sea level
Alanine (Essential or Non-Essential)
Low pH causes the O2 binding curve to shift...
-log[H+]=
Blood pH above ________ can result in coma and death.
Deoxygenated Hb has a higher affinity for H+ ions
These help to stabilize the folding and unfolding intermediates
Similar proteins found in different organisms
Hsp90 works with which other protein?
Low 2,3-BPG levels shift the O2 binding curve
F Hemaglobin structure
Secondary structure is a result of __________________ between amino acids within a protein.
Methionine (Essential or Non-Essential)
When oxygen is bound to the heme iron it is in which form? (T or R)
Blood pH below _______ can result in coma and death.
________________ regions tend to be structural and functional regions between homologous proteins.
Functional regions of the tertiary structure are referred to as
Arginine (Essential or Non-Essential)
Proline (Essential or Non-Essential)
The higher the altitud you to the _________ Hb your body will produce? (more/less)
Aspartic Acid (Aspartate) (Essential or Non-Essential)
Tryptophan (Essential or Non-Essential)
Which secondary structure is more stable?
Cysteine (Essential or Non-Essential)
High pH causes the O2 binding curve to shift...
Failure of the lungs to eliminate CO2 as fast as it is produced is called
Serine (Essential or Non-Essential)
When oxygen is not bound to the heme iron it is in which form? (T or R)
P50 of adult Hb (mmHg)
Hb with ferric form of iron ion can't beind oxygen. This form of Hb is called....
DefinitionTerms
A2 Hemoglobin structure
Persistent, prolonged vomiting can result in...
The concept that deoxygenated Hb has a higher affinity for CO2
Alpha helicies are generally ______ resides long with _______ amino acids per turn
Co-chaperson for Hsp60
Isoleucine (Essential or Non-Essential)
Which organ plays the fastest role in maintaining blood pH?
Lysine (Essential or Non-Essential)
Low serum carbon monoxide concentration shifts the O2 binding curve
Normal range of male Hb at sea level
Heat shock protein family that is involved in protein folding, prevents aggregation and assists transport of proteins to organelles
Glycine (Essential or Non-Essential)
When the blood pH drops below ________ it is considered acidosis
P50 of fetal Hb (mmHg)
A1C Hemoglobin structure
At high pH the amino acid is ______________ at both the amino and carboxyl groups.
Removing CO2 from the blood by the lungs helps to ____________ pH
Hsp protein mutaions are known to be responsible for
High serum carbon monoxide concentration shifts O2 binding curve
Valine (Essential or Non-Essential)
At low pH the amino acid is ______________ at both the amino and carboxyl groups.
High 2,3-BPG levels shift the O2 binding curve....
Hsp70 mainly serves to
Glutamic Acid/Glutamate (Essential or Non-Essential)
 
Glutamine (Essential or Non-Essential)
Chemical that minimized the change in pH of a solution by binding excess H+ while also being able to release H+ if pH is low
When there are equal amounts of protonated and deprotonated acid molecules...
Chemical that 'locks' Hb in T-state forcing the release of oxygen

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