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Drugs Week 2
Can you name the Drugs Week 2?
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amshep
20m
28 Questions
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Which two drug classes inhibit 30S at 'A' site
The absorption of what two drug classes is impaired by di- and tri-valent cations?
Which two tetracyclines are eliminated renally?
Which two tetracyclines are eliminated hepatically?
Who should not take tetracyclines?
Do tetracyclines or tigecycline have stronger binding to 30s?
What drug class inhibits the 50s subunit at the 'P' site?
Which macrolide must be coated to avoid destruction in the stomach?
What are the two mechanisms of resistance to macrolides?
Which macrolide inhibits P450?
Which macrolide can induce clindamycin resistance?
What drug class mimics PABA?
What enzyme is competitively inhibited by sulfonamides?
What drug inhibits DHFR?
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The interaction between sulfonamides and trimethoprim can be described as?
Sulfonamides and trimethoprim inhibit what enzyme complex, leading to drug interactions?
Which enzyme is the primary target of fluoroquinolones in G- bacteria?
Which enzyme is the primary target of fluoroquinolones in G+ bacteria?
Are active drug efflux and alteration of the two enzyme targets of fluoroquinolones encoded on plasmids or chromosomes?
Which drug class may cause tendonitis/tendon rupture?
What drug does not reach antibacterial concentrations in plasma due to its short half life?
What type of infection is the above drug used to treat?
People who have this deficiency should not take sulfonamides or nitrofurantoin.
What drug blocks the formation of the initiation complex by binding to the 50s subunit?
Mutations in which ribosomal subunit's RNA can prevent binding of the above drug?
What enzyme mediates methylation of the above subunit to also block drug binding?
Long term use of linezolid can lead to what?
The inhibition of monoamine oxidase by linezolid can lead to toxicity of what substance?
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