Science Quiz / Steroid Synthesis Pathway

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Can you name the substrates and enzymes involved in steroid synthesis?

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HintAnswerExtra
Substrate
Enzyme
Substrate
Enzyme Across the mineralocorticoid pathway!
Substrate
Enzyme
Substrate
Enzyme
Substrate
Enzyme
Substrate
Enzyme
SubstrateThat's it for the mineralocorticoid pathway!
Now where were we? (substrate)Before we branched off!
EnzymeNow go down towards the glucocorticoid pathway.
Substrate
EnzymeAcross the glucocorticoid pathway!
Substrate
Enzyme
Substrate
Enzyme
SubstrateThat's it for the glucocorticoid pathway!
Okay, now where were we? (substrate)Before we branched off!
HintAnswerExtra
Enzyme Let's make some androgens (go down).
Substrate
EnzymeWhat if the substrate was sulfated?
Substrate
OK lit, now where were we? (substrate)Before we did some sulfating.
EnzymeLet's make some estrone (go across).
Substrate
Enzyme
SubstrateYay!
Now where were we? (substrate)
EnzymeLet's make some estradiol this time (go down).
Substrate
Enzyme
Substrate
Enzyme
SubstrateYay! That covers all the horizontal pathways...
Now let's do vertical :) Say OK
What makes progesterone into 17 hydroxyprogesterone?
What makes that into D4 androstenedione?
What makes that into testosterone?
What makes that into dihydrotestosterone?
What makes estrone into estradiol?Congrats, you survived!

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Created Feb 19, 2020ReportNominate
Tags:Extra, Pathway, Steroid

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