Science Quiz / USMLE First Aid Rapid Review - Classic Labs / Findings

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Can you name the USMLE First Aid Rapid Review - Classic Labs / Findings?

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Clinical presentationDiagnosis / diseasecharacteristic features
Mammary gland (blue-domed) cyst
“Brown” tumor of bone
Rectangular, crystal-like, cytoplasmic inclusions in Leydig cells
Antidesmoglein (epithelial) antibodies
Cardiomegaly with apical atrophy
“Tennis-racket” shaped cytoplasmic organelles (EM) in Langerhans cells
Bamboo spine on X-ray
Dysplastic squamous cervical cells with enlargement and hyperchromasia
WBCs that look “smudged”
“Thumb sign” on lateral x-ray
Monoclonal globulin protein in blood / urine (κ or λ Ig chains)
Monoclonal antibody spike (AL)
Bloody tap on LP
Pseudopalisading tumor cells on brain biopsy
Eosinophilic globule in liver
Monoclonal globulin protein in blood / urine (IgM)
Basophilic stipping of RBCs
Depigmentation of neurons in substantia nigra
Rhomboid crystals, positive birefringent
Anti-topoisomerase antibodies
Hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)
Circular grouping of dark tumor cells surrounding pale neurofibrils
Enlarged cells with intranuclear inclusion bodies
Extracellular amyloid deposition in gray matter of brain
RBC casts in urine
Protein aggregates in neurons from hyperphosphorylation of protein tau
“Onion-skin” periosteal reaction
Elevated hCG
Periosteum raised from bone, creating triangular area
Honeycomb lung on x-ray
Silver-staining spherical aggregation of tau proteins in neurons
Thyroid-like appearance of kidney
Increased uric acid levels (arthritis)
Desquamated epithelium casts in sputum
Clinical presentationDiagnosis / diseasecharacteristic features
Antihistone antibodies
Sheets of medium-sized lymphoid cells (“starry sky” appearance on histology)
Basophilci nuclear remnants in RBCs
Hypochromic, microcytic anemia (abnormal hemoglobin)
Anti-IgG antibodies
Anti-transglutimnase / antigliadin / anti-endomysial antibodies
Thrombi made of white / red layers
High level of D-dimers
Enlarged thyroid cells with ground-glass nuclei
Renal epithelial casts in urine
Heterophile antibodies
Anticentromere antibodies
Podocyte fusion on EM
Bronchogenic apical lung tumor
Iron-containing nodules in alveolar septum
“Soap bubble” in femur or tibia on x-ray
Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells
Nodular hyaline deposits in glomeruli
Eosinophilic cytoplasmic inclusion in nerve cell
Increased α-fetoprotein in amniotic fluid / maternal serum
Monoclonal antibody spike (M protein = usually IgG or IgA)
“Nutmeg” appearance of liver
Narrowing of bowel lumen on barium radiograph
Monoclonal antibody spike (M proteins = IgM)
Colonies of mucoid Pseudomonas in lungs
Monoclonal antibody spike (normal consequences of aging)
Antinuclear antibodies (ANAs: anti-Smith and anti-dsDNA)
Hypochromic, microcytic anemia (bleeding)
“Hair-on-end” (crew cut) appearance on x-ray
Cellular crescents in Bowman’s capsule
Disarrayed granulosa cells in eosinophilic fluid
Azurophilic granular needles in leukemic blasts
Mucin-filled cell with peripheral nucleus
“spikes” on basement membrane, “dome-like” endothelial deposits
Clinical presentationDiagnosis / diseasecharacteristic features
Antiplatelet antibodies
Rib notching
Giant B cells with bilobed nuclei with prominent inclusions (“owl’s eyes”)
Hypochromic, microcytic anemia (stippling)
Large lysosomal vesicles in phagocytes, immunodeficiency
Increased uric acid levels (HGPRT deficiency)
Glomerulus-like structure surrounding vessel in germ cells
Yellow CSF
Low serum ceruloplasmin
“Chocolate cyst” of ovary
Increased uric acid levels (lymphomas)
Lytic (hole-punched) bone lesions on x-ray
Increased uric acid levels (hypertension)
Lumpy-bumpy appearance of glomeruli on immunofluorescence
Triglyceride accumulation in liver cell vacuoles
Stacks of red blood cells
Degeneration of dorsal column nerves
Branching gram-positive rods with sulfur granules
Hypersegmented neutrophils
“boot shaped heart on X-ray
Anti-neutrophil cytoplasmic antibodies
“wire-loop” glomerular appearance on LM
Polished, “ivory-like appearance of bone at cartilage erosion
Needle-shaped, negatively birefringent crystals
“Tram-track” appearance on LM
Heart nodules (inflammatory)
Stippled vaginal epithelial cells
Eosinophilic cytoplasmic inclusion in liver cell
Anti-mitochondrial antibodies
Anti-glomerular basement membrane antibodies
Intranuclear eosinophilic droplet-like bodies
Hexagonal, double-pointed, needle-like crystals in bronchial secretions

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