Science Quiz / Infectious diarrhea

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Can you name the Infectious diarrhea?

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CharacteristicsInfectious OrganismEpidemiology
Facultative anaerobe; invades enteric mucosa forming microabscesses due to toxinFound in crowded conditions and the homosexual population
Associated with IgA deficiency; causes malabsorption and secretory diarrheaObtained by drinking from freshwater contaminated by animal feces
Toxin and co-regulated pilus cause severe secretory diarrhea which can cause bicarb and potassium lossCommonly found with flooding or eating contaminated shellfish
2-3 day incubation; presents with severe pneumonia; 90% mortality rateAnimal reservoir = rat and squirrel; transmitted by respiratory droplets
Shiga-like toxin destroys intestinal villi; can cause acute renal failure, hemolytic anemia and thrombocytopeniaFecal-oral transmission in contaminated food
ATR gene promotes resistance to gastric acidFound in eggs and dairy
Gram negative rod; microaerophile with polar flagellumFound in contaminated poultry (not in food handlers)
Direct bacterial destruction of small intestinal brush border leading to malabsorptionSeen in infants in developing countries
Gram positive rod; causes large joint arthralgia and hyperpigmentation of skinSeen in male farmers and T-cell immune deficiency
Surface LPS causes damage to intestinal mucosa form microabscesses and crypt abscessesFound in contaminated poultry
CharacteristicsInfectious OrganismEpidemiology
1-6 day incubation; presents with grossly enlarged lymph nodes leading to sepsis and heart failureAnimal reservoir = rat and squirrel; higher incidence in veterinarians
1-2 week incubation; affects the terminal ileum; can lead to hepatitis, abscesses or osteomyelitisIncreased susceptibility in hemochromatosis patients
Bacterial agglutination which wedge in villi and crypts of Lieberkuhn, blocking absorption of fluid and increasing mucus secretionSeen in infants in developing countries
Facultative anaerobe; adheres to M cells in Peyer's patchesFound in poultry
Pseudomembranous colitis due to A and B toxinsNosocomial infection
Epithelial destruction and inflammation due to colonic invasionFecal-oral transmission often seen in travelers
10-14 day incubation; engulfed in macrophages and then spreads via lymphaticsTransmitted by food handlers
Gram negative curved rod; facultative anaerobe; halophileFound in alkaline environments
LT-1 and STa toxins enter mucosa causing secretory diarrheaFecal-oral transmission often seen in travelers

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