The 'Platelet Phase' of hemostasis with platelet adhesion, aggregation, and formation of platelet plug.
The 'Fluid Phase' of hemostasis involved in Coagulation Cascade and formation of the Fibrin Clot.
TF & FVII are part of the Extrinsic or Intrinsic pathway?
FXII, FXI, FIX, FVIII are part of the Extrinsic or Intrinsic pathway
The 'thrombin burst' is the end result of what?
What clotting factor stabilizes the fibrin clot via covalent bonds?
What is most important to obtain in Diagnosis of a Bleeding Disorder?
These symptoms indicate a problem with Primary Hemostasis:
These symptoms indicate a problem with Secondary Hemostasis:
What test is the 'gold standard' for assessment of platelet function?
What clotting factor is associated with vWF?
What test measures the Extrinsic pathway clotting factors function?
What test measure the Intrinsic pathway clotting factors function?
In a 'mixing study' when recombinant clotting factor is added to the patient's plasma what occurs to the clotting time when an 'inhibitor' is present?
In a 'mixing study' when recombinant clotting factor is added to the patient's plasma, what occurs to the clotting time when the 'factor is deficient'?
What disease has an 'acquired anti-phospholipid antibody' that results in a 'transient, benign condition' in young children.
This *PFA-100 *CT measurement indicates presence of Aspirin: (*Platelet Function Analyzer-100....*Closure Time)
This *PFA-100 *CT measurement indicates vWD or platelet disorders: (*Platelet Function Analyzer-100....*Closure Time)
*PFA-100 is good for 'screening' of platelet disorders because of its: (*Platelet Function Analyzer-100)
FVIII assay, vWF-Ag assay, and vWF activity assay are part of what panel?
Ristocetin added to normal plasma that has vWF will result in:
Ristocetin added to vWF-deficient plasma will result in:
What is a likely cofactor deficiency of newborns born at home and not at a hospital?
What are the Vitamin K-dependent clotting factors? (FII=Prothrombin)
In 'Mild' Vitamin K deficiency, what causes the pronounced prolonged PT? (Hint= 1 of the Vit K-dependent clotting factors)
What test screens for a FXIII deficiency? (Near immediate Lysis of Clot occurs if test positive)
What happens to the Fibrin clot in FXIII deficiency?
Prolonged aPTT & PT and clinical bleeding may occur when 'any plasma coagulation factor is less than':
The standardized measurement of PT used specifically for Warfarin therapy is: (used to standardize for different type of thromboplastin (TF) used in PT assays)
Hemophilia A is due to what?
Hemophilia B is due to what?
Heparin contamination, Lupus anticoagulant, Hemophilia A/B, vWD, or Contact Factor deficiency would yield Isolated Prolonged aPTT or PT?
Congenital FVII deficiency, Mild Liver disease, Mild Vit K deficiency would yield Isolated Prolonged aPTT or PT?
*DIC, Vit K deficiency, Liver disease, & Rare Congenital Factor Deficiencies would yield an Isolated Prolonged aPTT or PT? (*Disseminated Intravascular Coagulation- Consumption of multiple clotting factors)
What deficiency would result in 'Normal PT & aPTT'?
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