Science Quiz / Antiparkinson Drugs

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Can you name the Antiparkinson Drugs?

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HintDrug1st or 2nd Line
Dopamine replacement therapy; commonly administered orally; must be administered with carbidopa to block metabolism in the periphery; serious motor side effects after long-term useFirst Line
D2-like receptor agonist; increasingly used as initial treatment; may cause orthostatic hypotensionFirst Line
Some efficacy with respect to tremor, but relatively ineffective for the more disabling features of PD; cognitive side effects and troublesome central and peripheral cholinergic siSecond Line
Inhibits extracellular dopamine degradationSecond Line
Inhibits dopamine degradation; neuroprotective in lab models, but not established; only modest antiparkinsonian effectSecond Line
Mechanism not clear; mild therapeutic effects; used for mild PD symptomsSecond Line

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