Science Quiz / Multiple sclerosis

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Can you name the Multiple sclerosis?

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daclizumab stimulates what kind of cell
alemtuzumab targets this cell marker
this novel oral agent causes an immune response from th1 to th2
this drug inhibits dihydroorotate dehydrogenase,
classify ms: attacks occur, baseline disability slowly rises
s1p1 receptor modulator
the other use for rituximab
what is the cell marker on nk cells
classify ms: attacks occur, baseline disability remains stable
classify ms: attacks come and go, suddenly baseline disability sharply increases
cd 52 is highly expressed on what type of cell?
trade name: interferon that can be given once weekly
teriflunomide inhibits t cells by blocking their interaction with what?
what ion channel does fampridine block?
approved for use in rrms, spms, side effects: infection, cardiomyopathy, leukemia, leukopenia
this monoclonal antibody targets cd 20+ cells
this monoclonal antibody blocks leukocyte trafficking across the bbb
classify ms: no attacks, immediate increase in baseline disability
dihydroorotate dehydrogenase is involved in synthesis of what building block?
this achE inhibitor helps cognition
xxx
these drugs are used for depression
cladribine causes reductions in cells positive for what marker
natalizumab is an antibody against what cytokine?
this is the major side effect of mitoxantrone
trade name: glatiramer acetate
this study monitors the side effects of mitoxantrone and should be performed often
mab against cd 25
what symptom can be improved with use of fampridine
route of administration of most interferon drugs
this drug blocks potassium channels and helps with gait
how often should copaxone be given?
these drugs can be used for fatigue
this drug uses an active metabolite to decrease oxidation, protecting axons from inflammatory mediators
this drug inhibits dna synthesis by generation of 2-chlorodeoxyadenosine triphosphate
trade name: interferon beta1b
acute exacerbations are treated by?
use these drugs for muscle spasticity
this drug prevents the formation of eae, reducing the lymphocyte egress from lymph tissue
interferons and glatiramer primarily work by decreasing the number of what kind of cell?

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