Science Quiz / Multiple sclerosis

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Can you name the Multiple sclerosis?

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this monoclonal antibody targets cd 20+ cells
classify ms: attacks occur, baseline disability remains stable
the other use for rituximab
this drug uses an active metabolite to decrease oxidation, protecting axons from inflammatory mediators
this drug prevents the formation of eae, reducing the lymphocyte egress from lymph tissue
this drug blocks potassium channels and helps with gait
this drug inhibits dna synthesis by generation of 2-chlorodeoxyadenosine triphosphate
acute exacerbations are treated by?
classify ms: attacks come and go, suddenly baseline disability sharply increases
these drugs can be used for fatigue
this is the major side effect of mitoxantrone
mab against cd 25
s1p1 receptor modulator
trade name: interferon beta1b
what ion channel does fampridine block?
approved for use in rrms, spms, side effects: infection, cardiomyopathy, leukemia, leukopenia
trade name: glatiramer acetate
classify ms: attacks occur, baseline disability slowly rises
cd 52 is highly expressed on what type of cell?
dihydroorotate dehydrogenase is involved in synthesis of what building block?
interferons and glatiramer primarily work by decreasing the number of what kind of cell?
teriflunomide inhibits t cells by blocking their interaction with what?
this study monitors the side effects of mitoxantrone and should be performed often
natalizumab is an antibody against what cytokine?
these drugs are used for depression
route of administration of most interferon drugs
classify ms: no attacks, immediate increase in baseline disability
this achE inhibitor helps cognition
this novel oral agent causes an immune response from th1 to th2
this drug inhibits dihydroorotate dehydrogenase,
alemtuzumab targets this cell marker
what is the cell marker on nk cells
trade name: interferon that can be given once weekly
use these drugs for muscle spasticity
how often should copaxone be given?
cladribine causes reductions in cells positive for what marker
what symptom can be improved with use of fampridine
this monoclonal antibody blocks leukocyte trafficking across the bbb
daclizumab stimulates what kind of cell

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