Miscellaneous Quiz / Bacterial Systemic Infections - NGR

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Can you name the Bacterial Systemic Infections - NGR?

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When injected by plague, these proteins can have a cytotoxic effect.
These three diseases can be transmitted by hard shell ticks
this family of ticks is the vector for lyme disease
Lyme disease, second stage: early dissemination can result in abnormalities of these two systems
late lyme disease is shown with fluctuating _________, including joint pain
This disease is caused by a facultative intracellular parasite, can affect the eyes, lungs, blood, and gi, caused by gram - rods
treatment: relapsing fever
wild rodents are responsible for this cycle of the plague
These are two virulence factors important for dissemination of the plague bacteria
contact dependent secretion, forms pore in eukaryotic cell membrane, injects toxic proteins directly into eukaryotic cells
most common form of tularemia 75% cases, low mortality
This pathogen is a spirochete
Pathogen: lyme disease
This is the leading vector borne disease in the US
a deer fly can transmit this disease
Diagnosis: Areas of multiplication are characterized by necrosis or granuloma production
treatment: 2 drugs for tularemia
Diagnose: in a gram stain, you find bipolar stained rods
this test is recommended for later stages of Lyme disease
Plague endotoxins can cause this kind of shock
major virulence factor of lyme disease, causes inflammation
higher incidence of Lyme disease occurs at the end of this season
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You would use microscopy during a febrile period to diagnose this borrelial infection
For RMSF, this is the most frequently used way of measuring rising antibody titer by the first week of illness
Pathogen: gram -, coccobacilli, obligate intracellular, thin murein layer
YOP
this type of plague is highly contagious
treatment: 2 drugs for plague
the diagnostic rash of lyme disease, bull's eye appearance, usually nontender and indicative of first stage infection
Def: piece of dead tissue that is about to slough off the surface of the skin
Diagnose: male died while carrying out an autopsy on a mountain lion, flu like symptoms first
septicemic plague is notably absent of
For RMSF, this process detects bacteria in the skin biopsy of the rash
Pathogen: plague
Diagnose: sudden onset, nonspecific flu like, later rash, petechial, hemorrhageic, first on extremities, spread centripetally to the entire body
Lesser virulence factor of lyme disease, causes autoimmune response and antigenic variation
infection caused by the transmission of microorganisms that naturally live in animals
cultures of this bacteria are highly infectious
A flea bite can cause transmission of this disease
For RMSF, this is the most rapid and specific diagnostic assay
Pathogen: gram -, rods, bipolar staining
treatment: 2 drugs for lyme disease
Injected YOPs suppress production of ______, interfering with immune system messaging
Pathogen: rocky mountain spotted fever
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this family of tick is the vector for rickettsii
During Direct immunofluorescence, F1 antigen is a sign of this virulence factor in plague
Pathogen: gram -, coccobacilli,
major virulence mechanism of relapsing fever
treatment: ricketts
Pathogen: tularemia
Diagnose: fever, rash, previous tick bite are important to diagnosing
Diagnose: this disease causes increased vasculitis, thrombosis, and vascular permeability
relapsing fever is due to this borrelia
Lyme disease: this is the first step of sensitive testing
In plague, this virulence factor prevents opsonization and phagocytic migration
Lyme disease: this second test is more specific
Diagnose: preferentially infect endothelial cells lining the small blood vessels
dark discoloration, black death describes this type of plague
Def: hemorrhagic suppurative lymphadenitis
Diagnose: man touched dead rabbits, fever, muscle aches, dry cough, small gram negative rods
Virulence factor: antiphagocytic part of plague
tularemia's anti phagocytic component
Diagnose: a facultative intracellular pathogen infects reticuloendothelial organs, multiplies in macrophages,
RMSF prefers to infect this type of cell

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