History Quiz / Myeloproliferative Disorders - Mahmoud

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Can you name the Myeloproliferative Disorders - Mahmoud ?

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This disorder is characterized by a genetic abnormality
This component of Virchow's Triad contributes to headache
When JAK2 is mutated, cells become abnormally sensitive to this glycoprotein hormone
This disorder can result in a ruddy complexion
in this myelogenous disorder, myeloid cells do not spill into the blood
Besides blast crisis, CML can also progress to this disorder, where bone marrow is replaced with scar tissue
PV involves excessive release of this cytokine
In late PV, the bone marrow can become ____________
A mutation in this tyrosine kinase can lead to PV
this is the most dominant cell line affected by PV
Excessive histamine release can result in this GI disease
This chromosome is present in 90% of patients with CML
Only blast cells are present in this myelogenous disorder
this acute condition occurs after the accelerated phase in CML patients
In regards to time, CML and PV are examples of this type of myeloproliferative disorder
in bone marrow, transformation into myelofibrosis marks the beginning of this phase
in the accelerated phase of cml, there is an increase in this type of immature cell
CML and MM share high levels of this purine byproduct
This is the principle site of extramedullary hematopoiesis
this type of cell is any leukocyte that is NOT a lymphocyte
This proper noun describes the three thrombolytic properties of PV
Look for decreased levels of this enzyme to differentiate cml from infection
Subcapsular infacts of the spleen are a characteristic finding of this disorder
extramedullary hematopoiesis in the liver is characteristic of which disease
the chronic phase of cml lasts for about this many years
High rate of cell turnover can produce excessive amounts of this byproduct
This is the formation of stacks of RBCs observed in peripheral blood
in this disorder, LAP levels are elevated
Hepatic vein thrombosis is associated with this myeloproliferative disorder`
In this stage of cml, one can find nodular tumors on the skin
These organs are most affected by PV
This type of PV is a stem cell disorder
High Hct/Hb, splenomegaly, and increased RBC mass are major diagnostic criteria of:
this clinical disorder describes an abnormally elevated hemoglobin or hematocrit
In MM, there is malignant proliferation of these platelet forming cells,
This is the most prominent picture of Myeloid metaplasia
For a CML CBC, you can expect markedly increased levels of this cell
In CML the transformed pluripotent stem cells predominantly differentiate into this type of cell

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