Science Quiz / Hermel Day 3

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Can you name the Hermel Day 3?

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This TNF antagonist is indicated in Crohn's disease, ulcerative colitis, and rheumatoid arthritis
Abatacept is fusion protein that interferes with this receptor
these drugs decrease the production of adhesion molecules
Methotrexate/rheumatrex is an antagonist of:
A homogenous antibody population that recognizes only one epitope
This receptor is the target of rituximab
A critical enzyme for the production of guanosine nucleotides required for DNA synthesis
Def: these are biologics containing a toxin or prodrug
denileukin delivers this toxin
Mylotarg/gemtuzumab ozogamicin results in this type of DNA damage
Tacrolimus: major side effect
Mylotarg/gemtuzumab ozogamicin targets cells bearing this receptor
Pancreatitis is a contraindication of this antiRA drug
This treatment down-modulates auto antibody productionused to treat lupus, xla, cvid
This fusion protein is used for RA, Crohn's disease, ulcerative colitis, psoriasis
calcineurin and mTOR inhibitors inhibit this immune cell activation
This treatment is effective in reducing the mortality of sepsis
These types of drugs are used for treatment of nearly all inflammatory conditions, especially on a short term basis
To reduce the emigration of leukocytes from vessels, you could decrease the number of _________ molecules
Acronym: CSF
denileukin only binds to cells that contain a ____ receptor
gemtuzumab delivers this toxin
First FDA approved immunoconjugate
Acronym mTOR
Etanercept binds to this factor
this drug targets active t cells only
the gold standard for treatment of rheumatoid arthritis
only fda mab used as an antibiotic
This protein phosphatase activates NFATc which upregulates IL2
first ORAL drug for Multiple Sclerosis
Recently fda approved, trafficking inhibitor, moa not fully understood, blocks lymphocytes from exiting lymph nodes
daclizumab targets the receptor of this interleukin
these chemical signals are used for restoration of hematopoiesis
cyclosporin, tacrolimus, and pimecrolimus are inhibitors of:
sirolimus aka rapamycin and rapamune, and everolimus are inhibitors of:
These drugs are antiinflammatory, but they are not immunosuppressive
these drugs inhibit transcription of inflammatory mediator genes
Toxicity highly associated with cyclosporine
drug: treat cancer AND immunosuppresant
etanercept and abatacept are examples of this type of protein
This drug inhibits T and B cell proliferation by blocking IMP-DH
T cells proliferate due to this interleukin
thrombocytopenia puts pts at increased risk of __________
drug: soluble IL1 receptor antagonist
neumega, leukine, and filgrastim are fda approved _____________ therapies
Reversible B lymphoproliferative disorders are a toxicity of this type of drug
Avoidance of patient immune response is a key requirement for the use of this type of drug
These agents have fewer side effects than any other immunosuppressive drugs
This drug is used in the treatment of atopic dermatitis
mycophenolate mofetil and azathioprine belong to this category of drugs

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Created Nov 13, 2010ReportNominate

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