Science Quiz / Hermel Day 3

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Can you name the Hermel Day 3?

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These types of drugs are used for treatment of nearly all inflammatory conditions, especially on a short term basis
Acronym: CSF
cyclosporin, tacrolimus, and pimecrolimus are inhibitors of:
Methotrexate/rheumatrex is an antagonist of:
A homogenous antibody population that recognizes only one epitope
denileukin delivers this toxin
Etanercept binds to this factor
Abatacept is fusion protein that interferes with this receptor
Recently fda approved, trafficking inhibitor, moa not fully understood, blocks lymphocytes from exiting lymph nodes
Tacrolimus: major side effect
Def: these are biologics containing a toxin or prodrug
calcineurin and mTOR inhibitors inhibit this immune cell activation
This fusion protein is used for RA, Crohn's disease, ulcerative colitis, psoriasis
these chemical signals are used for restoration of hematopoiesis
drug: treat cancer AND immunosuppresant
Acronym mTOR
This treatment is effective in reducing the mortality of sepsis
This receptor is the target of rituximab
This protein phosphatase activates NFATc which upregulates IL2
mycophenolate mofetil and azathioprine belong to this category of drugs
sirolimus aka rapamycin and rapamune, and everolimus are inhibitors of:
these drugs decrease the production of adhesion molecules
daclizumab targets the receptor of this interleukin
This treatment down-modulates auto antibody productionused to treat lupus, xla, cvid
Pancreatitis is a contraindication of this antiRA drug
these drugs inhibit transcription of inflammatory mediator genes
Mylotarg/gemtuzumab ozogamicin targets cells bearing this receptor
only fda mab used as an antibiotic
Mylotarg/gemtuzumab ozogamicin results in this type of DNA damage
T cells proliferate due to this interleukin
this drug targets active t cells only
First FDA approved immunoconjugate
This TNF antagonist is indicated in Crohn's disease, ulcerative colitis, and rheumatoid arthritis
gemtuzumab delivers this toxin
These drugs are antiinflammatory, but they are not immunosuppressive
etanercept and abatacept are examples of this type of protein
denileukin only binds to cells that contain a ____ receptor
To reduce the emigration of leukocytes from vessels, you could decrease the number of _________ molecules
neumega, leukine, and filgrastim are fda approved _____________ therapies
first ORAL drug for Multiple Sclerosis
Reversible B lymphoproliferative disorders are a toxicity of this type of drug
This drug inhibits T and B cell proliferation by blocking IMP-DH
This drug is used in the treatment of atopic dermatitis
These agents have fewer side effects than any other immunosuppressive drugs
the gold standard for treatment of rheumatoid arthritis
drug: soluble IL1 receptor antagonist
Avoidance of patient immune response is a key requirement for the use of this type of drug
Toxicity highly associated with cyclosporine
thrombocytopenia puts pts at increased risk of __________
A critical enzyme for the production of guanosine nucleotides required for DNA synthesis

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Created Nov 13, 2010ReportFavoriteNominate

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