Science Quiz / Hermel Day 2

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The treatment for pts with advanced disease for which alternative therapies are either nonexistent or have failed
This immunodeficiency affects both B and T cells
Characterized by complete lack of Ig, Bcells, germinal centers, tonsils, adenoids
A deficiency of these immune cells leads to difficulty with viruses
Patients who suffer from Wiskott Aldrich syndrome have defective organization of this cellular structure
Definition: A measure of relative specific antibody concentration in serum
Definition: movement disorders and abnormal superficial blood vessel development
To improve the survival of transplanted kidneys, one would be wise to match this MHC
SCID is an emergency this age group
This graft comes from fraternal twins and all other strangers
Symptom of IgA deficiency
This receptor is responsible for a failure of class switching
definition: pus forming
A graft puts a patient at high risk of infection from this opportunistic species
btk is necessary for this cell's development
This type of graft comes from twins and mice with identical MHC
Acronym: ALL
Receptor found on hematopoietic stem cells aka bone marrow producers
Serum levels from wiskott aldrich patients often show this trait
In DiGeorge syndrome, patients are missing this primary lymphoid organ
A four fold increase in titer is called:
This disease manifests as skin rash, diarrhea, jaundice, and bone marrow dysfunction
The treatment of choice for CVID is:
Most common B cell deficiency disease involves a lack of this immunoglobulin
Type of rejection that occurs within hours
This type of graft is more efficacious but there is a higher chance of relapse
Low height and weight, eczema, otitis media, and lack of response to Tindependent type 2 antigens are symptoms of this disease
In this disease, the donor cells attack the recipient
Acronym: HLA
TI-2 antigens involve this organic structure:
A deficiency of these immune cells leads to difficulty with encapsulated bacteria such as strep and Hib
An immunoglobulin that is a sign of an infection from the past
Acute infection involves high levels of this Ig
Type of rejection that occurs in days to weeks
In SCID, patients will have normal function of these immune cells
HIGM is characterized by an elevated level of this immunoglobulin
SCID due to defect in common cytokine gamma chain, IL4, 7, IFNgamma
XLA is due to a defect in this gene
major cause of graft failure
Most common type of SCID involves a deficiency of this:
The highest contraindication for transplantation
Type of rejection that occurs in 3-5 days
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Created Nov 11, 2010ReportNominate

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