Science Quiz / Hermel Day 1

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Can you name the Autoimmunity?

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These antibodies are very common in some autoimmune diseases
major genetic risk factor for several autoimmune diseasesmajor risk factor for several autoimmune disease
Type: delayed type hypersensitivity Tcell mediated
This is an important genetic diagnostic marker for SLE
mast cells affect the GI tract and peristalsis, causing.....
highly correlated with HLA DR3/DR4 genotype
systemic allergic reaction manifested by rapid and serious symptomslaryngeal obstruction, bronchospasm, asphyxiation, hypovolemic shock, urticaria, death
This hypersensitivity results in hard, raised swelling
penicillin allergies are triggered by this kind of reaction
These cytokines stimulate Th2 and B cell responses
all the DRB1*04 subtypes are associated with susceptibility to
Mantoux test, poison ivy reaction, and celiac disease are all examples of this type of reaction
What usually precedes and has high associations with autoimmunity?
location of pneumonitis
in DTH, T cells recruit these kinds of cells
disease: disruption of feedback regulation of thyroid hormone production
This antibody is the most common MEDIATOR of atopic dermatitis
Which autoimmune diseases CANNOT be treated with antibiotics?
Inflammation is due to this cytotoxin
Type: antibody mediated
This compound increases vascular permeability, contracts smooth muscle, increases vascular permeability, and is toxic to parasites
This hypersensitivity results in edematous swelling in the epidermis
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What is a soluble complex of antibody and antigen?
Definition: chemoattractants for granulocytes
what makes 0402 different
atopic individuals have a higher levels of.....
leukotrienes, cytokines, and inflammatory cells are involved in this phase
During an allergic reaction, recruitment of these cells causes inflammation and tissue damage
When self peptides mimic pathogen-derived peptides and stimulate T-cell responses
DRB1 subtype NOT associated with RA
These leukocyte chemotactic factors increase vascular permeability, mucus secretion
most common allergic disease in the US
Type: immediate hypersensitivity IgE mediated
this theory explains why Western lifestyles are more prone to allergy
mast cells in lungs ->bronchoconstriction -> ?
how to diagnose type 1 hypersensitivities
these cells are responsible for the classic wheal and flare reaction
90% of food allergies are caused by
The goal of desensitization involves building up these antibodies
gender most susceptible to autoimmune disease
histamine is responsible for this type of phase response
Type: immune complex method
eosinophils secrete these chemicals
disease caused by TH2 mediated inflammation of the lungs

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