Science Quiz / Hermel Day 1

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Can you name the Autoimmunity?

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The goal of desensitization involves building up these antibodies
Definition: chemoattractants for granulocytes
Which autoimmune diseases CANNOT be treated with antibiotics?
mast cells in lungs ->bronchoconstriction -> ?
What usually precedes and has high associations with autoimmunity?
these cells are responsible for the classic wheal and flare reaction
Type: immediate hypersensitivity IgE mediated
disease caused by TH2 mediated inflammation of the lungs
location of pneumonitis
This hypersensitivity results in edematous swelling in the epidermis
gender most susceptible to autoimmune disease
what makes 0402 different
major genetic risk factor for several autoimmune diseasesmajor risk factor for several autoimmune disease
Type: delayed type hypersensitivity Tcell mediated
most common allergic disease in the US
this theory explains why Western lifestyles are more prone to allergy
Mantoux test, poison ivy reaction, and celiac disease are all examples of this type of reaction
This is an important genetic diagnostic marker for SLE
This hypersensitivity results in hard, raised swelling
This antibody is the most common MEDIATOR of atopic dermatitis
mast cells affect the GI tract and peristalsis, causing.....
DRB1 subtype NOT associated with RA
90% of food allergies are caused by
This compound increases vascular permeability, contracts smooth muscle, increases vascular permeability, and is toxic to parasites
highly correlated with HLA DR3/DR4 genotype
eosinophils secrete these chemicals
all the DRB1*04 subtypes are associated with susceptibility to
penicillin allergies are triggered by this kind of reaction
disease: disruption of feedback regulation of thyroid hormone production
These leukocyte chemotactic factors increase vascular permeability, mucus secretion
how to diagnose type 1 hypersensitivities
During an allergic reaction, recruitment of these cells causes inflammation and tissue damage
Type: immune complex method
These antibodies are very common in some autoimmune diseases
histamine is responsible for this type of phase response
in DTH, T cells recruit these kinds of cells
systemic allergic reaction manifested by rapid and serious symptomslaryngeal obstruction, bronchospasm, asphyxiation, hypovolemic shock, urticaria, death
Inflammation is due to this cytotoxin
leukotrienes, cytokines, and inflammatory cells are involved in this phase
When self peptides mimic pathogen-derived peptides and stimulate T-cell responses
These cytokines stimulate Th2 and B cell responses
What is a soluble complex of antibody and antigen?
Type: antibody mediated
atopic individuals have a higher levels of.....

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