Science Quiz / AIDS Day

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This enzyme cleaves viral proteins for viral assembly
HIV can lead to a false negative when testing for this disease
mucosal ulcers and rash are part of the nonspecific symptoms of __________infection
Protease inhibitors have this suffix
Heterozygosity of this compound imparts protection to AIDS
PI: most potent inhibitor of cyp3a4
Coinfection with this virus promotes cytokines that resist AIDS
These cells initiate infection by transporting HIV from mucosal surfaces to lymphoid tissue
these 3 drugs should be taken on an empty stomach
Test: detect HIV specific proteins
AZT's highest toxicity
Known as azt, this is used in preventing vertical transmission of HIV
abacavir associated with this HLA
This protein product is bound to CD4 and CXCR4 chemokine receptors
these inhibitors prevent cleavage of gag pol polyprotein, resulting in immature noninfectious viral particles
emtricitabine's oral solution contains this and is thus contraindicated in pregnant women and children
During the early stage of HIV infection, this serum measurement is your most important predictor of progressive disease
env cleaves this to form gp120+gp41
Acronym: therapy for AIDS
abacavir can cause this type of reaction
adenosine analog with enteric coating, phenylalanine chewables, take on empty stomach
This gene makes the protein of the outer coating of the virus
The window period between infection and seroconversion is about ________ days
This fluorinated analog of lamivudine can be taken once daily
hepatic steatosis and lipid metabolism disorder is an adverse reaction of this class of drugs
This class of drugs does not need phosphorylation and does not compete with nucleoside triphosphate
This area has the most substantial loss of cd4 T cells
Test: viral load
Lamivudine should be coadministered with this combo drug
These patients have some degree of detectable viremia, but develop hiv about a decade later than normal
this NRTI should not be taken with tetracycline or fluoroquinolone
take this nnrti on an empty stomach, but watch out for CNS toxicity
This gene encodes the reverse transcriptase, integrase, and protease
Long term non progressors have strong production of __________
definition: AIDS wasting
This disease is the leading cause of infectious mortality in the world
Disfiguring major side effect of protease inhibitors
Activation of this immune cell initiates viral replication
delavirdine, efavirenz, and PI's are ______ of cyp enzymes
This PI is contraindicated with pts with hepatic failure and sulfa drug allergies
These HIV seropositive patients never progress to AIDS
fusion inhibitor of gp41
it is important to maintain hydration on an empty stomach with this protease inhibitor
when given with lopinavir, this drug acts as a pharmacologic enhancer
entry inhibitor, ccr5
this NRTI has dose dependent pancreatitis
toxoplasma, mycobacterium, pneumocystis, and herpes cause this type of infection for aids patients
Skin rash is a common result of these two nnrti
This protease inhibitor can cause hyperbilirubinemia with overt jaundice, increase in qt interval
zalcitabine should not be given with this NRTI
Test: detect antibodies to HIV
integrase inhibitor
lamivudine is a ______ analog
oral guanosine analog that can cross the bbb
The major receptor used by HIV to infect T cells
This NRTI is used to treat hep B and should be administered with TMP SMZ
fusion entry inhibitors act on these receptors
PI for pregnant women
this class affects p450 and limits its effectiveness and creation
This NRTI competes with Stavudine and can cause myelosuppression
NRTI: This analog of deoxythymidine can cause peripheral neuropathy
The first T cells to die are those that are specific for fighting _____infection
The C in ABC stands for
This NRTI should be avoided if the patient is taking didanosine
This type of HIV is found worldwide
hyperpigmentation of the palms is a side effect of this drug
An important prognosticator of late stage disease
This nnrti is a moderate inducer of cyp3a4
NRTI requires phosphorylation by _______ enzymes
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Created Nov 16, 2010ReportNominate

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