Science Quiz / AIDS Day

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Can you name the AIDS Day?

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Test: detect HIV specific proteins
it is important to maintain hydration on an empty stomach with this protease inhibitor
adenosine analog with enteric coating, phenylalanine chewables, take on empty stomach
HIV can lead to a false negative when testing for this disease
emtricitabine's oral solution contains this and is thus contraindicated in pregnant women and children
NRTI requires phosphorylation by _______ enzymes
The first T cells to die are those that are specific for fighting _____infection
delavirdine, efavirenz, and PI's are ______ of cyp enzymes
This NRTI is used to treat hep B and should be administered with TMP SMZ
when given with lopinavir, this drug acts as a pharmacologic enhancer
env cleaves this to form gp120+gp41
This gene encodes the reverse transcriptase, integrase, and protease
Coinfection with this virus promotes cytokines that resist AIDS
Activation of this immune cell initiates viral replication
This fluorinated analog of lamivudine can be taken once daily
These patients have some degree of detectable viremia, but develop hiv about a decade later than normal
NRTI: This analog of deoxythymidine can cause peripheral neuropathy
these inhibitors prevent cleavage of gag pol polyprotein, resulting in immature noninfectious viral particles
fusion entry inhibitors act on these receptors
These HIV seropositive patients never progress to AIDS
This protease inhibitor can cause hyperbilirubinemia with overt jaundice, increase in qt interval
Disfiguring major side effect of protease inhibitors
integrase inhibitor
abacavir associated with this HLA
Known as azt, this is used in preventing vertical transmission of HIV
These cells initiate infection by transporting HIV from mucosal surfaces to lymphoid tissue
this NRTI should not be taken with tetracycline or fluoroquinolone
AZT's highest toxicity
hyperpigmentation of the palms is a side effect of this drug
Protease inhibitors have this suffix
This type of HIV is found worldwide
The window period between infection and seroconversion is about ________ days
An important prognosticator of late stage disease
This enzyme cleaves viral proteins for viral assembly
this NRTI has dose dependent pancreatitis
Acronym: therapy for AIDS
Test: detect antibodies to HIV
The major receptor used by HIV to infect T cells
fusion inhibitor of gp41
This protein product is bound to CD4 and CXCR4 chemokine receptors
these 3 drugs should be taken on an empty stomach
zalcitabine should not be given with this NRTI
This area has the most substantial loss of cd4 T cells
entry inhibitor, ccr5
This NRTI competes with Stavudine and can cause myelosuppression
Lamivudine should be coadministered with this combo drug
This nnrti is a moderate inducer of cyp3a4
oral guanosine analog that can cross the bbb
During the early stage of HIV infection, this serum measurement is your most important predictor of progressive disease
The C in ABC stands for
Skin rash is a common result of these two nnrti
PI: most potent inhibitor of cyp3a4
hepatic steatosis and lipid metabolism disorder is an adverse reaction of this class of drugs
This PI is contraindicated with pts with hepatic failure and sulfa drug allergies
this class affects p450 and limits its effectiveness and creation
Test: viral load
PI for pregnant women
Long term non progressors have strong production of __________
This NRTI should be avoided if the patient is taking didanosine
This disease is the leading cause of infectious mortality in the world
definition: AIDS wasting
take this nnrti on an empty stomach, but watch out for CNS toxicity
mucosal ulcers and rash are part of the nonspecific symptoms of __________infection
This class of drugs does not need phosphorylation and does not compete with nucleoside triphosphate
lamivudine is a ______ analog
Heterozygosity of this compound imparts protection to AIDS
abacavir can cause this type of reaction
toxoplasma, mycobacterium, pneumocystis, and herpes cause this type of infection for aids patients
This gene makes the protein of the outer coating of the virus

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