Science Quiz / AIDS Day

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Can you name the AIDS Day?

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An important prognosticator of late stage disease
This type of HIV is found worldwide
This protease inhibitor can cause hyperbilirubinemia with overt jaundice, increase in qt interval
delavirdine, efavirenz, and PI's are ______ of cyp enzymes
These HIV seropositive patients never progress to AIDS
this class affects p450 and limits its effectiveness and creation
Skin rash is a common result of these two nnrti
AZT's highest toxicity
these 3 drugs should be taken on an empty stomach
This gene makes the protein of the outer coating of the virus
when given with lopinavir, this drug acts as a pharmacologic enhancer
oral guanosine analog that can cross the bbb
hepatic steatosis and lipid metabolism disorder is an adverse reaction of this class of drugs
This NRTI should be avoided if the patient is taking didanosine
Test: viral load
NRTI requires phosphorylation by _______ enzymes
This class of drugs does not need phosphorylation and does not compete with nucleoside triphosphate
This area has the most substantial loss of cd4 T cells
toxoplasma, mycobacterium, pneumocystis, and herpes cause this type of infection for aids patients
Coinfection with this virus promotes cytokines that resist AIDS
this NRTI has dose dependent pancreatitis
Test: detect antibodies to HIV
env cleaves this to form gp120+gp41
Acronym: therapy for AIDS
Test: detect HIV specific proteins
Lamivudine should be coadministered with this combo drug
abacavir can cause this type of reaction
This fluorinated analog of lamivudine can be taken once daily
it is important to maintain hydration on an empty stomach with this protease inhibitor
These cells initiate infection by transporting HIV from mucosal surfaces to lymphoid tissue
hyperpigmentation of the palms is a side effect of this drug
Activation of this immune cell initiates viral replication
entry inhibitor, ccr5
take this nnrti on an empty stomach, but watch out for CNS toxicity
The first T cells to die are those that are specific for fighting _____infection
integrase inhibitor
Heterozygosity of this compound imparts protection to AIDS
This NRTI competes with Stavudine and can cause myelosuppression
mucosal ulcers and rash are part of the nonspecific symptoms of __________infection
These patients have some degree of detectable viremia, but develop hiv about a decade later than normal
PI: most potent inhibitor of cyp3a4
lamivudine is a ______ analog
abacavir associated with this HLA
During the early stage of HIV infection, this serum measurement is your most important predictor of progressive disease
The C in ABC stands for
Disfiguring major side effect of protease inhibitors
Known as azt, this is used in preventing vertical transmission of HIV
these inhibitors prevent cleavage of gag pol polyprotein, resulting in immature noninfectious viral particles
This PI is contraindicated with pts with hepatic failure and sulfa drug allergies
PI for pregnant women
zalcitabine should not be given with this NRTI
adenosine analog with enteric coating, phenylalanine chewables, take on empty stomach
Long term non progressors have strong production of __________
Protease inhibitors have this suffix
This nnrti is a moderate inducer of cyp3a4
HIV can lead to a false negative when testing for this disease
NRTI: This analog of deoxythymidine can cause peripheral neuropathy
This gene encodes the reverse transcriptase, integrase, and protease
fusion inhibitor of gp41
definition: AIDS wasting
The major receptor used by HIV to infect T cells
This NRTI is used to treat hep B and should be administered with TMP SMZ
This protein product is bound to CD4 and CXCR4 chemokine receptors
The window period between infection and seroconversion is about ________ days
fusion entry inhibitors act on these receptors
This enzyme cleaves viral proteins for viral assembly
emtricitabine's oral solution contains this and is thus contraindicated in pregnant women and children
this NRTI should not be taken with tetracycline or fluoroquinolone
This disease is the leading cause of infectious mortality in the world

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