Science Quiz

Random Science or Biology Quiz

Biology Exam 3-5 Quiz Stats

 Plays Quiz not verified by Sporcle

Also try: Blurry Mammals
Challenge
Share
Tweet
Embed
Score 0/41 Timer 20:00
0 Plays Today
Hint Answer % Correct
Chemical signals that act on cells are calle d__________. They can be short or ____ distanceextracellular messages, long
66.7%
A___ are signaling molecules produced by a cell and act on that cell becuase the producing cell has receptors on its surface for signaling moleculeautocrines
66.7%
autocrines function at ___ distance and have a ____ life. They also act on like cells in vicinity with receptor for the_____short, short, signal
66.7%
Endocrine messages have ____ half lives and travel via the ____ to distant cellslong, blood
66.7%
The signaling message is the ____ ligand
66.7%
Binding of a __to its receptor, its receptor creates a conformational _in the receptor that exends to the cytoplamsic_ of the receptor allowing the cytoplamsic _ to interact ligand, change, domain, tail
66.7%
G-proteins bind GDP or ____ and are integral membrane proteinsGTP
66.7%
Binding site for GDP or GTP is on ___ chainalpha
66.7%
Cell signaling is by cell-cell _ and _ chemical signalscontact, soluble
33.3%
_____ messages act over a ____ distance and ____ half-lfe. They act on cells tthat are ___ than the cell that produced the signalParacrine, short, short, different
33.3%
One route is cytoplamsic domain of receprot activates an ____ assocaited with cytoplasmic tail, enzyme is a ____ and genereates a ___. enzyme, effector, second message
33.3%
Second route is cytoplasmic domain acts as a ____ for other proteins to bind to itdocking
33.3%
Both routes induce _____ reactions in cellsimilar
33.3%
Once the first intracellaur action occurs, there is a ____ of reactions cascade
33.3%
At the intiaiton of each step, the conformation of the protein that will enter the ______ is altered by a ____ or phosphatasecascade, kinase
33.3%
Kinases and phosphatases are ___ in cyto, exist as integral membrane and add or remove ____ on different proteins or single _______ residuessoluble, phosphates, amino acid
33.3%
At the end of a signaling pathway there is a _______target protein
33.3%
To sotp a cascade, ______ enzymes can degarde the intial _____ or in its soluble form before it binds to the _____extracellular, ligand, receptor
33.3%
Target proteins act to change - gene expression, __acitivties, __, cell _, ion __, DNA synthesis, cell deathenzyme, cytoskeleton, motility, permeability
33.3%
Signal receptors - G-protein coupled receptors, receptor protein-__kinases, ___-gated channels, ____hormone receptorstyrosine, ligand, steroid
33.3%
G-prtoeins are made of ____ subunits, an alpha, ____, gamma3, beta
33.3%
Hint Answer % Correct
G-protein coupled receptors have _ membrane spannng hydrophobic ___ helices that bind G-proteins. also known as ____7, alpha, 7TM
33.3%
The amino terminus of the receptor is _____extracellular
33.3%
The carboxyl terminus is ______intracellular
33.3%
Three outside loops of ______ join the transmembrane domains and these loops form the _____ for bidning the ligandpolypeptide, receptor
33.3%
Three inside loops of ______ also join the _______ domainspolypeptide, transmembrane
33.3%
These inside loops form the -____ site for prtoeins for signal _____ and particularly the ____ intracellualr loop binds g-proteinsbinding, transduction, third
33.3%
The _____terminus tail binds other proteins that form a scaffold to tlink the recepor to ____ proteins COOH, signaling
33.3%
This forms a receptor/G-protein complex and a change in conformation of the ___ subunit of the g-protein, when this occurs the bound ___ is releasedalpha, GDP
33.3%
Second messengars are usually ____ and will activate or _____ specific proteinssmall, inactivate
0%
The receptor-ligand complex can be ____ and degraded by _____ enzymes and someitmes the ____ is recycled to plasma memrbaneinternalized, lysosomal, receptor
0%
G-proteins are bound to ___ membrane side by lipids that are bound to the -__ and ___ chainsinner, alpha, gamma
0%
GPCR found everywwhere and tons of things can bind to them such as steriods, ____ and ____proteins, photons
0%
Binding of a ligand to GPCR causes a _ change in transmembrane ___ helices which causes a change in the third____ loop making it high ____ for the g-proteinconformational, alpha, intracellular, affinity
0%
With GDP bound, GPCR is ___, with ___ bound, GPCR is _____inactive, GTP, active
0%
One acitvated GPCR can activate a number of ____ amplyifying the responseg-proteins
0%
GPCR conf changes, the __ chain of the G-protein binds to the _loop of the receptor. Binding of the __ chain changes the _chain and the _ is replaced with GTPalpha, third, alpha, third, GDP
0%
The binding reduces the affinity f the alpha chain to the ___ and ___ chains of the g-protein and the alpha chain detachesbeta, gamma
0%
The free ____ chain with its bound GTP then activates an _____protein like adenylyl cyclse which breaks down ATP to ____ (second messenger)alpha, effector, cAMP
0%
In time, the ___ on the alpha chain is hydrolyzed to GDP, because it has _____GTP, GTPase
0%
0%

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Join for Free
OR
Log In

You Might Also Like...

Show Comments

Extras

Created Apr 4, 2012ReportNominate
Tags:Biology Quiz, 3-5, exam

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.

Report this User

Report this user for behavior that violates our Community Guidelines.

Details: