Science Quiz / Biology Exam 3-5

Random Science or Biology Quiz

Can you name the Biology Exam 3-5?

Quiz not verified by Sporcle

Forced Order
Also try: Leaping Animals
Challenge
Share
Tweet
Embed
Score 0/41 Timer 20:00
HintAnswer
Cell signaling is by cell-cell _ and _ chemical signals
Chemical signals that act on cells are calle d__________. They can be short or ____ distance
A___ are signaling molecules produced by a cell and act on that cell becuase the producing cell has receptors on its surface for signaling molecule
autocrines function at ___ distance and have a ____ life. They also act on like cells in vicinity with receptor for the_____
_____ messages act over a ____ distance and ____ half-lfe. They act on cells tthat are ___ than the cell that produced the signal
Endocrine messages have ____ half lives and travel via the ____ to distant cells
The signaling message is the ____
Binding of a __to its receptor, its receptor creates a conformational _in the receptor that exends to the cytoplamsic_ of the receptor allowing the cytoplamsic _ to interact
One route is cytoplamsic domain of receprot activates an ____ assocaited with cytoplasmic tail, enzyme is a ____ and genereates a ___.
Second messengars are usually ____ and will activate or _____ specific proteins
Second route is cytoplasmic domain acts as a ____ for other proteins to bind to it
Both routes induce _____ reactions in cell
Once the first intracellaur action occurs, there is a ____ of reactions
At the intiaiton of each step, the conformation of the protein that will enter the ______ is altered by a ____ or phosphatase
Kinases and phosphatases are ___ in cyto, exist as integral membrane and add or remove ____ on different proteins or single _______ residues
At the end of a signaling pathway there is a _______
To sotp a cascade, ______ enzymes can degarde the intial _____ or in its soluble form before it binds to the _____
The receptor-ligand complex can be ____ and degraded by _____ enzymes and someitmes the ____ is recycled to plasma memrbane
Target proteins act to change - gene expression, __acitivties, __, cell _, ion __, DNA synthesis, cell death
Signal receptors - G-protein coupled receptors, receptor protein-__kinases, ___-gated channels, ____hormone receptors
G-proteins bind GDP or ____ and are integral membrane proteins
HintAnswer
G-prtoeins are made of ____ subunits, an alpha, ____, gamma
G-proteins are bound to ___ membrane side by lipids that are bound to the -__ and ___ chains
Binding site for GDP or GTP is on ___ chain
G-protein coupled receptors have _ membrane spannng hydrophobic ___ helices that bind G-proteins. also known as ____
GPCR found everywwhere and tons of things can bind to them such as steriods, ____ and ____
The amino terminus of the receptor is _____
The carboxyl terminus is ______
Three outside loops of ______ join the transmembrane domains and these loops form the _____ for bidning the ligand
Three inside loops of ______ also join the _______ domains
These inside loops form the -____ site for prtoeins for signal _____ and particularly the ____ intracellualr loop binds g-proteins
The _____terminus tail binds other proteins that form a scaffold to tlink the recepor to ____ proteins
Binding of a ligand to GPCR causes a _ change in transmembrane ___ helices which causes a change in the third____ loop making it high ____ for the g-protein
This forms a receptor/G-protein complex and a change in conformation of the ___ subunit of the g-protein, when this occurs the bound ___ is released
With GDP bound, GPCR is ___, with ___ bound, GPCR is _____
One acitvated GPCR can activate a number of ____ amplyifying the response
GPCR conf changes, the __ chain of the G-protein binds to the _loop of the receptor. Binding of the __ chain changes the _chain and the _ is replaced with GTP
The binding reduces the affinity f the alpha chain to the ___ and ___ chains of the g-protein and the alpha chain detaches
The free ____ chain with its bound GTP then activates an _____protein like adenylyl cyclse which breaks down ATP to ____ (second messenger)
In time, the ___ on the alpha chain is hydrolyzed to GDP, because it has _____
 

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
OR
Log In

You Might Also Like...

Show Comments

Extras

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.