| Hint | Answer |
|---|
| Lysosomes contain a large variety of _____ enzymes that can digest | |
| To get to destination, vesicles move along ______ to destinations | |
| Also, tetherings on the ____vesicle bind to specific target vesicles or membranes. It is that a small G-protein, called ____, anchors the vesivle via a fibrous tethering protein at | |
| There are many different Rab proteins and they may provide some of the specificity for ____to a certain target | |
| . Rabs also recruit specific _______ tethering proteins to different membranes and regulate motor proteins that move vesicles along _____. | |
| Docking of vesicles occurs when the membranes of the two vesicles come into close contact by interaction of the _____ of integral membrane proteins | |
| These integral membrane proteins are called _____and consist of a family of about ___different _____. Although different, they all share a motif of _____ amino acids (the SNARE mot | |
| SNARES can be divided into two functional categories, __-SNARES and ___-SNARES. ___-SNAREs are on cargo vesicles and ___-SNARES are on _____compartments. | |
| Fusion of vesicles w/ target membranes occurs when t-SNARES and v-SNARES combine, pull their respective _____apart, allow the membranes to fuse. Also r | |
| It is the combination of ____, tethering proteins and _____ that provide the specificity for a vesicle to bind and fuse with the target membrane. | |
| Exocytosis occurs mostly ______ and is when a vesicle takes molecules from the inside of cells and releases them to the ______ environment. | |
| Exocytosis includes _____ proteins. The exocytic vesivle binds to the ____ membrane and small _____ pore is formed and the membranes fuse | |
| Lysosomes contain ___ digestive enzymes and have an acidcity of ____ because of proton pumps | |
| Lyosomes are involved in ____ which rids the cells of dead or damaged organelles, lyosomes fuse and degrade the organelle | |
| Autophagy - vesicle has double membrane from ___ | |
| Endocytosis occurs to engulf ______ receptors and ligands bound to them and extracellular ____ | |
| _____ is the engulfment of of particles greater than ____ microns | |
| _______ endocytosis is the uptake of extracellualr fluid, also known as pinocytosis | |
| ______endocytosis brings extracellular macromolecues into the cell when bound to cell surface receptors | |
| Receptor-mediated endocytosis is associated with ______pits | |
| Receptor =-meidated endo occurs to supply cell with _______, growth factors made by other cells and delivered to the target cell | |
| Specfic receptors are located in _______ to which various ligands can be interorized | |
| On the exterior of plasma mebrane you can see pits and on _____ side you can see accumulation of ____ molecules | |
| When the receptors bind to their ligands, the pil will forma a ____- and enter into the ctyoplasmm with its cargo | |
| The _____ on the outside of the vesicle will disassocaite | |
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