If humans are primary host, no morbidity. Worm just stays in gut. Intermediate host causes morbidity as organism in tissues
Live in subcutaneous tissue and lymphatic tissue. Adults discharge tiny babies which can be ingested by insects. Can cause Elephantiasis and River Blindness.
Ribavirin used, can be caused by alcohol
Hemaglutinnin, Neuraminidase, ...
Tetracycline often applied topically to cure
Death after Chloramphenicol
Can be oral or vaginal. Often treated with oral miconazole.
Increases risk of ATS
Egg dropped in faeces and mature in soil. they are ingested and hatch in intestine. they penetrate the gut wall and migrate to liver then heart then lung. they grow and are then coughed up and swallowed.10-30cm adult can escape from any orifice though larval migration causes most morbidity.