Science Quiz / Diseases in Infection and Immunity

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Can you name the Diseases in Infection and Immunity?

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Score 0/42 Timer 15:00
AreaDiseaseClue
Skin DiseaseTetracycline often applied topically to cure
InflammationTh2 (IL-4,5 & 13) and Eosinophil driven. Hyperresponsiveness
ArthopodsMite burrows into epidermis. Papular eruption.
FungusMore common where earth is being moved. In lungs.
Parasite (Helminth)Live in subcutaneous tissue and lymphatic tissue. Adults discharge tiny babies which can be ingested by insects. Can cause Elephantiasis and River Blindness.
InfectionIsoniazid/Ethambutol/Pyrazinamide/Rifampicin prescribed
Side EffectCan be caused by Clindamycin. Killing all susceptible bacteria in gut using a broad spectrum antibiotic can cause...
Side EffectDeath after Chloramphenicol
Virus/InflammationRibavirin used, can be caused by alcohol
ArthopodsItching in Pubic Area
Immune DeficiencyRecurrent bacterial infections, no pus, Leukocytes don't adhere to endothelium
BacteriaSusceptible to few drugs, often causes septicaemia. Susceptible to Ceftazidime, Cefoperazone, Cefepime, Cefpirome, Imipenem, Polymixins, Ciprofloxacin
BacteriaOften cause gut infection after oral broad spectrum antibiotic
Risk Factor - BacteriaCo-morbidity with ATS
Mendelian DisorderLDLR doesn't recognise ApoA or ApoE
Parasite (Helminth)Egg dropped in faeces and mature in soil. they are ingested and hatch in intestine. they penetrate the gut wall and migrate to liver then heart then lung. they grow and are then coughed up and swallowed.10-30cm adult can escape from any orifice though larval migration causes most morbidity.
Parasite (Protozoa)Multiplies in blood and CSF disturbing circadian rythms. avoids immune system by using cyclical antigen coats.
VirusCauses SARS
VirusHemaglutinnin, Neuraminidase, ...
Systemic InflammationRF present but not Rheumatoid Arthritis. Often features in 'House'
Parasite (Protozoa)Short stage in blood then muscle (esp. heart).
AreaDiseaseClue
Immune DeficiencyNeutrophilia, no pus, defective fucose metabolism (affects selectins), decreased rolling
Risk FactorIncreases risk of ATS
Parasite (Protozoa)They multiply in Liver then RBCs. Can cause severe anaemia, haemolysis, pulmonary oedema, metabolic acidosis and hypoglycaemia. Most serious in P. falciparum
Infection/InflammationCefotaxime/Ceftriaxone often prescribed. Caused by N. meningitidis, H. influenzae, S. pneumoniae, L. monocytogenes, possible C. albicans...
BacteriaOften susceptible to vancomycin and linezolid but resistant to Methicillin
ArthopodsScalp itching
FungusCaused by Yeast
Side EffectTetracyclin forms ROS causing damage
InflammationHomocysteine implicated
FungusCan be oral or vaginal. Often treated with oral miconazole.
Parasite (Helminth)If humans are primary host, no morbidity. Worm just stays in gut. Intermediate host causes morbidity as organism in tissues
VirusT cells increase but there are less T cells
FungusCaused by trichophyton (mould) often
Mendelian disorderABCA1 doesn't work so ApoA1 can't pick up cholesterol
Side EffectPenicillin can cause this in about 5% of people
VirusMost common cold causer
InflammationNeutrophil driven, often causes cyanosis, hypoxia and right heart failure. Mucous is a problem!
Parasite (Helminth)S. mansoni, S. haematobium, S. japonicus. Use water snail as intermediate host (can also have secondary host)
InflammationChronic Inflammation, Synovium (Hyaluronan, PGE2), MMPs (TIMP & Serpin inactivation), TNFa, IL-1b, Pannus formation
Side EffectAminoglycoside SE
BacteriaSusceptible to Linezolid but not vancomycin

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