Science Quiz / Oncology Drugs

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QUIZ: Can you name the common Oncology Drugs from Lectures?

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HintDrug/ClassClass
Used in colorectal cancerMonoclonal Antibody
Used in early/localised breast cancerMonoclonal Antibody
Topoisomerase I Inhibitor
(---) vaccine to prevent cancerCancer Vaccine
No attached drug or toxinMonoclonal Antibody
Taxane, associated with myalgia and alopeciaAntimitotic Agent
Vinca alkaloid, causes more neurotoxicityAntimitotic Agent
Reversibly inhibits EGFR, used in lung cancerTyrosine Kinase Inhibitor
Non-steroidal, starts with 'F'Antiandrogen
Binds to VEGFRAngiogenesis Inhibitor
5-FUAntimetabolite
Steroidal, starts with 'C'Antiandrogen
Comes in a pegylated lipsomal formAnthracycline
Non-steroidal, starts with 'B'Antiandrogen
SERM, more commonSERM
Inhibits tubulin polymerisationAntimitotic Agent
GnRH
6-MPAntimetabolite
Non-steroidal, starts with 'L'Aromatase Inhibitor
Nitrogen Mustard, causes haemorrhagic cystitisAlkylating Agent
Promote RBC, WBC, platelet production
Non-steroidal, starts with 'N'Antiandrogen
Platinum compound, causes nephrotoxicityAlkylating Agent
Vinca alkaloid, causes more myelosuppressionAntimitotic Agent
Platinum compound, causes 'less nausea'Alkylating Agent
HintDrug/ClassClass
Attached drug or toxin or radioactive materialMonoclonal Antibody
Inhibits microtubule disassemblyAntimitotic Agent
Blocks ribonucleoside reductaseOther Agent
Non-steroidal, starts with 'A'Aromatase Inhibitor
Folic acid antagonist, most commonAntimetabolite
Antibiotic + ChemotherapeuticAntibiotic
SteroidalAromatase Inhibitor
Binds to VEGFAngiogenesis Inhibitor
Taxane, associated with fluid retention and skin reactionsAntimitotic Agent
(---) vaccine to stimulate an immune responseCancer Vaccine
GnRH antagonist
Nitrosourea, causes fushign and oesophagitisAlkylating Agent
Shouldn't be used with Tamoxifen (SSRI)SSRI
Purine antagonist, metabolised by xanthine oxidaseAntimetabolite
Bind to and inhibit the enzyme aromatase
Binds competitively with oestrogen receptorsAntioestrogen
Pyrimidine antagonist, converted to FdUMP, causes alopeciaAntimetabolite
Three types (alpha, beta, gamma)Cytokine
SERM, less commonSERM
Immune-response-modifying agent, used for BCCsNucleoside Analogue
Blocks the activation of tyrosine kinase by EGT and TGF-a, used in lunc cancerMonoclonal Antibody
Podophyllotoxin Derivativeaka Topoisomerase II Inhibitor
WBC chemical signalCytokine
Competes with binding of ATP to the EGFR domain, used in lung cancerTyrosine Kinase Inhibitor
This class can lead to 'emasculation'/'feminisation' (no hyphen)

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