Science Quiz / Oncology Drugs

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Can you name the common Oncology Drugs from Lectures?

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HintDrug/ClassClass
Binds competitively with oestrogen receptorsAntioestrogen
Used in colorectal cancerMonoclonal Antibody
Shouldn't be used with Tamoxifen (SSRI)SSRI
Vinca alkaloid, causes more myelosuppressionAntimitotic Agent
Pyrimidine antagonist, converted to FdUMP, causes alopeciaAntimetabolite
Nitrogen Mustard, causes haemorrhagic cystitisAlkylating Agent
Comes in a pegylated lipsomal formAnthracycline
Blocks the activation of tyrosine kinase by EGT and TGF-a, used in lunc cancerMonoclonal Antibody
6-MPAntimetabolite
Taxane, associated with fluid retention and skin reactionsAntimitotic Agent
No attached drug or toxinMonoclonal Antibody
Purine antagonist, metabolised by xanthine oxidaseAntimetabolite
Inhibits tubulin polymerisationAntimitotic Agent
Competes with binding of ATP to the EGFR domain, used in lung cancerTyrosine Kinase Inhibitor
GnRH antagonist
GnRH
Non-steroidal, starts with 'A'Aromatase Inhibitor
Binds to VEGFAngiogenesis Inhibitor
Reversibly inhibits EGFR, used in lung cancerTyrosine Kinase Inhibitor
Immune-response-modifying agent, used for BCCsNucleoside Analogue
Blocks ribonucleoside reductaseOther Agent
WBC chemical signalCytokine
(---) vaccine to stimulate an immune responseCancer Vaccine
Inhibits microtubule disassemblyAntimitotic Agent
SteroidalAromatase Inhibitor
HintDrug/ClassClass
5-FUAntimetabolite
Promote RBC, WBC, platelet production
Non-steroidal, starts with 'F'Antiandrogen
SERM, less commonSERM
Vinca alkaloid, causes more neurotoxicityAntimitotic Agent
SERM, more commonSERM
Topoisomerase I Inhibitor
Podophyllotoxin Derivativeaka Topoisomerase II Inhibitor
Binds to VEGFRAngiogenesis Inhibitor
Attached drug or toxin or radioactive materialMonoclonal Antibody
Bind to and inhibit the enzyme aromatase
Nitrosourea, causes fushign and oesophagitisAlkylating Agent
Antibiotic + ChemotherapeuticAntibiotic
(---) vaccine to prevent cancerCancer Vaccine
Three types (alpha, beta, gamma)Cytokine
This class can lead to 'emasculation'/'feminisation' (no hyphen)
Platinum compound, causes nephrotoxicityAlkylating Agent
Non-steroidal, starts with 'B'Antiandrogen
Taxane, associated with myalgia and alopeciaAntimitotic Agent
Non-steroidal, starts with 'N'Antiandrogen
Platinum compound, causes 'less nausea'Alkylating Agent
Steroidal, starts with 'C'Antiandrogen
Non-steroidal, starts with 'L'Aromatase Inhibitor
Used in early/localised breast cancerMonoclonal Antibody
Folic acid antagonist, most commonAntimetabolite

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Created May 31, 2011ReportFavoriteNominate
Tags:oncology

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