Hint | Answer |
Test name for Arsenic | |
T or F: saturation kinetics involves half-lives | |
four ways to dope (4 single acronyms) in right order | |
T or F: UDS preferably on non-prolif cells (because S-phase has strong BrdU staining) | |
this creates CPDs aka T=T | |
1952 Act to clean England's airs | |
T or F: neoantigens can alter proteins directly or indirectly | |
name of extrapolation linear straight to zero eg for carcinogens (1 word) | |
separation is usually done by ____ techniques | |
tributyltin causes ____ in shellfish | |
Xeroderma Pigmentosum XP is caused by defects in which enzymes | |
probit unit 3-7 would include what % of pop | |
plant toxin that could kill you in small amounts | |
attributes of target criteria (3) right order | |
useful of interchr rearrangements, has the word paint | |
positive y-intercept DR extrapolation name | |
Germany 2011 epidemiology example | |
synthetic frameshift inducer | |
recombination: Grabs a piece of DNA not sister chromatid and can lead to chromo aberrations | |
eg of hormesis given by TS (4 full name) | |
Repair pathways (4, use acronyms) | |
identification is usually done by (3) | |
study that takes a group of people, one factor and see outcomes, can be prospective or retro | |
3 components of health risk assessment: | |
First food and drug law (USA) to band elixirs and stuff and their poisonings | |
Distrubution occurs via two systems: | |
name of extrapolation used for interactans and goes to zero on x-axis (1 word) | |
99% of all males have T/E ratio of | |
three types of forensic toxicology (3) in right order | |
key word for epidemiology: study of ___ that modify health | |
outcomes of toxicodynamics (3, single words) | |
to hide presence of illegal drugs | |
recombination: During G2, use of 2 chromatids, using one as template, less error prone than counterpart | |
indirubins bind this at low conc | |
name 3 kinetic 'special' locations (3 acronyms for 1) | |
IOC banned this before 1976 olympics in mtl | |
tributyltin is a ____ (class of compound) | |
NER and two types of repair | |
group of people together that came down with something | |
| Hint | Answer |
act requiring data on food, drug and cometics additives | |
greater or equal to one million pounds/yr | |
T or F: coroners have judicial role while medical have to be doctors; they deal with live patients | |
Recombination repair consists of these 2: | |
extraction is the process of making a ____ sample | |
four assesment of toxicodynamics (4) in right order | |
ways to create SS break | |
direct repair via this one-time-use enz | |
T or F:single base substitution, indel, duplication, translocation / single base, insertion and deletion, duplication, and translocation are the four types of mutations | |
this is a mutation hotspot | |
Indirect detection of DNA damage (1 way) | |
endogenous frameshift inducer | |
St anthony's fire fungal name | |
surface water sampled using this technique | |
RW Pount member of IOC creates this group, dedicated to test for doping drugs | |
1947: act saying that a susbtance that was neither drug had to be shown to be safe and efficacious | |
T or F: increase of rare disease, increase in an unusual population and increase in common disease / rare disease, unusual pop and common disease are presentation of disease cluste | |
USA list of industrial chemicals (name) | |
average number of SNPs in haplotype | |
uncontrollable and not observable eg | |
two types of exposures (2 single) in lecture 5 MC | |
Assumptions underying DE relationship (3) | |
the primary substance, pure, not mix, that causes tox effect | |
PAHs causes which type of cancer | |
drug used in micronuclei assay to block further cell division | |
a single base change in DNA observed among individuals groups, or pop occuring in at least 1% of pop, neither detrimental nor beneficial | |
three grid system soil samplings (3) | |
uses agarose gel, and measuring length of stuff | |
why results don't match with study (3 factors, single words) | |
T or F: potency vs efficacity is pretty much horizontal shifts vs max y-value, repectively | |
study that gives probable causation, retrospective only, disease vs non-disease, trying to figure what crucial factor is | |
agent to create DNA-DNA crosslink | |
Identification of chr abnormalibity by molecular hybridization of a labelled DNA probe | |
three types of SNPs (3) right order | |
two contols for air pollution experiment (2) | |
T or F: acetylation is more active in caucasians than in asians | |
agent caues gain or less of chr during chromatin condensation | |
mech of shiga toxin (2) | |
Mammalinan cytogenetic assays (3, use acronyms) | |
| Hint | Answer |
T or F: industrial revolution = lots of development in tox field | |
T or F: LD50 must be extrapolated | |
measure of distribution | |
T or F: p is long arm | |
study that looks for a correlation, can't set causation, ODDS ratio | |
ways to create DNA-protein cross link | |
use of a substance by any route, for non-theapy reasons to enhance performance | |
Alter bio enviro 4 ways (4) right order | |
Pharmacodynamics two ways (mech) (2, many words) | |
acetylation of amine groups done by? | |
sequential SNPs, or alleles, on sinle chr, rare sep by recombination | |
less than 1% of pop, usually harmful genomic change ass with human disease of increase or risk | |
LD50/ED50 | |
this group created the IOC | |
people have common polymorphisms in these type of enzymes | |
three routes of exposure (3 single words) order we learned + 4th is injection | |
any substance foreign to a bio system | |
two types of reaction types (2) | |
codeine is broken down by which cyp | |
measure of elim | |
4 types of mixture effects (4 single words) | |
movement through cells | |
cell responses to DNA damage (2, single words) | |
agent which induces increase freq of mutations | |
way to create DS break | |
name the two combination sep/ID procedures we learned (2) right order | |
pesticide list, 2000 active ingredients, on this list | |
small particles withing tiny water droplets, oth | |
list including substances used for manufacturing purposes or manufacture in or imported into Canada @ greater or equal to 100kg/year | |
Canada's workplace safety | |
LD1/ED99 | |
HPLC, mass spec, immunodetection involved in detecting these | |
T or F: genital area less vulnerable than other areas | |
health risk perception two factors (2, single words) | |
Canada's FDA | |
a big confounding factor | |
sampling schemes (4) in the order in class | |
Direct detection of DNA damage (3, two single words, one many) | |
movement between cells | |
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