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Mammalinan cytogenetic assays (3, use acronyms)
PAHs causes which type of cancer
ways to create DNA-protein cross link
eg of hormesis given by TS (4 full name)
Distrubution occurs via two systems:
Canada's workplace safety
endogenous frameshift inducer
tributyltin causes ____ in shellfish
probit unit 3-7 would include what % of pop
two types of exposures (2 single) in lecture 5 MC
measure of distribution
uncontrollable and not observable eg
1947: act saying that a susbtance that was neither drug had to be shown to be safe and efficacious
study that looks for a correlation, can't set causation, ODDS ratio
attributes of target criteria (3) right order
T or F: UDS preferably on non-prolif cells (because S-phase has strong BrdU staining)
name 3 kinetic 'special' locations (3 acronyms for 1)
drug used in micronuclei assay to block further cell division
agent to create DNA-DNA crosslink
mech of shiga toxin (2)
study that gives probable causation, retrospective only, disease vs non-disease, trying to figure what crucial factor is
cell responses to DNA damage (2, single words)
this creates CPDs aka T=T
name of extrapolation linear straight to zero eg for carcinogens (1 word)
First food and drug law (USA) to band elixirs and stuff and their poisonings
Assumptions underying DE relationship (3)
outcomes of toxicodynamics (3, single words)
two contols for air pollution experiment (2)
Xeroderma Pigmentosum XP is caused by defects in which enzymes
three types of SNPs (3) right order
extraction is the process of making a ____ sample
3 components of health risk assessment:
key word for epidemiology: study of ___ that modify health
tributyltin is a ____ (class of compound)
movement between cells
T or F: p is long arm
to hide presence of illegal drugs
use of a substance by any route, for non-theapy reasons to enhance performance
Repair pathways (4, use acronyms)
4 types of mixture effects (4 single words)
separation is usually done by ____ techniques
four assesment of toxicodynamics (4) in right order
Direct detection of DNA damage (3, two single words, one many)
T or F: genital area less vulnerable than other areas
Recombination repair consists of these 2:
Alter bio enviro 4 ways (4) right order
agent caues gain or less of chr during chromatin condensation
recombination: Grabs a piece of DNA not sister chromatid and can lead to chromo aberrations
Indirect detection of DNA damage (1 way)
T or F: acetylation is more active in caucasians than in asians
four ways to dope (4 single acronyms) in right order
three grid system soil samplings (3)
99% of all males have T/E ratio of
T or F: increase of rare disease, increase in an unusual population and increase in common disease / rare disease, unusual pop and common disease are presentation of disease cluste
T or F: saturation kinetics involves half-lives
list including substances used for manufacturing purposes or manufacture in or imported into Canada @ greater or equal to 100kg/year
T or F: potency vs efficacity is pretty much horizontal shifts vs max y-value, repectively
Canada's FDA
RW Pount member of IOC creates this group, dedicated to test for doping drugs
group of people together that came down with something
movement through cells
synthetic frameshift inducer
the primary substance, pure, not mix, that causes tox effect
pesticide list, 2000 active ingredients, on this list
T or F: coroners have judicial role while medical have to be doctors; they deal with live patients
T or F:single base substitution, indel, duplication, translocation / single base, insertion and deletion, duplication, and translocation are the four types of mutations
Test name for Arsenic
useful of interchr rearrangements, has the word paint
uses agarose gel, and measuring length of stuff
St anthony's fire fungal name
name the two combination sep/ID procedures we learned (2) right order
surface water sampled using this technique
greater or equal to one million pounds/yr
way to create DS break
T or F: LD50 must be extrapolated
less than 1% of pop, usually harmful genomic change ass with human disease of increase or risk
people have common polymorphisms in these type of enzymes
any substance foreign to a bio system
T or F: neoantigens can alter proteins directly or indirectly
this is a mutation hotspot
direct repair via this one-time-use enz
name of extrapolation used for interactans and goes to zero on x-axis (1 word)
why results don't match with study (3 factors, single words)
sampling schemes (4) in the order in class
three routes of exposure (3 single words) order we learned + 4th is injection
measure of elim
ways to create SS break
Pharmacodynamics two ways (mech) (2, many words)
act requiring data on food, drug and cometics additives
acetylation of amine groups done by?
sequential SNPs, or alleles, on sinle chr, rare sep by recombination
agent which induces increase freq of mutations
identification is usually done by (3)
HPLC, mass spec, immunodetection involved in detecting these
1952 Act to clean England's airs
indirubins bind this at low conc
Germany 2011 epidemiology example
IOC banned this before 1976 olympics in mtl
three types of forensic toxicology (3) in right order
study that takes a group of people, one factor and see outcomes, can be prospective or retro
NER and two types of repair
recombination: During G2, use of 2 chromatids, using one as template, less error prone than counterpart
Identification of chr abnormalibity by molecular hybridization of a labelled DNA probe
a single base change in DNA observed among individuals groups, or pop occuring in at least 1% of pop, neither detrimental nor beneficial
a big confounding factor
health risk perception two factors (2, single words)
two types of reaction types (2)
average number of SNPs in haplotype
codeine is broken down by which cyp
this group created the IOC
USA list of industrial chemicals (name)
plant toxin that could kill you in small amounts
small particles withing tiny water droplets, oth
T or F: industrial revolution = lots of development in tox field
positive y-intercept DR extrapolation name

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Created Feb 15, 2012ReportNominate

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