Science Quiz / Atherosclerosis

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Can you name the Atherosclerosis?

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QuestionAnswer
Protein imported into rough ER at the same time it is being translated
Clinical term for heart attack
____ binds to a protein made with an NLC signal and the ____ recognizes it and lets it in
LDL Mechanism: Macrophages ingest everything becoming _____ and eventually ____ occurs, dumping everything
Chest pain
In famililal hypercholesterolemia, there is a mutation in the _____
The ___ has 70% of the body's LDL receptors
Cholesterol goes to cells making enzymes in the ____ and inhibits them
Transport: from the outside to the ER
Differential diagnoses: inflammation of gall bladder
Clinical term for stroke
O-linked are ____, while N-linked are ____
Co Import Mechanism: ___ chops off the signal sequence
In the presence of ____ another lipid radical is formed (after o2)
LDL Mechanism: LDL floating around blood gets into the _______
controlled tissue death
In Po import, a _____ directs protein to nucleus
Co Import Mechanism: The _____ holds the ribosome, while _____ is used to boot out ____ to allow translation to start
Co Import Mechanism: The pore protein sits right above the _____, allowing the protein to be shoved into the lumen.
Eample of co-translation import protein
______ terminates radical chain reactions
Oligosaccharides is _____ that is linked to hydroxyl oxygen on ______ or _________
Most common surgery: removal of _____
A ____ sequence is 20 amino acids long, binding inside the pore membrane
The default destination for co import is ___
___ % of all cardiovascular deaths result from atherosclerosis
LDL Mechanism: ______ allow monocytes to get into the endothelium
the _________ and _________ reactions produce a ______ radical
A _____ can direct a co-translation import somewhere specified
Inherited elevated blood cholesterol
QuestionAnswer
Antioxidants include: (4), with the last one cells make by themselves
Transport: from the ER to outside
Cell sorting facility
The environment of an endosome is ____
In Po import, a _____ directs protein to mitochondria
Co Import Mechanism: On the mRNA there is a ____ that ____ recognizes causing ____ to stop
Example of post-translational import
For any tranfusion to work out, you need the same _____ type, ____ factor, and _____ complex
Disease of large and medium arteries, results in accumulates of smooth muscle cells and lipids within intima
Dietary ion-exchange resins bind to _____
Differential diagnoses: gall stones
_____ are cholesterol synthesis inhibitors
In the endosome, ligands fall of because the _____, changes the _____ of proteins
With clathrin surrounding the vesicle is it known as _____
Uncontrolled tissue death
Atherosclerosis pathogenesis: Fat accumulation in intima
Atherosclerosis pathogenesis: Blood rip endothelial cells due ot force exposing media
Bacteria in athero plaques are the same as those in ______ disease
Atherosclerosis does not occur in the _____
The Nucleus has a ___ envelopes which is continuous with the ____ and _____
Middle layer of arteries is______ and it contains ___________ cells
LDL Mechanism: Monocytes become _________ and secrete ______
strep throat bacteria, causes heart disease if untreated
LDLs are composed of a ____ membrane with an interior of _____ and _______
 
Familial hypercholesterolemia is due to a mutation in the _________
trouble breathing
Acid hydrolyases made in the ER are shipped to the _____ where enzymes recognize it and add a ________ group to it
Atherosclerosis pathogenesis: _____ form causing blockagein blood vessel
Hardening of arteries is _____ caused by ____ deposits in connective tissue
QuestionAnswer
Differential diagnoses: a tear in aorta
These act as handles or identifiers for lipoproteins
The ER environemt _______ form, _______ of proteins occur, ______ off things occurs, and _______ assembly occurs, and _______
The _____ receptor recognizes mannose-6-phosphate and a _____ vesicle is made
A hydroxyl radical and a lipid together react to get _____ and a ________radical
LDLs are marked by _____
Intima is composed of __________ and a ____ layer of _____ cells
Blood Types: The inheritance of _____ transferase for A antige, _____ transferase for B antigen
Liver turns chylomicrons into _________ which once taken up by cells are turned into _________
________ produces superoxide and peroxide continuously at low levels
The layer of artery containing nerves, connective tissue, and fat
Clathrin is made of __ heavy chains and __ light chains
LDLs are considered a _______ system
Not oxygenated
An ____ protein links _____ to receptors (endocytosis)
Protein manufactured in cytoplasm and then imported into rough ER
fainting
Blood type AB is known as universal _____ while type O is known as universal ________
excess sweating
In the presence of oxygen, lipid radicals turn into _______ radical and a _________ radical again
Oligosaccharides is ______ that is linked to amide nitrogen on _____
Chylomcrions are transported to ____, _______, and _______
Differential diagnoses: inflammation of pericardium
Triglycerides are a preferred energy source for ____ and ____
LDL Mechanism: LDL becomes _____, stimulating the ____ to recruit______
_____ enhances LDL uptake (drug)
Atherosclerosis pathogenesis: Depots of fats that are under transparent layer of cells in intima
HDLs are also secreted by the liver and marked by _____, and once taken by cells are turned into
LDLs are ____ and considered ___ cholesterol

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Created May 6, 2012ReportNominate

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