Science Quiz / Atherosclerosis

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Can you name the Atherosclerosis?

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In Po import, a _____ directs protein to mitochondria
Protein imported into rough ER at the same time it is being translated
Co Import Mechanism: On the mRNA there is a ____ that ____ recognizes causing ____ to stop
Cholesterol goes to cells making enzymes in the ____ and inhibits them
In the presence of oxygen, lipid radicals turn into _______ radical and a _________ radical again
LDL Mechanism: Macrophages ingest everything becoming _____ and eventually ____ occurs, dumping everything
LDL Mechanism: LDL becomes _____, stimulating the ____ to recruit______
In the endosome, ligands fall of because the _____, changes the _____ of proteins
Chest pain
With clathrin surrounding the vesicle is it known as _____
Clinical term for stroke
Atherosclerosis does not occur in the _____
Hardening of arteries is _____ caused by ____ deposits in connective tissue
Differential diagnoses: gall stones
In the presence of ____ another lipid radical is formed (after o2)
______ terminates radical chain reactions
Disease of large and medium arteries, results in accumulates of smooth muscle cells and lipids within intima
The environment of an endosome is ____
excess sweating
Blood Types: The inheritance of _____ transferase for A antige, _____ transferase for B antigen
A _____ can direct a co-translation import somewhere specified
Atherosclerosis pathogenesis: Depots of fats that are under transparent layer of cells in intima
A ____ sequence is 20 amino acids long, binding inside the pore membrane
Uncontrolled tissue death
LDLs are composed of a ____ membrane with an interior of _____ and _______
The Nucleus has a ___ envelopes which is continuous with the ____ and _____
LDLs are marked by _____
___ % of all cardiovascular deaths result from atherosclerosis
trouble breathing
Blood type AB is known as universal _____ while type O is known as universal ________
Middle layer of arteries is______ and it contains ___________ cells
LDL Mechanism: ______ allow monocytes to get into the endothelium
The layer of artery containing nerves, connective tissue, and fat
Co Import Mechanism: The pore protein sits right above the _____, allowing the protein to be shoved into the lumen.
O-linked are ____, while N-linked are ____
strep throat bacteria, causes heart disease if untreated
Differential diagnoses: a tear in aorta
Oligosaccharides is _____ that is linked to hydroxyl oxygen on ______ or _________
the _________ and _________ reactions produce a ______ radical
For any tranfusion to work out, you need the same _____ type, ____ factor, and _____ complex
HDLs are also secreted by the liver and marked by _____, and once taken by cells are turned into
Intima is composed of __________ and a ____ layer of _____ cells
Transport: from the outside to the ER
An ____ protein links _____ to receptors (endocytosis)
Example of post-translational import
Atherosclerosis pathogenesis: Fat accumulation in intima
Antioxidants include: (4), with the last one cells make by themselves
In Po import, a _____ directs protein to nucleus
Oligosaccharides is ______ that is linked to amide nitrogen on _____
LDLs are ____ and considered ___ cholesterol
The ___ has 70% of the body's LDL receptors
Transport: from the ER to outside
Eample of co-translation import protein
A hydroxyl radical and a lipid together react to get _____ and a ________radical
____ binds to a protein made with an NLC signal and the ____ recognizes it and lets it in
controlled tissue death
Differential diagnoses: inflammation of pericardium
_____ are cholesterol synthesis inhibitors
In famililal hypercholesterolemia, there is a mutation in the _____
Most common surgery: removal of _____
Co Import Mechanism: ___ chops off the signal sequence
Differential diagnoses: inflammation of gall bladder
The _____ receptor recognizes mannose-6-phosphate and a _____ vesicle is made
LDL Mechanism: Monocytes become _________ and secrete ______
Bacteria in athero plaques are the same as those in ______ disease
Clinical term for heart attack
Liver turns chylomicrons into _________ which once taken up by cells are turned into _________
Familial hypercholesterolemia is due to a mutation in the _________
Inherited elevated blood cholesterol
LDLs are considered a _______ system
Not oxygenated
________ produces superoxide and peroxide continuously at low levels
_____ enhances LDL uptake (drug)
Cell sorting facility
Atherosclerosis pathogenesis: _____ form causing blockagein blood vessel
These act as handles or identifiers for lipoproteins
The default destination for co import is ___
Atherosclerosis pathogenesis: Blood rip endothelial cells due ot force exposing media
Acid hydrolyases made in the ER are shipped to the _____ where enzymes recognize it and add a ________ group to it
The ER environemt _______ form, _______ of proteins occur, ______ off things occurs, and _______ assembly occurs, and _______
Triglycerides are a preferred energy source for ____ and ____
Co Import Mechanism: The _____ holds the ribosome, while _____ is used to boot out ____ to allow translation to start
Chylomcrions are transported to ____, _______, and _______
LDL Mechanism: LDL floating around blood gets into the _______
Dietary ion-exchange resins bind to _____
Protein manufactured in cytoplasm and then imported into rough ER
Clathrin is made of __ heavy chains and __ light chains

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