Science Quiz / DVT/PE treatments

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QUIZ: Can you name the treatments and patho questions relating to DVT/PE?

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QuestionAnswer
Which clotting factors require activation in the liver by vitamin K? (name in ascending numerical order)
Which clotting factor initiates the intrinsic pathway, after exposure to collagen?
What is the parent compound of direct thrombin inhibitors?
Which tissue protein allows factor VII to initiate the extrinsic pathway?
What environmental change initiates platelet adhesion in the collagen pathway?
What molecule cross-links platelets after they have been activated?
Name a coagulation inhibitor produced naturally by the human body.
Name the preferred DTI to use in a patient with HIT, ESRD, and cirrhosis.
Name a drug that mimics tissue plasminogen activator, used in the treatment of pulmonary embolism.
How soon from the start of therapy would you expect to see skin necrosis as a side effect of warfarin?
QuestionAnswer
How many times more potent is S-warfarin than R-warfarin?
What are venous thrombi mostly composed of? (2 things)
How many units of heparin would 4.5mg of protamine neutralize?
What arterial thrombi mostly composed of?
Name a synthetic factor Xa inhibitor used to prevent DVT.
Increased metabolism of ______ ______ would result in a decrease in warfarin dose in a patient who becomes hyperthyroid.
What is the half-life of Heparin?
Which factor of Virchow's triad would CHF contribute to?
Name a macrolide antibiotic that would NOT increase the effect of warfarin.
What CYP enzyme is primarily responsible for metabolizing S-warfarin?

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